Antigen presenting cell function is enhanced in healthy elderly

Lymphokine Production by Human T Cells in Disease States

1994 • 1,351 citations

Age Influence on the Immune System

1980 • 703 citations

Aging and Immune Function

1991 • 361 citations

Interaction between Protein-Derived Immunogenic Peptides and Ia

1986 • 180 citations

Accessory Cell Signals Involved in T‐Cell Activation

1990 • 160 citations

Age‐related changes in lymphokine production related to a decreased number of CD45RB^hi CD4⁺ T cells

1991 • 154 citations

Role of T cells and adherent cells in age-related decline in murine interleukin 2 production.

1982 • 153 citations

Macrophage prostaglandin production contributes to the age-associated decrease in T cell function which is reversed by the dietary antioxidant vitamin E

1997 • 152 citations

The aging immune system: Primary and secondary alterations of immune reactivity in the elderly

1997 • 142 citations

Influence of age on the production and regulation of interleukin-1 in mice.

1985 • 138 citations

Age-related effects in T cell activation and proliferation

1993 • 124 citations

Evidence of enhanced type 2 immune response and impaired upregulation of a type 1 response in frail elderly nursing home residents

1997 • 88 citations

IL-12 directly stimulates expression of IL-10 by CD5+ B cells and IL-6 by both CD5+ and CD5- B cells: possible involvement in age-associated cytokine dysregulation

1997 • 88 citations

Senescence and cytokines modulate the NK cell expression

1997 • 75 citations

Altered regulation of inducible nitric oxide synthase expression in macrophages from senescent mice

1996 • 70 citations

Age‐related increase of CD45RO⁺ lymphocytes in physically active adults

1993 • 65 citations

T cell activation in the elderly: Evidence for specific deficiencies in T cell/accessory cell interactions

1990 • 54 citations

Accessory Function and Properties of Monocytes from Healthy Elderly Humans for T Lymphocyte Responses to Mitogen and Antigen

1993 • 51 citations

Functional Competence of Dendritic Cells of Ageing C57BL/6 Mice

1986 • 47 citations

Impaired Antigen Presenting Function of Macrophages from Aged Mice

1985 • 32 citations

Mel14⁺CD4⁺ T cells from aged mice display functional and phenotypic characteristics of memory cells

1994 • 27 citations

Age-related changes in the expression of T cell activation antigens following phytohaemagglutinin stimulation.

1992 • 22 citations

Age-associated changes in lymphoid and antigen-presenting cell functions in mice immunized with Trypanosoma cruzi antigens

1996 • 17 citations

CD8 alphabeta+ TCR alphabeta(intermediate) lymphocytes expressing skewed TCRVbeta repertoire in the liver of aged athymic nu/nu mice.

1997 • 15 citations

Lepromin-induced suppressor cells in lepromatous leprosy

1987 • 14 citations

Immunosenescence Revisited

1997 • 6 citations