Control of the higher eukaryote cell cycle by p34cdc2 homologues

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

Cytoplasmic control of nuclear behavior during meiotic maturation of frog oocytes

1971 • 1,553 citations

Cyclin: A protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division

1983 • 1,506 citations

Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2

1987 • 1,153 citations

Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II

1988 • 1,032 citations

Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog

1987 • 1,004 citations

cdc25+ functions as an inducer in the mitotic control of fission yeast

1986 • 973 citations

The nuclear envelope lamina is reversibly depolymerized during mitosis

1980 • 956 citations

Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe

1976 • 906 citations

Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2+

1988 • 885 citations

Genetic control of cell size at cell division in yeast

1975 • 846 citations

The Xenopus cdc2 protein is a component of MPF, a cytoplasmic regulator of mitosis

1988 • 829 citations

Activation of cdc2 protein kinase during mitosis in human cells: Cell cycle-dependent phosphorylation and subunit rearrangement

1988 • 786 citations

Gene required in G1 for commitment to cell cycle and in G2 for control of mitosis in fission yeast

1981 • 740 citations

Animal Cell Cycle

1978 • 723 citations

cdc2 is a component of the M phase-specific histone H1 kinase: Evidence for identity with MPF

1988 • 535 citations

The clam embryo protein cyclin A induces entry into M phase and the resumption of meiosis in Xenopus oocytes

1986 • 534 citations

The cell cycle control gene cdc2+ of fission yeast encodes a protein kinase potentially regulated by phosphorylation

1986 • 502 citations

Control of Cell Division by Very Lysine Rich Histone (F1) Phosphorylation

1974 • 429 citations

Functionally homologous cell cycle control genes in budding and fission yeast

1982 • 410 citations

Induction of nuclear envelope breakdown, chromosome condensation, and spindle formation in cell-free extracts.

1985 • 407 citations

Phosphorylation of the nuclear lamins during interphase and mitosis.

1985 • 354 citations

Primary structure homology between the product of yeast cell division control gene CDC28 and vertebrate oncogenes

1984 • 354 citations

REGULATORY GENES CONTROLLING MITOSIS IN THE FISSION YEAST SCHIZOSACCHAROMYCES POMBE

1980 • 350 citations

Identification of p34 and p13, human homologs of the cell cycle regulators of fission yeast encoded by cdc2+ and suc1+

1987 • 341 citations

The mitotic inducer nim1+ functions in a regulatory network of protein kinase homologs controlling the initiation of mitosis

1987 • 334 citations

Activation at M-phase of a protein kinase encoded by a starfish homologue of the cell cycle control gene cdc2+

1988 • 314 citations

Sequence of the cell division gene CDC2 from Schizosaccharomyces pombe; patterns of splicing and homology to protein kinases

1984 • 313 citations

Cell division cycle mutants altered in DNA replication and mitosis in the fission yeast Schizosaccharomyces pombe

1981 • 309 citations

Effects of cycloheximide on a cytoplasmic factor initiating meiotic maturation in Xenopus oocytes

1975 • 294 citations

Human cdc2 protein kinase is a major cell-cycle regulated tyrosine kinase substrate

1988 • 285 citations

Changes in protein phosphorylation accompanying maturation of Xenopus laevis oocytes

1977 • 269 citations

Induction of early mitotic events in a cell-free system

1985 • 263 citations

Characterization of insulin-stimulated microtubule-associated protein kinase. Rapid isolation and stabilization of a novel serine/threonine kinase from 3T3-L1 cells.

1988 • 257 citations

Phosphorylation of Very‐Lysine‐Rich Histone in Physarum polycephalum

1973 • 250 citations

Altered phosphorylation and activation of PP60c-src during fibroblast mitosis

1988 • 249 citations

A bifunctional gene product involved in two phases of the yeast cell cycle

1982 • 225 citations

The fission yeast cell cycle control gene cdc2: isolation of a sequence suc1 that suppresses cdc2 mutant function

1986 • 222 citations

Cloning and sequencing of the cyclin-related Cdc13 + gene and a cytological study of its role in fission yeast mitosis

1988 • 220 citations

Generality of the action of various maturation-promoting factors

1982 • 195 citations

Regulated expression and phosphorylation of a possible mammalian cell-cycle control protein

1988 • 189 citations

Dual regulation of the yeast CDC28-p40 protein kinase complex: Cell cycle, pheromone, and nutrient limitation effects

1987 • 166 citations

The effect of puromycin on protein metabolism and cell division in fertilized sea urchin eggs

1961 • 160 citations

Initiation of mitosis in relation to the cell division cycle

1962 • 153 citations

Control of the yeast cell cycle is associated with assembly/disassembly of the Cdc28 protein kinase complex

1988 • 148 citations

PHO85, a negative regulator of the PHO system, is a homolog of the protein kinase gene, CDC28, of Saccharomyces cerevisiae

1988 • 141 citations

Activity of the maturation-promoting factor and the extent of protein phosphorylation oscillate simultaneously during meiotic maturation of starfish oocytes

1983 • 137 citations

The Relationship of Histone Phosphorylation to Deoxyribonucleic Acid Replication and Mitosis during the HeLa S-3 Cell Cycle

1973 • 131 citations

Role of protein synthesis and proteases in production and inactivation of maturation-promoting activity during meiotic maturation of starfish oocytes

1985 • 104 citations

F1-histone modification at metaphase in Chinese hamster cells

1972 • 101 citations

Genetic nomenclature and gene list of the fission yeast Schizosaccharomyces pombe

1987 • 95 citations

Hormonal control of reinitiation of meiosis in starfish

1975 • 85 citations

An M-phase-specific protein kinase of Xenopus oocytes: Partial purification and possible mechanism of its periodic activation

1988 • 85 citations

Chapter 13. Methods for the Assessment of Site-Specific Histone Phosphorylation

1978 • 74 citations

G2-population cells in mouse kidney and duodenum and their behavior during the cell division cycle

1970 • 73 citations

The metabolism of histone fractions

1973 • 70 citations

Induction of starfish oocyte maturation by maturation‐promoting factor of mouse and surf clam oocytes

1984 • 62 citations

Changes in the Activity of the Maturation‐Promoting Factor Are Correlated with Those of a Major Cyclic AMP and Calcium‐Independent Protein Kinase During the First Mitotic Cell Cycles in the Early Starfish Embryo

1987 • 53 citations

Preliminary characterization of maturation-promoting factor from yeast Saccharomyces cerevisiae *

1987 • 52 citations

Two-dimensional polyacrylamide gel analysis of changes in protein phosphorylation during maturation of Xenopus oocytes

1985 • 51 citations

Synthesis of protein for DNA replication and cleavage events in the sand dollar embryo

1969 • 43 citations

Calcium‐ and Cyclic AMP‐independent, Labile Protein Kinase Appearing during Starfish Oocyte Maturation: its Extraction and Partial Characterization*

1985 • 38 citations

H1 histone kinases from nuclei of Physarum polycephalum

1983 • 25 citations

Multiple phosphorylated forms of the product of the fission yeast cell division cycle gene cdc2 +

1988 • 18 citations

Does the M‐Phase Promoting Factor (MPF) Activate a Major Ca²⁺‐and Cyclic Nucleotide‐Independent Protein Kinase in Starfish Ocytes?

1988 • 7 citations