The Effect of Mersalyl on Inositol Trisphosphate Receptor Binding and Ion Channel Function

Inositol trisphosphate and calcium signalling

1993 • 6,546 citations

Bell-shaped calcium-response curves of lns(l,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum

1991 • 1,699 citations

Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400

1989 • 1,039 citations

Calcium as a Coagonist of Inositol 1,4,5-Trisphosphate-Induced Calcium Release

1991 • 843 citations

Putative receptor for inositol 1,4,5-trisphosphate similar to ryanodine receptor

1989 • 531 citations

Purified inositol 1,4,5-trisphosphate receptor mediates calcium flux in reconstituted lipid vesicles

1989 • 512 citations

Block of Ca ²⁺ Wave and Ca ²⁺ Oscillation by Antibody to the Inositol 1,4,5-Trisphosphate Receptor in Fertilized Hamster Eggs

1992 • 493 citations

Structure of a novel InsP3 receptor.

1991 • 383 citations

A diploid epithelial cell line from normal adult rat liver with phenotypic properties of ?oval? cells*1

1984 • 381 citations

Spontaneous calcium release from inositol trisphosphate-sensitive calcium stores

1991 • 366 citations

The ligand binding site and transduction mechanism in the inositol-1,4,5-triphosphate receptor.

1990 • 339 citations

Sequence and functional characterization of a third inositol trisphosphate receptor subtype, IP3R-3, expressed in pancreatic islets, kidney, gastrointestinal tract, and other tissues

1993 • 313 citations

Structural and functional characterization of inositol 1,4,5-trisphosphate receptor channel from mouse cerebellum.

1991 • 299 citations

Calcium-dependent immediate feedback control of inositol 1,4,5-trisphosphate-induced Ca2+ release

1992 • 291 citations

The thiol reagent, thimerosal, evokes Ca2+ spikes in HeLa cells by sensitizing the inositol 1,4,5-trisphosphate receptor.

1992 • 269 citations

The subtypes of the mouse inositol 1,4,5-trisphosphate receptor are expressed in a tissue-specific and developmentally specific manner.

1991 • 262 citations

Three additional inositol 1,4,5-trisphosphate receptors: molecular cloning and differential localization in brain and peripheral tissues.

1992 • 253 citations

Inositol 1,4,5-trisphosphate receptors: distinct neuronal and nonneuronal forms derived by alternative splicing differ in phosphorylation.

1991 • 233 citations

Inositol 1,4,5-trisphosphate receptor

1993 • 178 citations

Determination of relative amounts of inositol trisphosphate receptor mRNA isoforms by ratio polymerase chain reaction.

1994 • 177 citations

Primary structure, ligand binding, and localization of the human type 3 inositol 1,4,5-trisphosphate receptor expressed in intestinal epithelium.

1994 • 173 citations

Oscillatory cytosolic calcium waves independent of stimulated inositol 1,4,5-trisphosphate formation in hepatocytes

1991 • 144 citations

The effect of external calcium and pH on inositol trisphosphate-mediated calcium release from cerebellum microsomal fractions

1989 • 139 citations

Transmembrane topology and sites of N-glycosylation of inositol 1,4,5-trisphosphate receptor.

1994 • 136 citations

Detergent solubility of the inositol trisphosphate receptor in rat brain membranes. Evidence for association of the receptor with ankyrin.

1993 • 130 citations

Calcium mediates the interconversion between two states of the liver inositol 1,4,5-trisphosphate receptor.

1990 • 127 citations

The role of extracellular Ca2+ in the response of the hepatocyte to Ca2+-dependent hormones.

1985 • 117 citations

Sulfhydryl reagents and cAMP-dependent kinase increase the sensitivity of the inositol 1,4,5-trisphosphate receptor in hepatocytes.

1993 • 113 citations

What we can learn from the effects of thiol reagents on transport proteins

1992 • 109 citations

Thiol reagents increase the affinity of the inositol 1,4,5-trisphosphate receptor

1993 • 97 citations

Phosphorylation of the inositol trisphosphate receptor in isolated rat hepatocytes.

1993 • 93 citations

Biphasic effects of cytosolic Ca2+ on Ins(1,4,5)P3-stimulated Ca2+ mobilization in hepatocytes

1993 • 91 citations

Antibody to the inositol trisphosphate receptor blocks thimerosalenhanced Ca²⁺‐induced Ca²⁺ release and Ca²⁺ oscillations in hamster eggs

1992 • 91 citations

Imaging of inositol 1,4,5-trisphosphate-induced Ca2+ fluxes in single permeabilized hepatocytes. Demonstration of both quantal and nonquantal patterns of Ca2+ release.

1993 • 87 citations

Oxidized glutathione causes sensitization of calcium release to inositol 1,4,5-trisphosphate in permeabilized hepatocytes

1992 • 84 citations

Intracellular calcium waves generated by ins(1,4,5)P3-dependent mechanisms

1993 • 83 citations

Phosphorylation of the inositol trisphosphate receptor in isolated rat hepatocytes.

1993 • 80 citations

The effects of thimerosal on calcium uptake and inositol 1,4,5-trisphosphate-induced calcium release in cerebellar microsomes

1993 • 78 citations

SH-group reagents as tools in the study of mitochondrial anion transport

1978 • 77 citations

Hormonal Regulation of Inositol 1,4,5-trisphosphate Receptor in Rat Liver

1989 • 71 citations

Bell-shaped activation of inositol-1,4,5-trisphosphate-induced Ca2+ release by thimerosal in permeabilized A7r5 smooth-muscle cells

1993 • 62 citations

Thimerosal potentiates Ca2+ release mediated by both the inositol 1,4,5-trisphosphate and the ryanodine receptors in sea urchin eggs. Implications for mechanistic studies on Ca2+ signaling

1994 • 46 citations

Characterization of a rapidly dissociating inositol 1,4,5-trisphosphate-binding site in liver membranes.

1992 • 31 citations

The high affinity state of inositol 1,4,5-trisphosphate receptor is a functional state.

1993 • 30 citations

Determination of sulfhydryl groups in ovalbumin by high-performance liquid chromatography with inductively coupled plasma mass spectrometric detection

1993 • 29 citations

Changes in inositol-1, 4, 5-trisphosphate binding to hepatic plasma membranes caused by temperature, N-ethylmaleimide and menadione

1990 • 26 citations

Biosynthesis of the inositol trisphosphate receptor in WB rat liver epithelial cells.

1994 • 19 citations