Epithelial Defensins Impair Adenoviral Infection: Implication for Adenovirus-Mediated Gene Therapy

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

1987 • 11,491 citations

The role of cationic antimicrobial peptides in innate host defences

2000 • 1,184 citations

Human β-Defensin-1 Is a Salt-Sensitive Antibiotic in Lung That Is Inactivated in Cystic Fibrosis

1997 • 1,069 citations

Cystic Fibrosis Airway Epithelia Fail to Kill Bacteria Because of Abnormal Airway Surface Fluid

1996 • 1,042 citations

Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis

1994 • 829 citations

Human beta-defensin-1: an antimicrobial peptide of urogenital tissues.

1998 • 733 citations

Improved silver staining procedure for fast staining in PhastSystem Development Unit. I. Staining of sodium dodecyl sulfate gels

1988 • 697 citations

Update on adenovirus and its vectors

2000 • 605 citations

Production of β-defensins by human airway epithelia

1998 • 574 citations

Widespread expression of beta‐defensin hBD‐1 in human secretory glands and epithelial cells

1996 • 571 citations

A Controlled Study of Adenoviral-Vector–Mediated Gene Transfer in the Nasal Epithelium of Patients with Cystic Fibrosis

1995 • 571 citations

hBD‐1: a novel β‐defensin from human plasma

1995 • 547 citations

Direct inactivation of viruses by human granulocyte defensins

1986 • 525 citations

Epithelial Antibiotics Induced at Sites of Inflammation

1995 • 417 citations

Inefficient gene transfer by adenovirus vector to cystic fibrosis airway epithelia of mice and humans

1994 • 373 citations

Enteric defensins: antibiotic peptide components of intestinal host defense.

1992 • 310 citations

Human Enteric Defensins

1996 • 301 citations

Inducible expression of an antibiotic peptide gene in lipopolysaccharide-challenged tracheal epithelial cells.

1996 • 277 citations

Human airway epithelia express a beta-defensin.

1997 • 264 citations

Broad-spectrum antimicrobial activity of human intestinal defensin 5

1997 • 228 citations

Adenovirus-mediated gene transfer for cystic fibrosis: quantitative evaluation of repeated in vivo vector administration to the lung.

1994 • 188 citations

Localization of human intestinal defensin 5 in Paneth cell granules

1997 • 188 citations

Direct inactivation of viruses by MCP-1 and MCP-2, natural peptide antibiotics from rabbit leukocytes

1985 • 180 citations

Aerosol Administration of a Recombinant Adenovirus Expressing CFTR to Cystic Fibrosis Patients: A Phase I Clinical Trial

1997 • 177 citations

Defensins in granules of phagocytic and non-phagocytic cells

1995 • 129 citations

Correction of cAMP-Stimulated Fluid Secretion in Cystic Fibrosis Airway Epithelia: Efficiency of Adenovirus-Mediated Gene Transfer In Vitro

1994 • 95 citations

Production of active bovine tracheal antimicrobial peptide in milk of transgenic mice

1996 • 63 citations

Virus-Mediated Gene Transfer for Cutaneous Gene Therapy

2000 • 43 citations

Regenerating Cells in Human Airway Surface Epithelium Represent Preferential Targets for Recombinant Adenovirus

1995 • 42 citations

Expression of Human ß-defensin 1 mRNA in Human Nasal Mucosa

2000 • 17 citations

Potential Applications of Gene Therapy in the Patient with Cancer

2000 • 15 citations