The dopamine agonist pramipexole scavenges hydroxyl free radicals induced by striatal application of 6-hydroxydopamine in rats: an in vivo microdialysis study

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

The rat brain in stereotaxic coordinates

1983 • 28,962 citations

Brain dopamine and the syndromes of Parkinson and Huntington Clinical, morphological and neurochemical correlations

1973 • 2,615 citations

Verteilung Von Noradrenalin Und Dopamin (3-Hydroxytyramin) Im Gehirn Des Menschen Und Ihr Verhalten Bei Erkrankungen Des Extrapyramidalen Systems

1960 • 1,863 citations

Basal Lipid Peroxidation in Substantia Nigra Is Increased in Parkinson's Disease

1989 • 1,369 citations

Oxidative DNA Damage in the Parkinsonian Brain: An Apparent Selective Increase in 8‐Hydroxyguanine Levels in Substantia Nigra

1997 • 822 citations

Time course of nigrostriatal degeneration in parkinson's disease

1976 • 561 citations

A Generalised Increase in Protein Carbonyls in the Brain in Parkinson's but Not Incidental Lewy Body Disease

1997 • 549 citations

Oxidative mechanisms in nigral cell death in Parkinson's disease.

1998 • 517 citations

Pramipexole binding and activation of cloned and expressed dopamine D2, D3 and D4 receptors

1995 • 249 citations

Dopamine D2 receptor-mediated antioxidant and neuroprotective effects of ropinirole, a dopamine agonist

1999 • 205 citations

Pramipexole Reduces Reactive Oxygen Species Production In Vivo and In Vitro and Inhibits the Mitochondrial Permeability Transition Produced by the Parkinsonian Neurotoxin Methylpyridinium Ion

1998 • 188 citations

Pharmacology of pramipexole, a dopamine D3-preferring agonist useful in treating Parkinson's disease.

1998 • 156 citations

Bromocriptine protects mice against 6-hydroxydopamine and scavenges hydroxyl free radicals in vitro

1994 • 155 citations

Apomorphine is a highly potent free radical scavenger in rat brain mitochondrial fraction

1996 • 137 citations

Biochemical and pharmacological studies on pramipexole, a potent and selective dopamine D2 receptor agonist

1992 • 135 citations

Neuroprotective effects of the dopamine D 2 /D 3 agonist pramipexole against postischemic or methamphetamine-induced degeneration of nigrostriatal neurons

1996 • 131 citations

Antioxidant Properties of Bromocriptine, a Dopamine Agonist

1994 • 116 citations

Neuroprotection by pramipexole against dopamine- and levodopa-induced cytotoxicity

1999 • 105 citations

L-DOPA increases nigral production of hydroxyl radicals in vivo

1994 • 96 citations

Attenuation of levodopa-induced toxicity in mesencephalic cultures by pramipexole

1997 • 96 citations

Levodopa induces apoptosis in cultured neuronal cells—A possible accelerator of nigrostriatal degeneration in Parkinson's disease?

1997 • 89 citations

Pramipexole, a dopamine D2 autoreceptor agonist, decreases the extracellular concentration of dopamine in vivo

1991 • 77 citations

Effects of nicotine on hydroxyl free radical formation in vitro and on MPTP-induced neurotoxicity in vivo

1998 • 75 citations

Levodopa neurotoxicity

1998 • 74 citations

Neuroprotection by dopamine agonists.

1994 • 62 citations

Neuroprotective effects of the dopamine agonists pramipexole and bromocriptine in 3-acetylpyridine-treated rats

1997 • 60 citations

Pergolide scavenges both hydroxyl and nitric oxide free radicals in vitro and inhibits lipid peroxidation in different regions of the rat brain

1998 • 59 citations

Malonate‐Induced Generation of Reactive Oxygen Species in Rat Strium Depends on Dopamine Release but Not on NMDA Receptor Activation

1999 • 58 citations

Inhibitory Effects of Talipexole and Pramipexole on MPTP-Induced Dopamine Reduction in the Striatum of C57BL/6N Mice.

1997 • 52 citations

The salicylate hydroxylation assay to measure hydroxyl free radicals induced by local application of glutamate in vivo or induced by the Fenton reaction in vitro

2000 • 45 citations

Free radical scavenging properties of apomorphine enantiomers and dopamine: Possible implication in their mechanism of action in parkinsonism

1995 • 43 citations

Value of drug-licensing documents in studying the effect of postmenopausal hormone therapy on cardiovascular disease

2000 • 39 citations

Effects of α‐Phenyl‐tert‐Butylnitrone and Selegiline on Hydroxyl Free Radicals in Rat Striatum Produced by Local Application of Glutamate

1998 • 38 citations

High affinity binding for pramipexole, a dopamine D3 receptor ligand, in rat striatum

1996 • 34 citations

Striatal dopamine participates in glutamateinduced hydroxyl radical generation

1995 • 29 citations

Effects of pergolide treatment on in vivo hydroxyl free radical formation during infusion of 6-hydroxydopamine in rat striatum

1998 • 28 citations

Neurotransmitters and Disorders of the Basal Ganglia

1999 • 22 citations

Effect of piribedil, a D-2 dopaminergic agonist, on dopamine, amino acids, and free radicals in gerbil brain after cerebral ischemia

1995 • 20 citations

Talipexole or pramipexole combinations with chloro-APB (SKF 82958) in MPTP-induced hemiparkinsonian monkeys

1997 • 19 citations

Comparison of the novel drug Ensaculin with MK-801 on the reduction of hydroxyl radical production in rat striatum after local application of glutamate

2000 • 16 citations

Parkinson's disease research moves on briskly

1999 • 11 citations

Talipexole protects dopaminergic neurons from methamphetamine toxicity in C57BL/6N mouse

1998 • 10 citations