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A third class of anti‐arrhythmic action. Effects on atrial and ventricular intracellular potentials, and other pharmacological actions on cardiac muscle, of MJ 1999 and AH 3474

Data up to Jan 2025

Published1970
Citations385
References36

Total Citations Per Year

Abstract

References (36)

The biological properties of the optical isomers of propranolol and their effects on cardiac arrhythmias

1968 • 562 citations

The effect of amiodarone, a new anti-anginal drug, on cardiac muscle

1970 • 553 citations

The effect of altered thyroid state on atrial intracellular potentials

1970 • 212 citations

Pharmacological and toxicological properties of two new beta-adrenergic receptor antagonists.

1965 • 208 citations

EVALUATION OF THE CARDIAC EFFECTS OF SEVERAL BETA ADRENERGIC BLOCKING AGENTS

1967 • 205 citations

Cardiac actions in the dog of a new antagonist of adrenergic excitation which does not produce competitive blockade of adrenoceptors

1970 • 180 citations

THE STRUCTURE‐ACTIVITY RELATIONSHIPS OF BETA ADRENERGIC DRUGS AND BETA ADRENERGIC BLOCKING DRUGS

1967 • 131 citations

Membrane depolarization as a cause of tension development in mammalian ventricular muscle

1959 • 119 citations

A comparison of the antiarrhythmic actions of two new synthetic compounds, iproveratril and MJ 1999, with quinidine and pronethalol.

1967 • 96 citations

The relevance of β‐receptor blockade to ouabain‐induced cardiac arrhythmias

1969 • 95 citations

A comparison of the anti‐arrhythmic actions of I.C.I. 50172 and (—)‐propranolol and their effects on intracellular cardiac action potentials and other features of cardiac function

1969 • 79 citations

Myocardial and local anesthetic actions of β-adrenergic receptor blocking drugs: Relationship to physicochemical properties

1968 • 74 citations

Sotalol-Induced Beta Blockade in Cardiac Patients

1970 • 74 citations

The anti-adrenergic action of digitalis on the refractory period of the A-V transmission system.

1961 • 67 citations

Inotropic and metabolic effects of three beta-adrenergic receptor blocking drugs on isolated rabbit left atria.

1965 • 55 citations

Propranolol, MJ 1999 and Ciba 39089 Ba in ouabain and adrenaline induced cardiac arrhythmias

1968 • 51 citations

The effect of bretylium on intracellular cardiac action potentials in relation to its anti‐arrhythmic and local anaesthetic activity

1969 • 48 citations

A comparison of some cardiovascular properties of propranolol, MJ 1999 and quinidine in relation to their effects in hypertensive animals

1968 • 47 citations

Cardiovascular pharmacology of two new beta-adrenergic receptor antagonists.

1965 • 46 citations

A comparative study of some cardiovascular effects of sotalol (MJ 1999) and propranolol

1969 • 45 citations

Sotalol: A new, safe beta adrenergic receptor blocking agent∗

1968 • 42 citations

Local anaesthetic and anti‐arrhythmic actions of alprenolol relative to its effect on intracellular potentials and other properties of isolated cardiac muscle

1970 • 38 citations

Inhibition of cardiac chronotropic action of isoproterenol by Sotalol (MJ 1999) in rat, dog and man.

1967 • 38 citations

CARDIOVASCULAR EFFECTS OF ANOXIA AND THE INFLUENCE OF A NEW BETA ADRENERGIC RECEPTOR BLOCKING DRUG.

1965 • 36 citations

The Effects of Sotalol and Propranolol on Contractile Force and Atrioventricular Conduction Time of the Dog Heart In Situ

1969 • 36 citations

A SIMPLE METHOD FOR RECORDING THE ELECTROCARDIOGRAM AND HEART RATE FROM CONSCIOUS ANIMALS

1968 • 32 citations

Effect of Tetrodotoxin on Membrane Currents in Mammalian Cardiac Fibres

1967 • 30 citations

The Experimental Basis for the Choice of an Anti-arrhythmic Drug

2015 • 26 citations

Comparison of the effects of propranolol and MJ 1999 on cardiac β‐adrenoceptors in man

1970 • 25 citations

Effects on Myocardial Contractility, Hemodynamics and Cardiac Metabolism of a New Beta-Adrenergic Blocking Drug, Sotalol

1969 • 17 citations

The pharmacology of 5-(2-t-butylamino-1-hydroxyethyl) salicylamide (AH 3474), a β-adrenoreceptor blocking agent

1969 • 15 citations

Inhibition of sympathomimetic effects on the cardiovascular system by 4-(2-isopropylamino-1-hydroxyethyl)methanesulfonanilide hydrochloride (MJ 1999).

1967 • 14 citations

Effects of sotalol and propranolol administered orally in man

1969 • 14 citations

The haemodynamic effects of sotalol (MJ 1999) and propranolol in man

1970 • 10 citations

Comparative Actions of Beta-Adrenergic Receptor Blocking Drugs on the Contractile and Electrical Properties of Isolated Human Atrial Muscle

1968 • 5 citations

A nerve-blocking action of MJ-1999.

1969 • 3 citations

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A third class of anti‐arrhythmic action. Effects on atrial and ventricular intracellular… (1970) – British Journal of Pharmacology | Metascience Observatory Explorer