Characterization of an upstream regulatory sequence and its binding protein in the mouse apolipoprotein E gene

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

1993 • 8,888 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology

1988 • 3,984 citations

Affinity purification of sequence-specific DNA binding proteins.

1986 • 1,255 citations

An RNA polymerase II transcription factor binds to an upstream element in the adenovirus major late promoter

1985 • 763 citations

Cell-Specific Expression of the Rat Insulin Gene: Evidence for Role of Two Distinct 5′ Flanking Elements

1985 • 698 citations

A High-Efficiency HeLa Cell Nuclear Transcription Extract

1988 • 612 citations

Apolipoprotein E mRNA is abundant in the brain and adrenals, as well as in the liver, and is present in other peripheral tissues of rats and marmosets.

1985 • 500 citations

Opposing effects of apolipoproteins E and C on lipoprotein binding to low density lipoprotein receptor-related protein.

1990 • 451 citations

Biochemical and genetic studies of the apoprotein E secreted by mouse macrophages and human monocytes.

1982 • 296 citations

Changes of genetic apolipoprotein phenotypes caused by liver transplantation. Implications for apolipoprotein synthesis.

1989 • 253 citations

A far-downstream hepatocyte-specific control region directs expression of the linked human apolipoprotein E and C-I genes in transgenic mice.

1993 • 216 citations

Macrophage free cholesterol content regulates apolipoprotein E synthesis.

1987 • 148 citations

The role of apolipoprotein E in the nervous system

1994 • 139 citations

Expression of heterologous human apolipoprotein E by J774 macrophages enhances cholesterol efflux to HDL3.

1994 • 135 citations

Multiple tissue-specific elements control the apolipoprotein E/C-I gene locus in transgenic mice

1991 • 126 citations

Expression of the human apolipoprotein E gene is regulated by multiple positive and negative elements.

1988 • 120 citations

Cloning and regulation of messenger RNA for mouse apolipoprotein E.

1984 • 84 citations

Regulation of macrophage apolipoprotein E gene expression by cholesterol.

1989 • 83 citations

Apoprotein E is synthesized and secreted by resident and thioglycollate-elicited macrophages but not by pyran copolymer- or bacillus Calmette-Guerin-activated macrophages.

1983 • 80 citations

Identification and characterization of transcriptional regulatory regions associated with expression of the human apolipoprotein E gene.

1988 • 73 citations

Localization of a liver-specific enhancer in the apolipoprotein E/C-I/C-II gene locus

1993 • 58 citations

Characterization of a human apolipoprotein E gene enhancer element and its associated protein factors.

1990 • 54 citations

Structure and Expression of Mouse Apolipoprotein E Grene1

1989 • 40 citations

Regulation of Apolipoprotein E Biosynthesis by cAMP and Phorbol Ester in Rat Ovarian Granulosa Cells

1989 • 38 citations

Apolipoprotein-E messenger RNA in rat ovary is expressed in theca and interstitial cells and presumptive macrophage, but not in granulosa cells.

1992 • 29 citations

Apolipoprotein-E messenger RNA in rat ovary is expressed in theca and interstitial cells and presumptive macrophage, but not in granulosa cells

1992 • 13 citations