CD4+CD45RA+ and CD4+CD45RA− T cell subsets in man maintain distinct function and CD45RA expression persists on a subpopulation of CD45RA+ cells after activation with Con A

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

1985 • 2,257 citations

The differentiation and function of human T lymphocytes

1980 • 1,548 citations

Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells.

1988 • 930 citations

Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN-gamma production.

1988 • 917 citations

The isolation and characterization of the human suppressor inducer T cell subset.

1985 • 860 citations

The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes.

1988 • 716 citations

The isolation and characterization of the human helper inducer T cell subset.

1985 • 708 citations

The Role of the T3/Antigen Receptor Complex in T-Cell Activation

1986 • 627 citations

Functional subsets of human helper-inducer cells defined by a new monoclonal antibody, UCHL1.

1986 • 515 citations

Antigen recognition by human T lymphocytes is linked to surface expression of the T3 molecular complex

1982 • 494 citations

Fluorescent phycobiliprotein conjugates for analyses of cells and molecules.

1982 • 455 citations

The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex.

1989 • 447 citations

The leukocyte common antigen (CD45): a putative receptor-linked protein tyrosine phosphatase.

1988 • 435 citations

Adhesive protein receptors on hematopoietic cells

1988 • 350 citations

Differential usage of three exons generates at least five different mRNAs encoding human leukocyte common antigens.

1987 • 327 citations

Activation of CD4 cells by fibronectin and anti-CD3 antibody. A synergistic effect mediated by the VLA-5 fibronectin receptor complex.

1989 • 291 citations

Differential activation requirements for virgin and memory T cells.

1988 • 271 citations

Ta1, a novel 105 KD human T cell activation antigen defined by a monoclonal antibody.

1984 • 239 citations

CD45 regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T or B cells.

1988 • 223 citations

Loss of CD45R (Lp220) represents a post-thymic T cell differentiation event.

1988 • 218 citations

The functionally distinct subpopulations of human CD4+ helper/inducer T lymphocytes defined by anti-CD45R antibodies derive sequentially from a differentiation pathway that is regulated by activation-dependent post-thymic differentiation.

1988 • 213 citations

Immunoregulatory circuits among T-cell sets. Identification of a subpopulation of T-helper cells that induces feedback inhibition.

1978 • 172 citations

Antibodies to common leukocyte antigen p220 influence human T cell proliferation by modifying IL 2 receptor expression.

1985 • 164 citations

Human lymphocyte differentiation antigens HB-10 and HB-11. II. Differential production of B cell growth and differentiation factors by distinct helper T cell subpopulations.

1985 • 145 citations

Characterization of CD45 and CD45R monoclonal antibodies using transfected mouse cell lines that express individual human leukocyte common antigens.

1988 • 140 citations

Cross-linking of T3 (CD3) with T4 (CD4) enhances the proliferation of resting T lymphocytes.

1987 • 136 citations

Autoantibody to an Immunoregulatory Inducer Population in Patients with Juvenile Rheumatoid Arthritis

1981 • 118 citations

Biochemical Analysis of Membranes

1977 • 117 citations

Induction of suppression following autologous mixed lymphocyte reaction; role of a novel 2H4 antigen

1987 • 111 citations

The subdivision of the T4 (CD4) subset on the basis of the differential expression of L-C/T200 antigens.

1987 • 110 citations

Direct demonstration of the human suppressor inducer subset by anti-T cell antibodies.

1983 • 101 citations

The role of the 2H4 molecule in the generation of suppressor function in Con A-activated T cells.

1986 • 94 citations

Human lymphocyte differentiation antigens HB-10 and HB-11. I. Ontogeny of antigen expression.

1985 • 84 citations

Clonotypic Surface Structure on Human T Lymphocytes: Functional and Biochemical Analysis of the Antigen Receptor Complex

1984 • 83 citations

Triggering of the alternative pathway of human T cell activation involves members of the T 200 family of glycoproteins

1989 • 63 citations

Lymphokine regulation of CD45R expression on human T cell clones.

1989 • 61 citations

The regulation of growth and differentiation of a murine B cell lymphoma. I. Lipopolysaccharide-induced differentiation.

1981 • 57 citations

The cellular basis for the induction of antigen‐specific T8 suppressor cells

1986 • 55 citations

Identification of the sequence required for expression of the 2H4 epitope on the human leukocyte common antigens.

1987 • 51 citations

A human leukocyte antigen identified by a monoclonal antibody

1981 • 49 citations

Generation of CD8 (T8) cytotoxic cells has a preferential requirement for CD4+2H4− inducer cells

1988 • 41 citations

CD4CD45R cells are preferentially activated through the CD2 pathway

1988 • 33 citations

T cell regulation of human B cell proliferation and differentiation. Regulatory influences of CD45R+ and CD45R- T4 cell subsets.

1989 • 33 citations

Functional characterization of the CD45R (2H4) molecule on CD8 (T8) cells in the autologous mixed lymphocyte reaction system

1989 • 32 citations

The T4 molecule differentially regulating the activation of subpopulations of T4+ cells.

1987 • 31 citations

Functional heterogeneity of CD4+ T lymphocytes: two subpopulations with counteracting immunoregulatory functions identified with the monoclonal antibodies WR16 and WR19.

1987 • 31 citations

T lymphocyte depletion of human peripheral blood and bone marrow using monoclonal antibodies and magnetic microspheres.

1987 • 30 citations

The 2H4 molecule but not the T3-receptor complex is involved in suppressor inducer signals in the AMLR system

1987 • 28 citations

Development of an antigen-specific CD8 suppressor effector clone in man.

1988 • 13 citations

Apparent loss of 2H4+ T cells in peripheral blood lymphocytes of normal donors: A 2H4-specific artefact unique to T cells

1988 • 3 citations