Demonstration of strong enterobacterial reactivity of CD4⁺CD25^– T cells from conventional and germ‐free mice which is counter‐regulated by CD4⁺CD25⁺ T cells

A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

1997 • 3,625 citations

CD4+CD25+ Immunoregulatory T Cells Suppress Polyclonal T Cell Activation In Vitro by Inhibiting Interleukin 2 Production

1998 • 2,658 citations

Cytotoxic T Lymphocyte–Associated Antigen 4 Plays an Essential Role in the Function of Cd25+Cd4+ Regulatory Cells That Control Intestinal Inflammation

2000 • 2,211 citations

Immunologic Self-Tolerance Maintained by Cd25+Cd4+Regulatory T Cells Constitutively Expressing Cytotoxic T Lymphocyte–Associated Antigen 4

2000 • 2,207 citations

CD4+CD25+ suppressor T cells: more questions than answers

2002 • 2,202 citations

An Essential Role for Interleukin 10 in the Function of Regulatory T Cells That Inhibit Intestinal Inflammation

1999 • 1,607 citations

Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state.

1998 • 1,579 citations

The Immunology of Mucosal Models of Inflammation

2002 • 1,323 citations

A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells.

1996 • 909 citations

Cutting Edge: Control of CD8+ T Cell Activation by CD4+CD25+ Immunoregulatory Cells

2001 • 743 citations

Ulcerative colitis and adenocarcinoma of the colon in Gαi2-deficient mice

1995 • 416 citations

Reciprocal IFN-γ and TGF-β responses regulate the occurrence of mucosal inflammation

1997 • 399 citations

CD4+ T Cells Reactive to Enteric Bacterial Antigens in Spontaneously Colitic C3H/HeJBir Mice: Increased T Helper Cell Type 1 Response and Ability to Transfer Disease

1998 • 393 citations

Tolerance towards resident intestinal flora in mice is abrogated in experimental colitis and restored by treatment with interleukin‐10 or antibodies to interleukin‐12

1996 • 358 citations

The role of different subsets of T regulatory cells in controlling autoimmunity

2000 • 323 citations

QUANTITATIVE STUDIES ON THE MIXED LYMPHOCYTE INTERACTION IN RATS

1968 • 274 citations

Regulatory T cells and inflammatory bowel disease

1999 • 270 citations

Recent Developments in the Immunology of Inflammatory Bowel Disease

2000 • 206 citations

Spontaneous, heritable colitis in a new substrain of C3H/HeJ mice

1994 • 204 citations

Enteric bacterial antigens activate CD4+ T cells fromscid mice with inflammatory bowel disease

2001 • 90 citations

Oral tolerance in disease

1999 • 88 citations

Colitis-Inducing Potency of CD4+ T Cells in Immunodeficient, Adoptive Hosts Depends on Their State of Activation, IL-12 Responsiveness, and CD45RB Surface Phenotype

1999 • 87 citations

Increased intracellular Th1 cytokines in scid mice with inflammatory bowel disease

1998 • 59 citations

Immune Activation in the Intestinal Mucosa Before the Onset of Colitis in Gαi2‐Deficient Mice

2000 • 54 citations

Functional differentiation of T cells in the intestine of T cell receptor transgenic mice

1997 • 51 citations

Cytotoxic reactivity of gut lamina propria CD4⁺ αβ T cells in SCID mice with colitis

1996 • 43 citations

Proliferation and apoptosis of lamina propria CD4+ T cells from scid mice with inflammatory bowel disease

1998 • 32 citations

Expression of selectin-binding epitopes and cytokines by CD4+ T cells repopulating scid mice with colitis

1998 • 29 citations

CD4+ T regulatory cells from the colonic lamina propria of normal mice inhibit proliferation of enterobacteria-reactive, disease-inducing Th1-cells from scid mice with colitis

2003 • 23 citations

Splenic T helper cell type 1 cytokine profile and extramedullary haematopoiesis in severe combined immunodeficient (scid) mice with inflammatory bowel disease (IBD)

1998 • 23 citations

The majority of lamina propria CD4+ T-cells from scid mice with colitis undergo Fas-mediated apoptosis in vivo

2001 • 11 citations