High titers of inhibitors of von Willebrand factor-cleaving metalloproteinase in a fatal case of acute thrombotic thrombocytopenic purpura

Comparison of Plasma Exchange with Plasma Infusion in the Treatment of Thrombotic Thrombocytopenic Purpura

1991 • 1,836 citations

Antibodies to von Willebrand Factor–Cleaving Protease in Acute Thrombotic Thrombocytopenic Purpura

1998 • 1,749 citations

von Willebrand Factor–Cleaving Protease in Thrombotic Thrombocytopenic Purpura and the Hemolytic–Uremic Syndrome

1998 • 1,630 citations

Physiologic cleavage of von Willebrand factor by a plasma protease is dependent on its conformation and requires calcium ion

1996 • 785 citations

Shear-dependent changes in the three-dimensional structure of human von Willebrand factor

1996 • 598 citations

Shear stress enhances the proteolysis of von Willebrand factor in normal plasma

1994 • 408 citations

Hyalin thrombosis of the terminal arterioles and capillaries : A hitherto undescribed disease

1924 • 356 citations

Identification of a cleavage site directing the immunochemical detection of molecular abnormalities in type IIA von Willebrand factor.

1990 • 347 citations

Acquired Deficiency of von Willebrand Factor-Cleaving Protease in a Patient With Thrombotic Thrombocytopenic Purpura

1998 • 329 citations

Late Relapses in Patients Successfully Treated for Thrombotic Thrombocytopenic Purpura

1995 • 174 citations

Abnormalities of von Willebrand factor multimers in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome.

1989 • 162 citations

Thrombotic thrombocytopenic purpura: a review.

1982 • 146 citations

Hemolytic Uremic Syndrome and Thrombotic Thrombocytopenic Purpura

1993 • 122 citations

Increased von Willebrand factor binding to platelets in single episode and recurrent types of thrombotic thrombocytopenic purpura

1998 • 98 citations

Management of thrombotic thrombocytopenic purpura and hemolytic uremic syndrome.

1997 • 82 citations

Brief report: Resistance development to fluoroquinolones in Europe

1989 • 74 citations

The high molecular weight form of endothelial cell von Willebrand factor is released by the regulated pathway

1991 • 73 citations

Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome relapse: frequency, pathogenesis, and meaning.

1997 • 61 citations

Molecular and cellular biology of von Willebrand factor.

1989 • 57 citations

Increased Fragmentation of von Willebrand Factor, Due to Abnormal Cleavage of the Subunit, Parallels Disease Activity in Recurrent Hemolytic Uremic Syndrome and Thrombotic Thrombocytopenic Purpura and Discloses Predisposition in Families

1999 • 49 citations

HLA‐DR53 protects against thrombotic thrombocytopenic purpura/adult hemolytic uremic syndrome

1994 • 26 citations