A phase II trial of imatinib mesylate monotherapy in patients with metastatic breast cancer

New Guidelines to Evaluate the Response to Treatment in Solid Tumors

2000 • 15,583 citations

Cell Signaling by Receptor Tyrosine Kinases

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Untangling the ErbB signalling network

2001 • 6,623 citations

Efficacy and Safety of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in Chronic Myeloid Leukemia

2001 • 5,189 citations

Cell Signaling by Receptor Tyrosine Kinases

2000 • 3,570 citations

Activity of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in the Blast Crisis of Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia with the Philadelphia Chromosome

2001 • 2,749 citations

Effect of the Tyrosine Kinase Inhibitor STI571 in a Patient with a Metastatic Gastrointestinal Stromal Tumor

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The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

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Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumours: a phase I study

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Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor

2000 • 1,038 citations

Mutations in Exons 9 and 13 of KIT Gene Are Rare Events in Gastrointestinal Stromal Tumors

2000 • 308 citations

Update of phase I study of imatinib (STI571) in advanced soft tissue sarcomas and gastrointestinal stromal tumors: a report of the EORTC Soft Tissue and Bone Sarcoma Group

2002 • 231 citations

BCR/ABL Regulates Expression of the Cyclin-dependent Kinase Inhibitor p27Kip1 through the Phosphatidylinositol 3-Kinase/AKT Pathway

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STI571: A Paradigm of New Agents for Cancer Therapeutics

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Coexpression of the c-kit and stem cell factor genes in breast carcinomas.

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KIT (CD117)-Positive Breast Cancers Are Infrequent and Lack KIT Gene Mutations

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Role for the Adaptor Protein Grb10 in the Activation of Akt

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Localization of platelet-derived growth factor beta receptor expression in the periepithelial stroma of human breast carcinoma.

1996 • 83 citations

STI571: A Paradigm of New Agents for Cancer Therapeutics

2002 • 80 citations

Expression of C-KIT and HER-2 tyrosine kinase receptors in poor-prognosis breast cancer.

2002 • 37 citations

Deleted Work

1955 • 0 citations