Effect of heat shock on RNA metabolism in HeLa cells

A simple, rapid, and sensitive DNA assay procedure

1980 • 5,006 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene.

1975 • 3,483 citations

Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange.

1977 • 2,408 citations

Rapid and efficient cosmid cloning

1981 • 1,897 citations

[68] Transcription maps of polyoma virus-specific RNA: Analysis by two-dimensional nuclease S1 gel mapping

1980 • 1,430 citations

Determination of nucleic acid sequence homologies and relative concentrations by a dot hybridization procedure

1979 • 1,403 citations

Heat shock, from bacteria to man

1982 • 1,260 citations

A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells

1986 • 834 citations

Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma.

1983 • 764 citations

Transcriptional control in the production of liver-specific mRNAs

1981 • 593 citations

RNA splicing is interrupted by heat shock and is rescued by heat shock protein synthesis

1986 • 524 citations

Extreme instability of myc mRNA in normal and transformed human cells.

1984 • 522 citations

Nuclear and nucleolar localization of the 72,000-dalton heat shock protein in heat-shocked mammalian cells.

1984 • 522 citations

Hsp70 accelerates the recovery of nucleolar morphology after heat shock.

1984 • 456 citations

hsp70: Nuclear concentration during environmental stress and cytoplasmic storage during recovery

1984 • 400 citations

Translational control of protein synthesis in response to heat shock in D. melanogaster cells

1980 • 356 citations

Intragenic pausing and anti-sense transcription within the murine c-myc locus.

1986 • 326 citations

Changes in Liver-Specific Compared to Common Gene Transcription During Primary Culture of Mouse Hepatocytes

1983 • 316 citations

Selective inhibition of the synthesis of mitochondria-associated RNA by ethidium bromide

1969 • 312 citations

Induction of thermotolerance and enhanced heat shock protein synthesis in chinese hamster fibroblasts by sodium arsenite and by ethanol

1983 • 306 citations

Regulation of protein synthesis in HeLa cells: Translation at elevated temperatures

1969 • 302 citations

Characterization of a new low molecular weight RNA in HeLa cell ribosomes

1968 • 299 citations

Sequence and organization of genes encoding the human 27 kDa heat shock protein

1986 • 299 citations

Messenger RNA in heat-shocked Drosophila cells

1977 • 292 citations

Patterns of puffing activity in the salivary gland chromosomes of Drosophila

1970 • 270 citations

Analysis of drosophila mRNA by in situ hybridization: Sequences transcribed in normal and heat shocked cultured cells

1975 • 240 citations

Patterns of puffing activity in the salivary gland chromosomes of Drosophila

1969 • 209 citations

Changes in liver-specific compared to common gene transcription during primary culture of mouse hepatocytes.

1983 • 206 citations

Use of peptide tagging to detect proteins expressed from cloned genes: deletion mapping functional domains of Drosophila hsp 70.

1984 • 175 citations

Localization of the heat shock-induced proteins in Drosophila melanogaster tissue culture cells

1980 • 169 citations

Modulation of heat shock polypeptide synthesis in HeLa cells during hyperthermia and recovery

1982 • 162 citations

Selective translation of heat shock mRNA in Drosophila melanogaster depends on sequence information in the leader.

1985 • 160 citations

The Heat Shock Response in HeLa Cells is Accompanied by Elevated Expression of the c-fos Proto-Oncogene

1987 • 147 citations

Chromatin-associated heat shock proteins of Dictyostelium

1982 • 133 citations

Ribosome formation in HeLa cells in the absence of protein synthesis

1966 • 129 citations

Molecular cloning of sequences encoding the human heat-shock proteins and their expression during hyperthermia

1986 • 129 citations

Inhibition of protein synthesis stabilizes histone mRNA.

1984 • 122 citations

Association between the mammalian 110,000-dalton heat-shock protein and nucleoli.

1983 • 121 citations

Two clusters of genes for major chorion proteins of Drosophila melanogaster

1980 • 119 citations

The effect of heat shock on RNA synthesis in Drosophila tissues

1976 • 111 citations

RNA Metabolism in Mammalian Cells at Elevated Temperature

1969 • 109 citations

Regulated transcription of the genes for actin and heat-shock proteins in culture drosophila cells

1981 • 107 citations

The heat shock response in HeLa cells is accompanied by elevated expression of the c-fos proto-oncogene.

1987 • 106 citations

Effect of heat shock on the synthesis of low molecular weight RNAs in drosophila: Accumulation of a novel form of 5S RNA

1975 • 106 citations

The behavior of HeLa-S3 cells under the influence of supranormal temperatures

1971 • 95 citations

Translation in vitro of Drosophila heat-shock messages

1977 • 88 citations

Nuclear metabolism of ribosomal RNA in growing, methionine-limited, and ethionine-treated HeLa cells

1977 • 82 citations

Control of Synthesis and Wastage of Ribosomal Ribonucleic Acid in Lymphocytes

1971 • 71 citations

Structure and processing of precursor 5 S RNA in Drosophila melanogaster

1977 • 66 citations

Heat shock alters nuclear ribonucleoprotein assembly in Drosophila cells.

1983 • 65 citations

RNA metabolism during puff induction in Drosophila melanogaster

1971 • 61 citations

Transcription and metabolism of RNA from the Drosophila melanogaster heat shock puff site 93D

1980 • 57 citations

Expression of intron-containingC. elegansheat shock genes in mouse cells demonstrates divergence of 3' splice site recognition sequences between nematodes and vertebrates, and an inhibitory effect of heat shock on the mammalian splicing apparatus

1987 • 54 citations

Transcription and post-transcriptional regulation of avian HSP70 gene expression.

1986 • 36 citations

Biogenesis of Ribosomes in Eukaryotes

1980 • 27 citations

The Assembly of Ribosomes in HeLa Cell Nucleoli

2005 • 26 citations

Chapter 21. Isolation of Histone Messenger RNA and Its Translationin Vitro

1978 • 9 citations