Purification and mutant analysis of Citrobacter freundii AmpR, the regulator for chromosomal AmpC β‐lactamase

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Experiments in molecular genetics

1972 • 28,260 citations

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes.

1987 • 5,066 citations

Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid

1978 • 4,472 citations

Construction and characterization of new cloning vehicle. II. A multipurpose cloning system

1977 • 3,829 citations

A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments

1982 • 3,041 citations

STUDIES ON LYSOGENESIS I

1951 • 3,007 citations

Analysis of gene control signals by DNA fusion and cloning in Escherichia coli

1980 • 2,499 citations

PROTEIN-DNA RECOGNITION

1984 • 1,649 citations

Construction and characterization of new cloning vehicles I. Ampicillin-resistant derivatives of the plasmid pMB9

1977 • 1,055 citations

Molecular cloning of the plasmid RP4 primase region in a multi-host-range tacP expression vector

1986 • 1,053 citations

The tac promoter: a functional hybrid derived from the trp and lac promoters.

1983 • 1,001 citations

Transcriptional Regulator of Oxidative Stress-Inducible Genes: Direct Activation by Oxidation

1990 • 869 citations

[16] Plasmids of Escherichia coli as cloning vectors

1979 • 655 citations

Identification of genes and gene products necessary for bacterial bioluminescence.

1984 • 615 citations

A large family of bacterial activator proteins.

1988 • 559 citations

Conserved domains in bacterial regulatory proteins that respond to environmental stimuli

1987 • 537 citations

OxyR, a positive regulator of hydrogen peroxide-inducible genes in Escherichia coli and Salmonella typhimurium, is homologous to a family of bacterial regulatory proteins.

1989 • 415 citations

Rapid Mapping of Conditional and Auxotrophic Mutations in Escherichia coli K-12

1973 • 318 citations

The nodD gene of Rhizobium leguminosarum is autoregulatory and in the presence of plant exudate induces the nodA,B,C genes

1985 • 265 citations

Systematic method for the detection of potential λ Cro-like DNA-binding regions in proteins

1987 • 191 citations

Regulatory components in Citrobacter freundii ampC beta-lactamase induction.

1985 • 184 citations

Transfer of Phosphoryl Group between Two Regulatory Proteins Involved in Osmoregulatory Expression of the ompF and ompC Genes in Escherichia coli

1989 • 179 citations

Inducible cephalosporinase production in clinical isolates of Enterobacter cloacae is controlled by a regulatory gene that has been deleted from Escherichia coli.

1986 • 172 citations

Export without proteolytic processing of inner and outer membrane proteins encoded by F sex factor tra cistrons in Escherichia coli minicells.

1979 • 162 citations

A new cell division operon inEscherichia coli

1986 • 156 citations

Nucleotide sequencing and characterization of Pseudomonas putida catR: a positive regulator of the catBC operon is a member of the LysR family

1990 • 154 citations

Inactivation of the ampD gene causes semiconstitutive overproduction of the inducible Citrobacter freundii beta-lactamase

1987 • 150 citations

Binding of the Citrobacter freundii AmpR regulator to a single DNA site provides both autoregulation and activation of the inducible ampC beta-lactamase gene

1989 • 150 citations

A vector for the construction of translational fusions to TEM β-lactamase and the analysis of protein export signals and membrane protein topology

1986 • 146 citations

The nodI gene product of Rhizobium leguminosarum is closely related to ATP-binding bacterial transport proteins; nucleotide sequence analysis of the nodI and nodJ genes

1986 • 134 citations

Transformation ofEscherichia coliC600 by plasmid DNA at different phases of growth

1979 • 124 citations

ampG is essential for high-level expression of AmpC beta-lactamase in Enterobacter cloacae

1989 • 118 citations

Nucleotide sequence and in vivo expression of the ilvY and ilvC genes in Escherichia coli K12. Transcription from divergent overlapping promoters.

1986 • 111 citations

Regulation of diaminopimelate decarboxylase synthesis in Escherichia coli

1983 • 95 citations

Common mechanism of ampC beta-lactamase induction in enterobacteria: regulation of the cloned Enterobacter cloacae P99 beta-lactamase gene

1987 • 93 citations

Regulation of diaminopimelate decarboxylase synthesis in Escherichia coli

1983 • 88 citations

Localization of functional regions of the Rhizobium nodD product using hybrid nodD genes

1989 • 87 citations

Signalling proteins in enterobacterial AmpC β‐lactamase regulation

1989 • 87 citations

Regulation of enterobacterial cephalosporinase production: the role of a membrane‐bound sensory transducer

1989 • 82 citations

Evidence that the transcription activator encoded by the Pseudomonas putida nahR gene is evolutionarily related to the transcription activators encoded by the Rhizobium nodD genes

1989 • 77 citations

Sequence of the Pseudomonas aeruginosa trpI activator gene and relatedness of trpI to other procaryotic regulatory genes

1989 • 74 citations

DNA sequences of the cysB regions of Salmonella typhimurium and Escherichia coli.

1987 • 71 citations

Four classes of mutations in the nodD gene of Rhizobium leguminosarum biovar. viciae that affect its ability to autoregulate and/or activate other nod genes in the presence of flavonoid inducers

1987 • 69 citations

Product of the Lactococcus lactis gene required for malolactic fermentation is homologous to a family of positive regulators

1989 • 66 citations

Resistance of Escherichia coli to penicillins: fine-structure mapping and dominance of chromosomal beta-lactamase mutations

1977 • 65 citations

Regulation of transcription in Escherichia coli from the mer and merR promoters in the transposon Tn501

1989 • 65 citations

Biochemical Genetics of the -Keto Acid Dehydrogenase Complexes of Escherichia coli K12: Isolation and Biochemical Properties of Deletion Mutants

1977 • 62 citations

Interaction between two regulatory proteins in osmoregulatory expression of ompF and ompC genes in Escherichia coli: a novel ompR mutation suppresses pleiotropic defects caused by an envZ mutation

1986 • 59 citations

Nucleotide sequence of the Salmonella typhimurium metR gene and the metR-metE control region

1987 • 56 citations

Purification of the cysB protein from Salmonella typhimurium.

1987 • 52 citations

Coordinate Regulation of β-Lactamase Induction and Peptidoglycan Composition by the Amp Operon

1991 • 51 citations

E. Coli Promoters

1986 • 48 citations

Overexpression and DNA-binding properties of the mer-encoded regulatory protein from plasmid NR1 (Tn21)

1987 • 41 citations

Identification of the DNA binding domain of the phage lambda cII transcriptional activator and the direct correlation of cII protein stability with its oligomeric forms.

1988 • 36 citations