Amyloid precursor protein in aged nonhuman primates.

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1987 • 4,544 citations

Amyloid plaque core protein in Alzheimer disease and Down syndrome.

1985 • 4,276 citations

Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesicles

1985 • 1,425 citations

Cleavage of Amyloid β Peptide During Constitutive Processing of Its Precursor

1990 • 1,388 citations

Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein

1989 • 1,237 citations

Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ.

1983 • 1,162 citations

Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

1988 • 1,098 citations

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

1988 • 1,093 citations

A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

1988 • 1,052 citations

Evidence that β-Amyloid Protein in Alzheimer's Disease Is Not Derived by Normal Processing

1990 • 895 citations

Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport.

1990 • 735 citations

Protein p38: an integral membrane protein specific for small vesicles of neurons and neuroendocrine cells.

1986 • 671 citations

Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.

1988 • 584 citations

Conservation of Brain Amyloid Proteins in Aged Mammals and Humans with Alzheimer's Disease

1987 • 472 citations

Formic acid pretreatment enhances immunostaining of cerebral and systemic amyloids.

1987 • 469 citations

The secreted form of the Alzheimer's amyloid precursor protein with the Kunitz domain is protease nexin-II

1989 • 460 citations

Alzheimer's disease amyloidogenic glycoprotein: expression pattern in rat brain suggests a role in cell contact.

1988 • 444 citations

Protease nexin-II, a potent anti-chymotrypsin, shows identity to amyloid β-protein precursor

1989 • 437 citations

Neuritic plaques and cerebrovascular amyloid in Alzheimer disease are antigenically related.

1985 • 431 citations

New Perspectives on Alzheimer's Disease

1986 • 349 citations

Localization of Amyloid β Protein Messenger RNA in Brains from Patients with Alzheimer's Disease

1987 • 297 citations

MOLECULAR BIOLOGY OF ALZHEIMER'S DISEASE

1989 • 266 citations

Biochemistry of Altered Brain Proteins in Alzheimer's Disease

1989 • 261 citations

Amyloid Protein Precursor Messenger RNAs: Differential Expression in Alzheimer's Disease

1988 • 254 citations

Neuronal localization of amyloid beta protein precursor mRNA in normal human brain and in Alzheimer's disease.

1987 • 222 citations

Characterization of an amyloid beta precursor protein that binds heparin and contains tyrosine sulfate.

1989 • 196 citations

In situ hybridization of nucleus basalis neurons shows increased beta-amyloid mRNA in Alzheimer disease.

1988 • 186 citations

Senile plaques in cortex of aged normal monkeys

1985 • 186 citations

Human amyloidosis, Alzheimer disease and related disorders.

1988 • 177 citations

Differential regulation of amyloid-beta-protein mRNA expression within hippocampal neuronal subpopulations in Alzheimer disease.

1988 • 176 citations

Immunocytochemical localization of the precursor protein for β-amyloid in the rat central nervous system

1988 • 153 citations

Evidence for Cholinergic Neurites in Senile Plaques

1984 • 140 citations

Differential expression of amyloid precursor protein mRNAs in cases of Alzheimer's disease and in aged nonhuman primates

1990 • 121 citations

THE IMMUNOHISTOCHEMICAL DEMONSTRATION OF SUBSEQUENCES OF THE PRECURSOR OF THE AMYLOID A4 PROTEIN IN SENILE PLAQUES IN ALZHEIMER'S DISEASE

1989 • 119 citations

CELLULAR LOCALIZATION OF MESSENGER RNA ENCODING AMYLOID-BETA-PROTEIN IN NORMAL TISSUE AND IN ALZHEIMER DISEASE

1988 • 104 citations

Amyloid β-protein precursor accumulates in dystrophic neurites of senile plaques in Alzheimer-type dementia

1990 • 100 citations

Localization of the putative precursor of Alzheimer's disease-specific amyloid at nuclear envelopes of adult human muscle.

1988 • 76 citations

α1-Antichymotrypsin is present together with the β-protein in monkey brain amyloid deposits

1989 • 70 citations

Glutamic acid decarboxylase-like immunoreactive neurites in senile plaques

1985 • 65 citations

Identification of cellular and extracellular sites of amyloid precursor protein extracytoplasmic domain in normal and Alzheimer disease brains.

1989 • 60 citations

Immunohistochemical evidence for the derivation of a peptide ligand from the amyloid beta-protein precursor of Alzheimer disease.

1988 • 56 citations

beta-amyloid protein of Alzheimer's disease is found in cerebral and spinal cord vascular malformations.

1988 • 51 citations

Localization of amyloid beta protein messenger RNA in brains from patients with Alzheimerʼs disease

1988 • 39 citations