Cytotoxic activity of an interleukin 6-Pseudomonas exotoxin fusion protein on human myeloma cells.

Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes

1986 • 6,284 citations

A complementation analysis of the restriction and modification of DNA in Escherichia coli

1969 • 3,866 citations

Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells.

1987 • 1,667 citations

The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for the terminal differentiation of B cells.

1988 • 791 citations

Identification of the human 26-kD protein, interferon beta 2 (IFN-beta 2), as a B cell hybridoma/plasmacytoma growth factor induced by interleukin 1 and tumor necrosis factor.

1987 • 690 citations

Molecular Regulation of B Lymphocyte Response

1988 • 579 citations

Structure of exotoxin A of Pseudomonas aeruginosa at 3.0-Angstrom resolution.

1986 • 517 citations

Induction of Neuronal Differentiation in PC12 Cells by B-Cell Stimulatory Factor 2/Interleukin 6

1988 • 402 citations

Human B-cell differentiation factor defined by an anti-peptide antibody and its possible role in autoantibody production.

1987 • 363 citations

Structure and Activity of Diphtheria Toxin

1971 • 352 citations

Receptors for B cell stimulatory factor 2. Quantitation, specificity, distribution, and regulation of their expression.

1987 • 320 citations

Selective killing of HIV-infected cells by recombinant human CD4-Pseudomonas exotoxin hybrid protein

1988 • 253 citations

Activity of a recombinant fusion protein between transforming growth factor type alpha and Pseudomonas toxin.

1987 • 178 citations

Activity of immunotoxins constructed with modified Pseudomonas exotoxin A lacking the cell recognition domain.

1988 • 147 citations

Cytotoxic activity of an interleukin 2-Pseudomonas exotoxin chimeric protein produced in Escherichia coli.

1988 • 133 citations

Exotoxin A of Pseudomonas aeruginosa: substitution of glutamic acid 553 with aspartic acid drastically reduces toxicity and enzymatic activity

1987 • 115 citations

Mutational analysis of domain I of Pseudomonas exotoxin. Mutations in domain I of Pseudomonas exotoxin which reduce cell binding and animal toxicity.

1988 • 87 citations

Role of domain II of Pseudomonas exotoxin in the secretion of proteins into the periplasm and medium by Escherichia coli.

1988 • 69 citations

B Cell Differentiation Factor in Synovial Fluid of Patients with Rheumatoid Arthritis

1984 • 59 citations