CpG methylation of promoter region inactivates E‐cadherin gene in renal cell carcinoma

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

1996 • 5,667 citations

Cell Adhesion: The Molecular Basis of Tissue Architecture and Morphogenesis

1996 • 3,454 citations

Cadherin Cell Adhesion Receptors as a Morphogenetic Regulator

1991 • 3,314 citations

Prognostic significance of morphologic parameters in renal cell carcinoma

1982 • 2,700 citations

High sensitivity mapping of methylated cytosines

1994 • 1,863 citations

Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role

1991 • 1,686 citations

E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells.

1991 • 1,592 citations

Spl elements protect a CpG island from de novo methylation

1994 • 713 citations

TNM staging of renal cell carcinoma

1997 • 463 citations

Solution Structure of the Epithelial Cadherin Domain Responsible for Selective Cell Adhesion

1995 • 414 citations

Sp1 transcription factor binds DNA and activates transcription even when the binding site is CpG methylated.

1988 • 308 citations

Abnormal patterns of DNA methylation in human neoplasia: potential consequences for tumor progression.

1991 • 207 citations

Inverse expression of S100A4 and E-cadherin is associated with metastatic potential in gastric cancer.

2000 • 178 citations

Distinct methylation pattern and microsatellite instability in sporadic gastric cancer

1999 • 173 citations

E-cadherin expression as a marker of tumor aggressiveness in routinely processed radical prostatectomy specimens

1999 • 165 citations

E-cadherin expression in renal cell cancer and its significance in metastasis and survival

1995 • 125 citations

METHYLATION OF THE E-CADHERIN GENE PROMOTER CORRELATES WITH PROGRESSION OF PROSTATE CANCER

2001 • 120 citations

Progressive increases in the methylation status and heterochromatinization of the myoD CpG island during oncogenic transformation.

1994 • 74 citations

Expression of cell adhesion molecules alpha-2, alpha-5 and alpha-6 integrin, E-cadherin, N-CAM and CD-44 in renal cell carcinomas

1993 • 39 citations

Paradoxical expression of E‐cadherin in prostatic bone metastases

1999 • 34 citations

Defective E-cadherin function in urological cancers: clinical implications and molecular mechanisms.

1994 • 34 citations

DNA methylation, molecular genetic, and linkage studies in prostate cancer

1996 • 30 citations

Microsatellite instability in an animal model of mammary carcinogenesis.

1998 • 10 citations