Induction of tumor necrosis factor-α mRNA in the brain after peripheral endotoxin treatment: comparison with interleukin-1 family and interleukin-6

The Biology of Cachectin/TNF -- A Primary Mediator of the Host Response

1989 • 1,679 citations

Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1.

1986 • 1,501 citations

Circulating Interleukin-1 and Tumor Necrosis Factor in Septic Shock and Experimental Endotoxin Fever

1990 • 765 citations

Correlation of interleukin-1β and cachectin concentrations in cerebrospinal fluid and outcome from bacterial meningitis

1989 • 278 citations

Brain interleukin 1 gene expression induced by peripheral lipopolysaccharide administration

1992 • 217 citations

Intrinsic Pituitary Interleukin-1β Is Induced by Bacterial Lipopolysaccharide**

1990 • 142 citations

Detection of cytokine mRNA in astrocyte cultures using the polymerase chain reaction.

1990 • 112 citations

Endotoxin-induced cytokine gene expression in vivo. II. Regulation of tumor necrosis factor and interleukin-1 alpha/beta expression and suppression.

1990 • 109 citations

Kinetics of cytokine mRNA production in the brains of mice with progressive toxoplasmic encephalitis

1992 • 109 citations

Tumor necrosis factor-α gene expression in the tissues of normal mice

1992 • 79 citations

Cloning and expression in Escherichia coli of the gene for rat tumor necrosis factor.

1989 • 60 citations

Intracerebral Synthesis of Tumor Necrosis Factor‐α and Interleukin‐6 in Infectious Meningitisa

1990 • 34 citations

Cellular Sources and Effects of Tumor Necrosis Factor‐α on Pituitary Cells and in the Central Nervous Systema

1990 • 21 citations