Nitric oxide releases intracellular zinc from prokaryotic metallothionein inEscherichia coli

The Galvanization of Biology: A Growing Appreciation for the Roles of Zinc

1996 • 1,857 citations

Femtomolar Sensitivity of Metalloregulatory Proteins Controlling Zinc Homeostasis

2001 • 1,430 citations

Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens

2000 • 1,429 citations

The transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expression.

1994 • 489 citations

The ZnuABC high‐affinity zinc uptake system and its regulator Zur in Escherichia coli

1998 • 464 citations

New functions for the ancient globin family: bacterial responses to nitric oxide and nitrosative stress

2000 • 370 citations

Nitrosative Stress: Activation of the Transcription Factor OxyR

1996 • 351 citations

Direct nitric oxide signal transduction via nitrosylation of iron-sulfur centers in the SoxR transcription activator

2000 • 304 citations

Nitric Oxide Destroys Zinc-Sulfur Clusters Inducing Zinc Release from Metallothionein and Inhibition of the Zinc Finger-Type Yeast Transcription Activator LAC9

1994 • 276 citations

Zap1p, a Metalloregulatory Protein Involved in Zinc-Responsive Transcriptional Regulation in Saccharomyces cerevisiae

1997 • 261 citations

Nitric oxide potentiates hydrogen peroxide-induced killing of Escherichia coli.

1995 • 258 citations

Identification of a Zinc-Specific Metalloregulatory Protein, Zur, Controlling Zinc Transport Operons in Bacillus subtilis

1998 • 256 citations

Metallothionein protects against the cytotoxic and DNA-damaging effects of nitric oxide.

1995 • 243 citations

ZntR is a Zn(II)‐responsive MerR‐like transcriptional regulator of zntA in Escherichia coli

1999 • 242 citations

Nitric oxide, nitrite, and Fnr regulation of hmp (flavohemoglobin) gene expression in Escherichia coli K-12

1996 • 235 citations

Role of metallothionein in nitric oxide signaling as revealed by a green fluorescent fusion protein

2000 • 231 citations

Isolation of a prokaryotic metallothionein locus and analysis of transcriptional control by trace metal ions

1993 • 214 citations

The Zinc-responsive Regulator Zur and Its Control of theznu Gene Cluster Encoding the ZnuABC Zinc Uptake System in Escherichia coli

2000 • 212 citations

DNA Distortion Mechanism for Transcriptional Activation by ZntR, a Zn(II)-responsive MerR Homologue in Escherichia coli

1999 • 195 citations

A metallothionein containing a zinc finger within a four-metal cluster protects a bacterium from zinc toxicity

2001 • 180 citations

An SmtB-like repressor from Synechocystis PCC 6803 regulates a zinc exporter

1998 • 169 citations

Nitric oxide mediates intracytoplasmic and intranuclear zinc release

1997 • 163 citations

Nitric oxide induces Zn2+ release from metallothionein by destroying zinc–sulphur clusters without concomitant formation of S-nitrosothiol

1999 • 123 citations

Inactivation of zinc finger transcription factors provides a mechanism for a gene regulatory role of nitric oxide

2000 • 118 citations

Nitric oxide selectively releases metals from theN‐terminal domain of metallothioneins: potential role at inflammatory sites

2001 • 113 citations

Characterization of the Metal Receptor Sites in Escherichia coli Zur, an Ultrasensitive Zinc(II) Metalloregulatory Protein

2001 • 112 citations

A novel NO‐responding regulator controls the reduction of nitric oxide in Ralstonia eutropha

2000 • 111 citations

Cd(II), Pb(II) and Zn(II) ions regulate expression of the metal‐transporting P‐type ATPase ZntA in Escherichia coli

2000 • 109 citations

Microbial metallothioneins

2001 • 96 citations

[13] Measurement of nitric oxide-mediated effects on zinc homeostasis and zinc finger transcription factors

1999 • 36 citations

Copper-release from yeast Cu(I)-metallothionein by nitric oxide (NO).

2000 • 14 citations