Inhibition of endotoxin-induced priming of human neutrophils by lipid X and 3-Aza-lipid X.

Nonparametric Tests Against Trend

1945 • 13,730 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Biological Defense Mechanisms. THE PRODUCTION BY LEUKOCYTES OF SUPEROXIDE, A POTENTIAL BACTERICIDAL AGENT

1973 • 2,955 citations

Control of Cachectin (Tumor Necrosis Factor) Synthesis: Mechanisms of Endotoxin Resistance

1986 • 1,305 citations

Treatment of Gram-Negative Bacteremia and Shock with Human Antiserum to a MutantEscherichia coli

1982 • 1,062 citations

Binding of polymyxin B to the lipid A portion of bacterial lipopolysaccharides

1976 • 818 citations

Modulation of multiple neutrophil functions by preparative methods or trace concentrations of bacterial lipopolysaccharide.

1985 • 796 citations

The Effects of High-Dose Corticosteroids in Patients with Septic Shock

1984 • 761 citations

The microestimation of succinate and the extinction coefficient of cytochrome c

1959 • 751 citations

The role of superoxide anion generation in phagocytic bactericidal activity. Studies with normal and chronic granulomatous disease leukocytes.

1975 • 705 citations

Priming of neutrophils for enhanced release of oxygen metabolites by bacterial lipopolysaccharide. Evidence for increased activity of the superoxide-producing enzyme.

1984 • 612 citations

Gram-negative bacteremia

1980 • 600 citations

Neutrophil-mediated injury to endothelial cells. Enhancement by endotoxin and essential role of neutrophil elastase.

1986 • 576 citations

Steroids in the Treatment of Clinical Septic Shock

1976 • 540 citations

Naloxone reversal of endotoxin hypotension suggests role of endorphins in shock

1978 • 469 citations

PREVENTION OF GRAM-NEGATIVE SHOCK AND DEATH IN SURGICAL PATIENTS BY ANTIBODY TO ENDOTOXIN CORE GLYCOLIPID

1985 • 381 citations

An update on human interleukin-1: From molecular biology to clinical relevance

1985 • 372 citations

Analysis of 1,186 Episodes of Gram-Negative Bacteremia in Non-University Hospitals: The Effects of Antimicrobial Therapy

1983 • 369 citations

Detection of Endotoxin in the Blood of Patients with Sepsis Due to Gram-Negative Bacteria

1970 • 322 citations

Detoxification of Bacterial Lipopolysaccharides (Endotoxins) by a Human Neutrophil Enzyme

1986 • 278 citations

PRESSOR EFFECT OF NALOXONE IN SEPTIC SHOCK

1981 • 214 citations

The activation of protein kinase C by biologically active lipid moieties of lipopolysaccharide.

1984 • 180 citations

Fatty acyl derivatives of glucosamine 1-phosphate in Escherichia coli and their relation to lipid A. Complete structure of A diacyl GlcN-1-P found in a phosphatidylglycerol-deficient mutant.

1983 • 160 citations

MODIFICATION, BY ASPIRIN AND INDOMETHACIN, OF THE HAEMODYNAMIC AND PROSTAGLANDIN RELEASING EFFECTS OF E. coli ENDOTOXIN IN THE DOG

1977 • 107 citations

The biosynthesis of gram-negative endotoxin. Formation of lipid A disaccharides from monosaccharide precursors in extracts of Escherichia coli.

1984 • 104 citations

Gram-Negative-Rod Bacteremia

1974 • 104 citations

Bacterial lipopolysaccharides, phorbol myristate acetate, and zymosan induce the myristoylation of specific macrophage proteins.

1986 • 88 citations

Protection of mice against lethal endotoxemia by a lipid A precursor

1986 • 85 citations

Effects of Bacterial Endotoxins on Neutrophil Function

1985 • 75 citations

The detection of endotoxin by in vitro production of endogenous pyrogen: Comparison with limulus amebocyte lysate gelation

1982 • 74 citations

Characterization of two membrane-associated glycolipids from an Escherichia coli mutant deficient in phosphatidylglycerol.

1981 • 74 citations

Endotoxin-Cell-Membrane Interactions Leading to Transmembrane Signaling

1981 • 73 citations

Macrophage activation by monosaccharide precursors of Escherichia coli lipid A.

1985 • 72 citations

Effect of Polymyxin B Sulfate on Endotoxin Activity in a Gram-Negative Septicemia Model

1979 • 66 citations

Molecular requirements for B-lymphocyte activation by Escherichia coli lipopolysaccharide.

1983 • 63 citations

Glucosamine-derived phospholipids in Escherichia coli. Structure and chemical modification of a triacyl glucosamine 1-phosphate found in a phosphatidylglycerol-deficient mutant.

1983 • 59 citations

STUDIES ON TUBERCULIN FEVER

1965 • 48 citations

The Effects of High-Dose Corticosteroids in Patients with Septic Shock, a Prospective, Controlled Study

1985 • 46 citations

TREATMENT OF GRAM-NEGATIVE BACTEREMIA AND SHOCK WITH HUMAN ANTISERUM TO A MUTANT ESCHERICHIA COLI

1983 • 43 citations

Chemical syntheses of lipid X and lipid Y, acyl glucosamine 1-phosphates isolated from escherichia coli mutants

1984 • 36 citations

Studies on the beneficial effects of Aspirin in endotoxic shock

1983 • 33 citations

Nosocomial Infections in a Community Hospital

1978 • 27 citations

Tables for testing ordered alternatives in an analysis of variance

1977 • 26 citations

Synthesis of biologically active, novel monosaccharide analogs of lipid A.

1984 • 26 citations

Antibiotics and endotoxic shock.

1975 • 25 citations

The Enzymatic Synthesis of Lipid A: Molecular Structure and Biologic Function of Monosaccharide Precursors

1984 • 24 citations

Nosocomial infections in a community hospital: 1972 through 1976

1978 • 23 citations

Mechanism of polymyxin B-mediated lysis of lipopolysaccharide-treated erythrocytes

1985 • 22 citations

Lipopolysaccharide interaction with rabbit erythrocyte membranes

1984 • 19 citations

Endotoxin-initiated membrane changes in rabbit platelets.

1981 • 8 citations

Protection of Mice against Lethal Endotoxemia by a Lipid A Precursor

1986 • 7 citations

Tables for Testing Ordered Alternatives in an Analysis of Variance

1977 • 5 citations