Epstein-Barr Virus DNA Recombination and Loss in Sporadic Burkitt's Lymphoma

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Cellular localization of an Epstein‐Barr virus (EBV)‐associated complement‐fixing antigen in producer and non‐producer lymphoblastoid cell lines

1973 • 1,718 citations

The structure of the termini of the Epstein-Barr virus as a marker of clonal cellular proliferation

1986 • 927 citations

Detection of Epstein–Barr Viral Genomes in Reed–Sternberg Cells of Hodgkin's Disease

1989 • 917 citations

A cis-acting element from the Epstein-Barr viral genome that permits stable replication of recombinant plasmids in latently infected cells.

1984 • 685 citations

CYTOLOGY OF BURKITT'S TUMOUR (AFRICAN LYMPHOMA)

1964 • 627 citations

Sequence-specific DNA binding of the Epstein-Barr virus nuclear antigen (EBNA-1) to clustered sites in the plasmid maintenance region

1985 • 502 citations

The Association of Epstein–Barr Virus with Smooth-Muscle Tumors Occurring after Organ Transplantation

1995 • 471 citations

Activation of expression of latent Epstein-Barr herpesvirus after gene transfer with a small cloned subfragment of heterogeneous viral DNA.

1985 • 454 citations

Both Epstein-Barr virus (EBV)-encoded trans-acting factors, EB1 and EB2, are required to activate transcription from an EBV early promoter.

1986 • 359 citations

The oncogenic potential of herpes simplex viruses: evidence for a ‘hit-and-run’ mechanism

1983 • 313 citations

Isolation of Epstein-Barr virus (EBV)-negative cell clones from the EBV-positive Burkitt's lymphoma (BL) line Akata: malignant phenotypes of BL cells are dependent on EBV

1994 • 286 citations

Differences Between Laboratory Strains of Epstein-Barr Virus Based on Immortalization, Abortive Infection, and Interference

1974 • 279 citations

trans activation of the latent Epstein-Barr virus (EBV) genome after transfection of the EBV DNA fragment

1986 • 278 citations

Cross‐linking of cell surface immunoglobulins induces epstein‐barr virus in burkitt lymphoma lines

1984 • 253 citations

Functional and physical interaction between p53 and BZLF1: implications for Epstein-Barr virus latency.

1994 • 242 citations

Differentiation-associated expression of the Epstein-Barr virus BZLF1 transactivator protein in oral hairy leukoplakia

1991 • 234 citations

Restricted expression of EBV latent genes and T-lymphocyte-detected membrane antigen in Burkitt's lymphoma cells.

1986 • 201 citations

Epstein-Barr virus RNA. V. Viral RNA in a restringently infected, growth-transformed cell line

1980 • 175 citations

Persistence of the Entire Epstein-Barr Virus Genome Integrated into Human Lymphocyte DNA

1984 • 156 citations

Absence of Epstein-Barr Viral DNA in American Burkitt's Lymphoma

1973 • 144 citations

Transfection of a rearranged viral DNA fragment, WZhet, stably converts latent Epstein-Barr viral infection to productive infection in lymphoid cells.

1987 • 136 citations

Epstein-Barr virus with heterogeneous DNA disrupts latency

1984 • 128 citations

Identification of a rare Epstein-Barr virus variant that enhances early antigen expression in Raji cells.

1983 • 116 citations

Episomal and integrated copies of Epstein-Barr virus coexist in Burkitt lymphoma cell lines

1993 • 104 citations

Genome rearrangements activate the Epstein-Barr virus gene whose product disrupts latency.

1988 • 100 citations

Epstein-barr virus integration in human lymphomas and lymphoid cell lines

1992 • 93 citations

Structure and role of the terminal repeats of Epstein-Barr virus in processing and packaging of virion DNA

1995 • 82 citations

Epstein-Barr virus induction of recombinase-activating genes RAG1 and RAG2

1995 • 75 citations

The prototypical Epstein-Barr virus-transformed lymphoblastoid cell line IB4 is an unusual variant containing integrated but no episomal viral DNA

1991 • 66 citations

Antigenic and Sequence Variation in the C-Terminal Unique Domain of the Epstein-Barr Virus Nuclear Antigen EBNA-1

1995 • 63 citations

Epstein-Barr virus intrastrain recombination in oral hairy leukoplakia

1994 • 61 citations

Defective viral DNA in Epstein-Barr virus-associated oral hairy leukoplakia

1990 • 59 citations

Expression of recombination activating genes (RAG-1 and RAG-2) in Epstein-Barr virus-bearing B cells [see comments]

1995 • 56 citations

Structure of defective DNA molecules in Epstein-Barr virus preparations from P3HR-1 cells

1984 • 49 citations

Thymic Carcinoma with a Defective Epstein-Barr Virus Encoding the BZLFI trans-Activator

1994 • 42 citations

P3HR-1 Epstein-Barr virus with heterogeneous DNA is an independent replicon maintained by cell-to-cell spread

1985 • 42 citations

Sequences of the Epstein-Barr Virus (EBV) large internal repeat form the center of a 16-kilobase-pair palindrome of EBV (P3HR-1) heterogeneous DNA

1987 • 39 citations

Polymorphisms of the region of the Epstein-Barr virus genome which disrupts latency

1988 • 38 citations

Biochemical Characterization of Epstein-Barr Virus Nuclear Antigen 3A and 3C Proteins

1994 • 23 citations

Partial elimination of Epstein-Barr virus plasmids from Burkitt's lymphoma cells by transfecting the BZLF1 gene

1992 • 15 citations

Epstein-Barr virus DNA recombines via latent origin of replication with the human genome in the lymphoblastoid cell line RGN1

1992 • 13 citations

Autoantigenic proteins that bind recombinogenic sequences in Epstein-Barr virus and cellular DNA.

1994 • 13 citations

Human Oropharyngeal Lesions with a Defective Epstein-Barr Virus that Disrupts Viral Latency

1993 • 10 citations

An EBNA-negative, EBV-genome-positive human lymphoblast cell line in which superinfecting EBV DNA is not maintained

1984 • 7 citations

Integration of a short Epstein--Barr virus DNA fragment in a B95-8 virus converted Burkitt lymphoma line expressing Epstein--Barr nuclear antigens EBNA2 and EBNA5

1993 • 6 citations

Epstein–Barr Virus: Molecular Biology

2008 • 4 citations