Cholecystokinin-induced anxiety: How is it reflected in studies on exploratory behaviour?

Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

1985 • 5,596 citations

Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.

1988 • 4,617 citations

A psychomotor stimulant theory of addiction.

1987 • 2,704 citations

Chemical Neuroanatomy

1984 • 1,646 citations

Effects of alpha-adrenoceptor agonists and antagonists in a maze-exploration model of ?fear?-motivated behaviour

1984 • 951 citations

The relation between fear induced by novel stimulation and exploratory drive.

1955 • 900 citations

Different populations of GABAergic neurons in the visual cortex and hippocampus of cat contain somatostatin- or cholecystokinin- immunoreactive material

1984 • 733 citations

Two brain cholecystokinin receptors: implications for behavioral actions

1986 • 719 citations

Evidence for coexistence of dopamine and CCK in meso-limbic neurones

1980 • 696 citations

Neuropeptide-containing neurons of the cerebral cortex are also GABAergic.

1984 • 537 citations

Development of a class of selective cholecystokinin type B receptor antagonists having potent anxiolytic activity.

1990 • 501 citations

GABAergic neurons containing CCK‐8‐like and/or VIP‐like immunoreactivities in the rat hippocampus and dentate gyrus

1985 • 325 citations

Cholecystokinin Tetrapeptide Induces Panic-like Attacks in Healthy Volunteers

1989 • 322 citations

Cholecystokinin-Tetrapeptide Induces Panic Attacks in Patients with Panic Disorder

1990 • 289 citations

The role of CCK, caerulein, and CCK antagonists in nociception

1989 • 246 citations

Coexistence of GABA and peptide immunoreactivity in non-pyramidal neurons of the basolateral amygdala

1989 • 218 citations

Behavioural Pharmacology of 5-HT

1990 • 203 citations

An evaluation of the elevated plus-maze test using the novel anxiolytic buspirone

1989 • 192 citations

Benzodiazepines antagonize cholecystokinin-induced activation of rat hippocampal neurones

1984 • 190 citations

Cholecystokinin and anxiety

1990 • 183 citations

Anticonflict effect of the benzodiazepines mediated by a gabaergic mechanism in the amygdala

1982 • 172 citations

Cholecystokinin Modulates the Release of Dopamine from the Anterior and Posterior Nucleus Accumbens by Two Different Mechanisms

1991 • 150 citations

Neuronal Cholecystokinin

1986 • 144 citations

Antinociceptive effects of elevated plus-maze exposure: influence of opiate receptor manipulations

1990 • 138 citations

Classification and function of CCK receptors

1987 • 121 citations

β-Endorphin-induced locomotor stimulation and reinforcement are associated with an increase in dopamine release in the nucleus accumbens

1991 • 114 citations

Rats with anxious or non-anxious type of exploratory behaviour differ in their brain CCK-8 and benzodiazepine receptor characteristics

1990 • 107 citations

Further analysis of the effects of cholecystokinin octapeptides on avoidance behaviour in rats

1984 • 97 citations

Evidence that CCKB receptors mediate the regulation of exploratory behaviour in the rat

1991 • 88 citations

Influence of Dopamine on Limbic Inputs to the Nucleus Accumbens

1988 • 87 citations

Anxiogenic-like action of caerulein, a CCK-8 receptor agonist, in the mouse: influence of acute and subchronic diazepam treatment

1990 • 84 citations

CCK8 effects on motivational and emotional states of rats involve CCKA receptors of the postero-median part of the nucleus accumbens

1989 • 78 citations

Investigation of behavioral and electrophysiological responses induced by selective stimulation of CCKB receptors by using a new highly potent CCK analog, BC 264

1990 • 77 citations

Cholecystokinin and gastrin antagonists

1989 • 74 citations

Long-term diazepam treatment produces changes in cholecystokinin receptor binding in rat brain

1990 • 72 citations

Influences of cholecystokinin and analogues on memory processes

1990 • 70 citations

Pharmacology of a cholecystokinin receptor on 5‐hydroxytryptamine neurones in the dorsal raphe of the rat brain

1991 • 66 citations

Release of cholecystokinin from rat cerebral cortex in vivo: role of GABA and glutamate receptor systems

1987 • 65 citations

Molecular Forms of Cholecystokinin in the Brain and the Relationship to Neuronal Gastrinsa

1985 • 60 citations

Neuropharmacological Profile of Cholecystokinin‐like Peptides

1985 • 59 citations

Behavioral and neurophysiological evidence for a facilatory interaction between co-existing transmitters: cholecystokinin and dopamine

1984 • 59 citations

Neuropeptide modulation of social and exploratory behaviors in laboratory rodents

1981 • 58 citations

Benzodiazepines, putative anxiolytics and animal models of anxiety

1991 • 47 citations

Opposite effects of cholecystokinin octapeptide (CCK-8) and tetrapeptide (CCK-4) after injection into the caudal part of the nucleus accumbens or into its rostral part and the cerebral ventricles

1987 • 46 citations

Evidence for a role for dopamine in the diazepam locomotor stimulating effect

1991 • 42 citations

Hypolocomotion induced by peripheral or central injection of CCK in the mouse is blocked by the CCKA receptor antagonist devazepide but not by the CCKB receptor antagonist L-365,260

1991 • 37 citations

Specificity of nucleus accumbens to activities related to cholecystokinins in rats

1985 • 36 citations

The behavioral effects of CCK8 injected into the medial nucleus accumbens are dependent on the motivational state of the rat

1989 • 25 citations

Modulation of Mesolimbic Dopaminergic Behaviors by Cholecystokinin

1988 • 23 citations

CCK-8 modulates D2 receptor agonist-induced hypermotility in the nucleus accumbens

1991 • 12 citations

EVIDENCE THAT THE ANXIOLYTIC-LIKE EFFECTS OF THE CCK ANTAGONISTS DEVAZEPIDE AND L-365,260 IN THE ELEVATED PLUS-MAZE PARADIGM IN RATS ARE MEDIATED BY CCK RECEPTORS

1990 • 12 citations