Molecular biology and genetics of gap junction channels

CLUSTAL: a package for performing multiple sequence alignment on a microcomputer

1988 • 3,446 citations

Connexin43: a protein from rat heart homologous to a gap junction protein from liver.

1987 • 1,111 citations

Molecular cloning of cDNA for rat liver gap junction protein.

1986 • 715 citations

Structure of the junction between communicating cells

1980 • 697 citations

A FINE STRUCTURAL ANALYSIS OF INTERCELLULAR JUNCTIONS IN THE MOUSE LIVER

1970 • 626 citations

Connexin46, a novel lens gap junction protein, induces voltage-gated currents in nonjunctional plasma membrane of Xenopus oocytes.

1991 • 600 citations

Connexin family of gap junction proteins

1990 • 553 citations

Antisera directed against connexin43 peptides react with a 43-kD protein localized to gap junctions in myocardium and other tissues.

1989 • 516 citations

Gap junction structures: Analysis of the x-ray diffraction data

1977 • 501 citations

Cloning and characterization of human and rat liver cDNAs coding for a gap junction protein.

1986 • 443 citations

Sequence and tissue distribution of a second protein of hepatic gap junctions, Cx26, as deduced from its cDNA.

1989 • 427 citations

Transfection of C6 glioma cells with connexin 43 cDNA: analysis of expression, intercellular coupling, and cell proliferation.

1991 • 366 citations

Expression of the gap junction protein connexin43 in embryonic chick lens: Molecular cloning, ultrastructural localization, and post-translational phosphorylation

1990 • 358 citations

Comparative characterization of the 21-kD and 26-kD gap junction proteins in murine liver and cultured hepatocytes.

1989 • 341 citations

Gap junctions formed by connexins 26 and 32 alone and in combination are differently affected by applied voltage.

1991 • 340 citations

Topology of the 32-kd liver gap junction protein determined by site-directed antibody localizations.

1988 • 327 citations

Formation of gap junctions by expression of connexins in Xenopus oocyte pairs

1989 • 317 citations

Four novel members of the connexin family of gap junction proteins. Molecular cloning, expression, and chromosome mapping.

1992 • 305 citations

Two homologous protein components of hepatic gap junctions

1987 • 284 citations

Tyrosine phosphorylation of the gap junction protein connexin43 is required for the pp60v-src-induced inhibition of communication.

1990 • 276 citations

Modulation of gap junction transcript and protein expression during pregnancy in the rat.

1990 • 259 citations

Cardiac myocytes express multiple gap junction proteins.

1992 • 234 citations

Ryanodine Receptor of Skeletal Muscle Is a Gap Junction-Type Channel

1988 • 231 citations

The diversity of connexin genes encoding gap junctional proteins.

1991 • 230 citations

Structure and biochemistry of mouse hepatic gap junctions

1979 • 228 citations

Isolation and characterization of gap junctions from rat liver.

1979 • 228 citations

The 43-kD polypeptide of heart gap junctions: immunolocalization, topology, and functional domains.

1989 • 224 citations

Topological analysis of the major protein in isolated intact rat liver gap junctions and gap junction-derived single membrane structures.

1987 • 205 citations

Molecular characterization and functional expression of the human cardiac gap junction channel.

1990 • 201 citations

Topological distribution of two connexin32 antigenic sites in intact and split rodent hepatocyte gap junctions.

1988 • 199 citations

A detergent-independent procedure for the isolation of gap junctions from rat liver.

1984 • 179 citations

Distribution of mRNAs coding for liver and heart gap junction proteins in the rat central nervous system

1991 • 178 citations

Mouse connexin37: cloning and functional expression of a gap junction gene highly expressed in lung.

1991 • 172 citations

Expression of Functional Cell-Cell Channels from Cloned Rat Liver Gap Junction Complementary DNA

1987 • 166 citations

Cloning and Expression of a Xenopus Embryonic Gap Junction Protein

1989 • 161 citations

Formation of hybrid cell-cell channels.

1989 • 160 citations

Homologies between gap junction proteins in lens, heart and liver

1988 • 160 citations

Expression of gap junction channels in communication-incompetent cells after stable transfection with cDNA encoding connexin 32.

1990 • 142 citations

Differential regulation of the levels of three gap junction mRNAs in Xenopus embryos.

1990 • 135 citations

Molecular cloning and developmental expression of two chick embryo gap junction proteins.

1990 • 131 citations

Isolation and purification of gap junction channels.

1991 • 126 citations

Developmental regulation of gap junction gene expression during mouse embryonic development

1991 • 125 citations

Topology of the Mr 27,000 liver gap junction protein. Cytoplasmic localization of amino- and carboxyl termini and a hydrophilic domain which is protease-hypersensitive.

1988 • 119 citations

The human connexin gene family of gap junction proteins: Distinct chromosomal locations but similar structures

1991 • 118 citations

Expression of different connexin genes in rat uterus during decidualization and at term.

1991 • 115 citations

Sequence and developmental expression of mRNA coding for a gap junction protein in Xenopus.

1988 • 103 citations

Molecular cloning and characterization of a new member of the gap junction gene family, connexin-31.

1991 • 102 citations

Structure of a gap junction gene: Rat connexin-32

1988 • 100 citations

Topography of connexin32 in rat liver gap junctions : Evidence for an intramolecular disulphide linkage connecting the two extracellular peptide loops

1991 • 90 citations

Six genes of the human connexin gene family coding for gap junctional proteins are assigned to four different human chromosomes.

1990 • 88 citations

Gap junction protein in rat hippocampus: Light microscope immunohistochemical localization

1989 • 73 citations

Spatiotemporal expression of three gap junction gene products involved in fetomaternai communication during rat pregnancy

1991 • 72 citations

Maize mesocotyl plasmodesmata proteins cross-react with connexin gap junction protein antibodies.

1991 • 71 citations

Cell biology: Is there a common design for cell membrane channels?

1986 • 60 citations

Connexon integrity is maintained by non-covalent bonds: Intramolecular disulfide bonds link the extracellular domains in rat connexin-43

1991 • 60 citations

Expression of gap junction genes during postnatal neural development

1991 • 57 citations

Gap junction protein homologue from Arabidopsis thaliana: evidence for connexins in plants.

1991 • 52 citations

Distribution of genes for gap junction membrane channel proteins on human and mouse chromosomes

1991 • 50 citations

Diffraction diagnosis of protein folding in gap junction connexons

1990 • 48 citations

Translation and functional expression of cell-cell channel mRNA inXenopus oocytes

1985 • 47 citations

Proteolysis of cardiac gap junctions during their isolation from rat hearts

1985 • 47 citations

Molecular cloning of a rat uterine gap junction protein and analysis of gene expression during gestation

1991 • 44 citations

Rat heart gap junctions as disulfide-bonded connexon multimers: Their depolymerization and solubilization in deoxycholate

1986 • 43 citations

Gap Junction Structures

1982 • 42 citations

Identification of a rat liver cDNA and mRNA coding for the 28 kDa gap junction protein

1986 • 39 citations

The secondary structure of gap junctions. Influence of isolation methods and proteolysis.

1990 • 36 citations

Cellular localization of gap junction mRNA in the neonatal rat brain

1991 • 33 citations

Cell-to-Cell Communication

1986 • 29 citations

Androgen regulates gap junction mRNA expression in androgen-sensitive motoneurons in the rat spinal cord

1991 • 28 citations