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Porphyrins are endogenous ligands for the mitochondrial (peripheral-type) benzodiazepine receptor.

Data up to Jan 2025

Published1987
Citations297
References28

Total Citations Per Year

Abstract

References (28)

Selective antagonists of benzodiazepines

1981 • 1,235 citations

The peripheral-type benzodiazepine receptor. Localization to the mitochondrial outer membrane.

1986 • 682 citations

Isolation, characterization, and purification to homogeneity of an endogenous polypeptide with agonistic action on benzodiazepine receptors.

1983 • 631 citations

Superinduction of c- fos by Nerve Growth Factor in the Presence of Peripherally Active Benzodiazepines

1985 • 478 citations

Specific high-affinity binding sites for [3H]Ro 5-4864 in rat brain and kidney.

1983 • 296 citations

Benzodiazepine Receptor-Mediated Chemotaxis of Human Monocytes

1985 • 239 citations

Benzodiazepines that bind at peripheral sites inhibit cell proliferation.

1984 • 210 citations

Isolation and characterization of a putative endogenous benzodiazepineoid (endozepine) from bovine and human brain.

1986 • 138 citations

Electrophysiological and pharmacological evidence that peripheral type benzodiazepine receptors are coupled to calcium channels in the heart

1985 • 137 citations

Tranquillizers can block mitogenesis in 3T3 cells and induce differentiation in Friend cells

1980 • 119 citations

Opposite effects of an agonist, R05-4864, and an antagonist, PK 11195, of the peripheral type benzodiazepine binding sites on audiogenic seizures in DBA/2J mice

1984 • 100 citations

The 35 kDa DCCD-binding protein from pig heart mitochondria is the mitochondrial porin

1985 • 87 citations

Differentiation of Friend erythroleukemia cells induced by benzodiazepines.

1984 • 75 citations

Differential mediation of the anticonvulsant effects of carbamazepine and diazepam

1985 • 63 citations

Characterization of the Binding of [3H]Ro 5‐4864, a Convulsant Benzodiazepine, to Guinea Pig Brain

1984 • 63 citations

“Peripheral‐Type”Binding Sites for Benzodiazepines in Brain: Relationship to the Convulsant Actions of Ro 5–4864

1985 • 58 citations

Separation of the coproporphyrin isomers I and III by thin layer chromatography

1963 • 53 citations

Tissue porphyrin pattern determination by high-speed high-performance liquid chromatography

1986 • 51 citations

New endogenous benzodiazepine receptor ligand in human urine: Identity with endogenous monoamine oxidase inhibitor?

1983 • 50 citations

Solubilization and reconstitution of the mitochondrial benzodiazepine receptor

1986 • 49 citations

PK 11195, an antagonist of peripheral benzodiazepine receptors, reduces ventricular arrhythmias during myocardial ischemia and reperfusion in the dog

1985 • 39 citations

Endogenous benzodiazepine receptor agonist in human and mammalian plasma

1986 • 38 citations

Inhibitors of peripheral-type benzodiazepine receptors present in human urine and plasma ultrafiltrates

1983 • 34 citations

Purification and characterization of tribulin, an endogenous inhibitor of monoamine oxidase and of benzodiazepine receptor binding

1986 • 31 citations

Intracellular localization of rat kidney hexokinase. Evidence for an association with low density mitochondria.

1984 • 31 citations

Endogenous inhibitors of 4'‐[3H]chlorodiazepam (Ro 5‐4864) binding to ‘peripheral’ sites for benzodiazepines

1984 • 26 citations

PK 11195, an antagonist of peripheral type benzodiazepine receptors, modulates BAY K8644 sensitive but not β- or H2-receptor sensitive voltage operated calcium channels in the guinea pig heart

1986 • 21 citations

Structure-activity relationship of peptide fragments derived from DBI (diazepam binding inhibitor), a putative endogenous ligand of benzodiazepine recognition sites.

1986 • 7 citations

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Porphyrins are endogenous ligands for the mitochondrial (peripheral-type) benzodiazepine… (1987) – Proceedings of the National Academy of Sciences | Metascience Observatory Explorer