Molecular profiles as predictive marker for the effect of overall treatment time of radiotherapy in supraglottic larynx squamous cell carcinomas

The hazard of accelerated tumor clonogen repopulation during radiotherapy

1988 • 1,592 citations

A radiation therapy oncology group (RTOG) phase III randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas: first report of RTOG 9003

2000 • 1,352 citations

Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck.

1999 • 707 citations

Molecular classification of head and neck squamous cell carcinomas using patterns of gene expression

2004 • 659 citations

Five compared with six fractions per week of conventional radiotherapy of squamous-cell carcinoma of head and neck: DAHANCA 6&7 randomised controlled trial

2003 • 645 citations

Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of β-catenin, and enhanced tumor cell invasion

2003 • 631 citations

Review of the literature and a recommended system of malignancy grading in oral squamous cell carcinomas

1987 • 532 citations

A randomised multicentre trial of CHART versus conventional radiotherapy in head and neck cancer

1997 • 477 citations

Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation

1997 • 416 citations

Evidence that cadherins play a role in the downregulation of integrin expression that occurs during keratinocyte terminal differentiation

1994 • 223 citations

Randomized clinical trial on 7-day-continuous accelerated irradiation (CAIR) of head and neck cancer – report on 3-year tumour control and normal tissue toxicity

2000 • 162 citations

A randomised trial of accelerated versus conventional radiotherapy in head and neck cancer

1997 • 159 citations

Importance of overall treatment time for the outcome of radiotherapy of advanced head and neck carcinoma: dependency on tumor differentiation

1997 • 149 citations

The prognostic value of epidermal growth factor receptor is related to tumor differentiation and the overall treatment time of radiotherapy in squamous cell carcinomas of the head and neck

2004 • 104 citations

Evaluation of malignancy and the prognosis of esophageal cancer based on an immunohistochemical study (p53, E-cadherin, epidermal growth factor receptor)

1999 • 87 citations

Molecular Marker Profiles Predict Locoregional Control of Head and Neck Squamous Cell Carcinoma in a Randomized Trial of Continuous Hyperfractionated Accelerated Radiotherapy

2004 • 86 citations

Altered E-cadherin and epidermal growth factor receptor expressions are associated with patient survival in lung cancer: a study utilizing high-density tissue microarray and immunohistochemistry

2004 • 69 citations

A multicentre randomized/controlled trial of a conventional versus modestly accelerated radiotherapy in the laryngeal cancer: influence of a 1 week shortening overall time

2002 • 62 citations

bcl-2 expression in head and neck cancer: an enigmatic prognostic marker

2001 • 55 citations

Molecular markers in clinical radiation oncology

2003 • 46 citations

Histological grading of epidermoid carcinomas in the head and neck.

1977 • 32 citations

Acute and late normal tissue reactions in the DAHANCA 6&7 randomized trial with accelerated radiotherapy for head and neck cancer

2003 • 8 citations