Meta-analysis in the assessment of treatment outcome

Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials

2005 • 7,244 citations

Effectiveness of Antipsychotic Drugs in Patients with Chronic Schizophrenia

2005 • 5,799 citations

A Comparison of Results of Meta-analyses of Randomized Control Trials and Recommendations of Clinical Experts

1992 • 1,451 citations

Atypical antipsychotics in the treatment of schizophrenia: systematic overview and meta-regression analysis

2000 • 1,079 citations

Systematic Review: Why sources of heterogeneity in meta-analysis should be investigated

1994 • 947 citations

A Randomized Trial of Aspirin and Sulfinpyrazone in Threatened Stroke

1978 • 933 citations

The Medical Review Article: State of the Science

1987 • 859 citations

Subgroup analysis in randomised controlled trials: importance, indications, and interpretation

2005 • 859 citations

Design and use of questionnaires: a review of best practice applicable to surveys of health service staff and patients

2001 • 787 citations

Why do we need some large, simple randomized trials?

1984 • 692 citations

Lithium in the Prevention of Suicidal Behavior and All-Cause Mortality in Patients With Mood Disorders: A Systematic Review of Randomized Trials

2005 • 601 citations

A Pooled Analysis of 2 Placebo-Controlled 18-Month Trials of Lamotrigine and Lithium Maintenance in Bipolar I Disorder

2004 • 582 citations

Subgroup analyses in randomised controlled trials: quantifying the risks of false-positives and false-negatives

2001 • 542 citations

Practical methodology of meta‐analyses (overviews) using updated individual patient data

1995 • 472 citations

Cochrane Collaboration Handbook

1996 • 405 citations

Content and quality of 2000 controlled trials in schizophrenia over 50 years

1998 • 369 citations

Schizophrenia and Complications of Pregnancy and Labor: An Individual Patient Data Meta-analysis

1999 • 310 citations

Systematic Reviews: Meta-analysis and its problems

1994 • 276 citations

Lower suicide risk with long‐term lithium treatment in major affective illness: a meta‐analysis

2001 • 264 citations

Meta‐analysis of continuous outcome data from individual patients

2001 • 263 citations

Pharmacogenetics of Tardive Dyskinesia Combined Analysis of 780 Patients Supports Association with Dopamine D3 Receptor Gene Ser9Gly Polymorphism

2002 • 241 citations

Combined analysis of 635 patients confirms an age-related association of the serotonin 2A receptor gene with tardive dyskinesia and specificity for the non-orofacial subtype

2005 • 115 citations

Clinical trials in psychiatry

1983 • 103 citations

Comparison of systematic and narrative reviews: the example of the atypical antipsychotics

2003 • 100 citations

Meta‐analysis of ordinal outcomes using individual patient data

2001 • 89 citations

Meta-analysis of brain weight in schizophrenia

2003 • 87 citations

Bipolar disorder: clinical uncertainty, evidence-based medicine and large-scale randomised trials

2001 • 51 citations