Optical measurement of synaptic glutamate spillover and reuptake by linker optimized glutamate-sensitive fluorescent reporters

A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications

2002 • 2,692 citations

Engineering and characterization of a superfolder green fluorescent protein

2005 • 2,229 citations

Engineering green fluorescent protein for improved brightness, longer wavelengths and fluorescence resonance energy transfer

1996 • 1,462 citations

Astrocyte-mediated control of cerebral blood flow

2005 • 1,092 citations

The Time Course of Glutamate in the Synaptic Cleft

1992 • 1,071 citations

Reducing the Environmental Sensitivity of Yellow Fluorescent Protein

2001 • 1,013 citations

Expanded dynamic range of fluorescent indicators for Ca ²⁺ by circularly permuted yellow fluorescent proteins

2004 • 1,009 citations

Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex

1994 • 988 citations

Quantitative Ultrastructural Analysis of Hippocampal Excitatory Synapses

1997 • 973 citations

Circular permutation and receptor insertion within green fluorescent proteins

1999 • 913 citations

NMDA spikes in basal dendrites of cortical pyramidal neurons

2000 • 701 citations

Inactivity Produces Increases in Neurotransmitter Release and Synapse Size

2001 • 620 citations

Heterogeneous Release Properties of Visualized Individual Hippocampal Synapses

1997 • 605 citations

Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering

2001 • 583 citations

Use-dependent increases in glutamate concentration activate presynaptic metabotropic glutamate receptors

1997 • 469 citations

Detection of glutamate release from neurons by genetically encoded surface-displayed FRET nanosensors

2005 • 383 citations

Construction of a fluorescent biosensor family

2002 • 324 citations

Discussion

1997 • 310 citations

Imaging Extracellular Waves of Glutamate during Calcium Signaling in Cultured Astrocytes

2000 • 296 citations

Building and breeding molecules to spy on cells and tumors

2004 • 294 citations

Cytosolic calcium oscillations in astrocytes may regulate exocytotic release of glutamate.

2001 • 283 citations

Submillisecond Precision of the Input-Output Transformation Function Mediated by Fast Sodium Dendritic Spikes in Basal Dendrites of CA1 Pyramidal Neurons

2003 • 267 citations

Cytosolic Calcium Oscillations in Astrocytes May Regulate Exocytotic Release of Glutamate

2001 • 264 citations

Induction of sharp wave–ripple complexes in vitro and reorganization of hippocampal networks

2005 • 261 citations

Cooperation between independent hippocampal synapses is controlled by glutamate uptake

2002 • 256 citations

Rates of ligand binding to periplasmic proteins involved in bacterial transport and chemotaxis.

1983 • 251 citations

Release of endogenous excitatory amino acids from turtle photoreceptors

1989 • 250 citations

In vivo brain imaging using a portable 39?gram two-photon fluorescence microendoscope

2005 • 249 citations

Construction and optimization of a family of genetically encoded metabolite sensors by semirational protein engineering

2005 • 239 citations

Multiple climbing fibers signal to molecular layer interneurons exclusively via glutamate spillover

2007 • 231 citations

Glutamate Spillover Mediates Excitatory Transmission in the Rat Olfactory Bulb

1999 • 226 citations

Glutamate and γ-aminobutyric acid mediate a heterosynaptic depression at mossy fiber synapses in the hippocampus

1999 • 182 citations

Extrasynaptic NR2B and NR2D subunits of NMDA receptors shape ‘superslow’ afterburst EPSC in rat hippocampus

2004 • 162 citations

Deriving the Glutamate Clearance Time Course from Transporter Currents in CA1 Hippocampal Astrocytes: Transmitter Uptake Gets Faster during Development

2005 • 162 citations

Synaptically Released Glutamate Does Not Overwhelm Transporters on Hippocampal Astrocytes During High-Frequency Stimulation

2000 • 154 citations

Glutamate Release Monitored with Astrocyte Transporter Currents during LTP

1998 • 149 citations

Optical glutamate sensor for spatiotemporal analysis of synaptic transmission

2007 • 83 citations

Enhancement of glutamate release uncovers spillover-mediated transmission by N-methyl-d-aspartate receptors in the rat hippocampus

1999 • 80 citations

Real Time in Vivo Measures of l‐Glutamate in the Rat Central Nervous System Using Ceramic‐Based Multisite Microelectrode Arrays

2003 • 62 citations

The `sniffer-patch' technique for detection of neurotransmitter release

1997 • 51 citations