Lack of covalent modification of prostaglandin synthetase (cyclo-oxygenase) by indomethacin

Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs

1971 • 8,596 citations

Acetylation of prostaglandin synthase by aspirin.

1975 • 1,003 citations

The mechanism of the effect of aspirin on human platelets. I. Acetylation of a particulate fraction protein.

1975 • 856 citations

Prostaglandin Synthetase Inhibitors

1977 • 394 citations

Structural requirements for time-dependent inhibition of prostaglandin biosynthesis by anti-inflammatory drugs.

1975 • 288 citations

Properties of a novel preparation of prostaglandin synthetase from sheep seminal vesicles

1971 • 135 citations

Aspirin as a quantitative acetylating reagent for the fatty acid oxygenase that forms prostaglandins

1976 • 71 citations

Anti-Inflammatory Agents

2007 • 14 citations