The human disease network

Network biology: understanding the cell's functional organization

2004 • 7,596 citations

Surfing the p53 network

2000 • 6,487 citations

Lethality and centrality in protein networks

2001 • 5,197 citations

Hierarchical Organization of Modularity in Metabolic Networks

2002 • 4,160 citations

From molecular to modular cell biology

1999 • 3,617 citations

Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders

2004 • 3,142 citations

Towards a proteome-scale map of the human protein–protein interaction network

2005 • 2,923 citations

Genome-wide association studies for common diseases and complex traits

2005 • 2,844 citations

Scale-Free Networks

2003 • 2,439 citations

A Human Protein-Protein Interaction Network: A Resource for Annotating the Proteome

2005 • 2,351 citations

Evidence for dynamically organized modularity in the yeast protein–protein interaction network

2004 • 1,798 citations

Global reconstruction of the human metabolic network based on genomic and bibliomic data

2007 • 1,390 citations

Scale-free networks in cell biology

2005 • 1,206 citations

The Gene Ontology (GO) project in 2006

2005 • 971 citations

A Protein–Protein Interaction Network for Human Inherited Ataxias and Disorders of Purkinje Cell Degeneration

2006 • 776 citations

Scale-Free Networks

2007 • 697 citations

The emerging genetic and molecular basis of Fanconi anaemia

2001 • 578 citations

Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging

2006 • 557 citations

Global topological features of cancer proteins in the human interactome

2006 • 492 citations

Discovering disease-genes by topological features in human protein–protein interaction network

2006 • 453 citations

Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets

2006 • 450 citations

Integrating ‘omic’ information: a bridge between genomics and systems biology

2003 • 440 citations

Dissecting Human Disease in the Postgenomic Era

2001 • 423 citations

Human disease genes

2001 • 383 citations

Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues

2005 • 251 citations

Friendly rivalry

2005 • 201 citations

Peroxisome Biogenesis Disorders

2003 • 197 citations

Interactome modeling

2005 • 98 citations

Characterization and modeling of protein–protein interaction networks

2005 • 91 citations

Topology, tinkering and evolution of the human transcription factor network

2005 • 71 citations

Genetics, Biology and Disease

2000 • 39 citations

An Introduction to Human Molecular Genetics

2005 • 26 citations

Identifying genes and genetic variation underlying human diseases and complex phenotypes via recombination mapping

2003 • 22 citations