Misoprostol prevents damage to the gastric mucosa by stabilizing the mast cells

Cytoprotection by prostaglandins in rats

1979 • 1,698 citations

A Sensitive and Specific Method for the Determination of Histamine in Human Whole Blood and Plasma

1972 • 242 citations

Prostaglandin Protection of the Gastric Mucosa Against Alcohol Injury—A Dynamic Time-Related Process

1985 • 207 citations

Prostaglandin cytoprotection of gastric mucosa

1978 • 199 citations

Gastrointestinal cytoprotection by prostaglandins.

1979 • 190 citations

Morphology of Rat Gastric Mucosal Damage, Defense, and Restitution in the Presence of Luminal Ethanol

1985 • 150 citations

A double-blind study of prophylactic effect of misoprostol on lesions of gastric and duodenal mucosa induced by oral administration of tolmetin in healthy subjects

1986 • 101 citations

Effect of synthetic prostaglandin E1 analog on aspirin-induced gastric bleeding and secretion

1983 • 88 citations

SC-29333: A potent inhibitor of canine gastric secretion

1976 • 74 citations

Gastric protection by misoprostol against 1300 mg of aspirin

1986 • 73 citations

Effects of misoprostol on gastric acid and mucus secretion in man

1986 • 71 citations

A multicenter international controlled comparison of two dosage regimens of misoprostol with cimetidine in treatment of gastric ulcer in outpatients

1986 • 65 citations

Healing of benign gastric ulcer

1985 • 64 citations

Misoprostol preclinical pharmacology

1985 • 60 citations

Effects of E prostaglandins on canine gastric potential difference

1978 • 55 citations

Misoprostol in the treatment of duodenal ulcer

1985 • 50 citations

Efficacy of misoprostol (twice daily dosage) in acute healing of duodenal ulcer

1986 • 49 citations

Effects of a prostaglandin E1 derivative, SC-29333, and aspirin on gastric ionic fluxes and potential difference in dogs.

1979 • 46 citations

Inhibition of nocturnal gastric secretion in normal human volunteers by misoprostol: a synthetic prostaglandin E1 methyl ester analog.

1982 • 44 citations

Cytoprotection by a synthetic prostaglandin against ethanol-induced gastric mucosal damage

1986 • 43 citations

The cytoprotective effects of (±)-15-deoxy-16-α,β-hydroxy-16-methyl PGE1 methyl ester (SC-29333) versus aspirin-shock gastric ulcerogenesis in the dog

1981 • 43 citations

Misoprostol clinical pharmacology

1985 • 42 citations

Histamine content and mast cells in human gastric and duodenal mucosa

1978 • 37 citations

Gastrointestinal cytoprotective effects of misoprostol

1985 • 32 citations

Duodenal bicarbonate secretion in humans

1986 • 31 citations

Effect of SC-29333, an inhibitor of gastric secretion, on canine gastric mucosal blood flow and serum gastrin levels.

1978 • 25 citations