Transforming growth factor-β1 levels are elevated in the striatum and in ventricular cerebrospinal fluid in Parkinson's disease

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Epidermal Growth Factor

1979 • 2,964 citations

Reactive microglia are positive for HLA‐DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

1988 • 2,754 citations

Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo

1995 • 1,084 citations

Interleukin-1 regulates synthesis of nerve growth factor in non-neuronal cells of rat sciatic nerve

1987 • 1,000 citations

TGF-β stimulation and inhibition of cell proliferation: New mechanistic insights

1990 • 992 citations

Tumor necrosis factor-α (TNF-α) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients

1994 • 923 citations

Deactivation of macrophages by transforming growth factor-β

1988 • 876 citations

Interleukin 1 of the central nervous system is produced by ameboid microglia.

1986 • 858 citations

TUMOR NECROSIS, CACHEXIA, SHOCK, AND INFLAMMATION: A COMMON MEDIATOR

1988 • 814 citations

Interleukin-1β, interleukin-6, epidermal growth factor and transforming growth factor-α are elevated in the brain from parkinsonian patients

1994 • 788 citations

Production of tumor necrosis factor and other cytokines by astrocytes stimulated with lipopolysaccharide or a neurotropic virus.

1989 • 785 citations

Astrocytes present myelin basic protein to encephalitogenic T-cell lines

1984 • 773 citations

Physiological Actions and Clinical Applications of Transforming Growth Factor-β (TGF-β)

1993 • 755 citations

Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain

1995 • 659 citations

Negative Regulation of G1 in Mammalian Cells: Inhibition of Cyclin E-Dependent Kinase by TGF-β

1993 • 578 citations

Transforming growth factor-beta 1 in the rat brain: increase after injury and inhibition of astrocyte proliferation

1992 • 486 citations

Brain macrophages: evaluation of microglia and their functions

1992 • 443 citations

Transforming growth factor beta (TGF-?) in inflammation: A cause and a cure

1992 • 417 citations

Differential expression of transforming growth factor-beta 1, -beta 2, and -beta 3 by glioblastoma cells, astrocytes, and microglia.

1992 • 376 citations

Reversible Binding of Nitric Oxide by a Salivary Heme Protein from a Bloodsucking Insect

1993 • 312 citations

Transforming growth factor-beta suppresses activation and proliferation of microglia in vitro.

1993 • 303 citations

Transforming growth factor beta isoforms in the adult rat central and peripheral nervous system

1991 • 303 citations

Macrophage- and astrocyte-derived transforming growth factor beta as a mediator of central nervous system dysfunction in acquired immune deficiency syndrome.

1991 • 295 citations

TGFβ2 and TGFβ3 are potent survival factors for midbrain dopaminergic neurons

1994 • 245 citations

Transforming growth factor-β1 is in plaques in Alzheimer and Down pathologies

1993 • 232 citations

Enhanced expression of transforming growth factor β1 in the rat brain after a localized cerebral injury

1992 • 220 citations

Cooperative regulation of nerve growth factor synthesis and secretion in fibroblasts and astrocytes by fibroblast growth factor and other cytokines

1992 • 207 citations

TGF-β1 mRNA Increases in Macrophage/Microglial Cells of the Hippocampus in Response to Deafferentation and Kainic Acid-Induced Neurodegeneration

1993 • 174 citations

Transforming growth factor-β1 stimulates expression of nerve growth factor in the rat CNS

1990 • 162 citations

Increased transforming growth factor‐β, interleukin‐4, and interferon‐γ in multiple sclerosis

1994 • 162 citations

Transforming growth factor β1 is a potent survival factor for rat embryo motoneurons in culture

1990 • 148 citations

Biochemical neuropathology of Parkinson's disease.

1984 • 116 citations

Transforming growth factor-beta 1 (TGF-β1) expression and regulation in rat cortical astrocytes

1992 • 106 citations

Isoform-Specific Effects of Transforming Growth Factors-? on Degeneration of Primary Neuronal Cultures Induced by Cytotoxic Hypoxia or Glutamate

1993 • 95 citations

Transforming growth factor type β1 modulates the effects of basic fibroblast growth factor on growth and phenotypic expression of rat astroblasts in vitro

1990 • 57 citations

Detection of inactive or less active forms of tyrosine hydroxylase in human adrenals by a sandwich enzyme immunoassay

1984 • 51 citations

Striatal Extracts from Patients with Parkinson's Disease Promote Dopamine Neuron Growth in Mesencephalic Cultures

1993 • 48 citations

Transforming growth factor β (TGF β) in inflammation: a cause and a cure

1992 • 29 citations

Cerebrospinal Fluid from Patients with Parkinson's Disease Alters the Survival of Dopamine Neurons in Mesencephalic Culture

1994 • 26 citations