Elastin: molecular description and function

Statistical mechanics of chain molecules

1969 • 6,455 citations

Deterministic chaos: An introduction

1984 • 1,529 citations

Hemizygosity at the elastin locus in a developmental disorder, Williams syndrome

1993 • 1,135 citations

The structure and chemical characterization of elastic fibers as reveled by elastase and by electron microscopy

1952 • 525 citations

The chemistry of connective tissues. 2. Soluble proteins derived from partial hydrolysis of elastin

1955 • 477 citations

The elastin gene is disrupted by a translocation associated with supravalvular aortic stenosis

1993 • 419 citations

Entropic elastic processes in protein mechanisms. I. Elastic structure due to an inverse temperature transition and elasticity due to internal chain dynamics

1988 • 397 citations

Val-Gly-Val-Ala-Pro-Gly, a repeating peptide in elastin, is chemotactic for fibroblasts and monocytes.

1984 • 388 citations

Alternative splicing of human elastin mRNA indicated by sequence analysis of cloned genomic and complementary DNA.

1987 • 316 citations

The elastic properties of elastin

1974 • 314 citations

The Elastin Receptor: A Galactoside-Binding Protein

1988 • 303 citations

Amplitude Instability and Ergodic Behavior for Conservative Nonlinear Oscillator Systems

1969 • 297 citations

Elastin point mutations cause an obstructive vascular disease, supravalvular aortic stenosis

1997 • 275 citations

Isolation and Amino Acid Sequences of Tropoelastin Peptides

1973 • 269 citations

Purification and partial characterization of a soluble elastin-like protein from copper-deficient procine aorta

1969 • 238 citations

Total synthesis and expression in Escherichia coli of a gene encoding human tropoelastin

1995 • 190 citations

67-kD elastin-binding protein is a protective "companion" of extracellular insoluble elastin and intracellular tropoelastin.

1994 • 172 citations

Identification of an Elastin Cross-linking Domain That Joins Three Peptide Chains

1995 • 167 citations

Elastin: genomic structure and point mutations in patients with supravalvular aortic stenosis

1997 • 155 citations

Primary structures of bovine elastin a, b, and c deduced from the sequences of cDNA clones.

1987 • 153 citations

Sequence Variation of Bovine Elastin mRNA Due to Alternative Splicing

1987 • 146 citations

Characterization of The Complete Human Elastin Gene

1989 • 144 citations

Transforming growth factor-beta up-regulates elastin gene expression in human skin fibroblasts. Evidence for post-transcriptional modulation.

1992 • 136 citations

Supravalvular aortic stenosis. Clinical and pathologic observations in six patients.

1985 • 123 citations

Functional domains on elastin and microfibril-associated glycoprotein involved in elastic fibre assembly

1996 • 122 citations

Repeating structure of chick tropoelastin revealed by complementary DNA cloning

1987 • 117 citations

Bovine Elastin and κ-Elastin Secondary Structure Determination by Optical Spectroscopies

1995 • 113 citations

Coacervation of Solubilized Elastin effects a Notable Conformational Change

1969 • 113 citations

Human elastin gene: new evidence for localization to the long arm of chromosome 7.

1991 • 99 citations

Synthetic fragments and analogues of elastin. II. Conformational studies

1990 • 88 citations

Heterogeneity of rat tropoelastin mRNA revealed by cDNA cloning

1990 • 74 citations

Studies on the Conformation and Interactions of Elastin

1974 • 68 citations

Scanning Electron Microscope Observatlons on Elastin

1972 • 67 citations

Congenital cutis laxa and lysyl oxidase deficiency

1997 • 63 citations

Elastin and elastases

1989 • 61 citations

Molecular Pathology of the Elastic Fibers

1994 • 60 citations

Evidence for Order in the Structure of α-Elastin

1968 • 58 citations

Synthesis and Structural Studies of a Pentapeptide Sequence of Elastin. Poly (Val-Gly-Gly-Leu-Gly)

1992 • 57 citations

Tissue-specific and developmentally regulated expression of human elastin promoter activity in transgenic mice.

1994 • 53 citations

Effect of Age and IGF-I Administration on Elastin Gene Expression in Rat Aorta

1990 • 52 citations

Biosynthesis of the desmosine and isodesmosine cross-bridges in elastin.

1964 • 52 citations

Structure‐activity relationships for some elastin‐derived peptide chemoattractants

1997 • 52 citations

Chemotaxis of fibroblasts toward nonapeptide of elastin

1988 • 52 citations

Migration of monocytes in the presence of elastolytic fragments of elastin and in synthetic derivates Structure‐activity relationships

1994 • 49 citations

Molecular dynamics study of the conformational behavior of a representative elastin building block: Boc‐Gly‐Val‐Gly‐Gly‐Leu‐Ome

1992 • 48 citations

Alternative Splicing of Rat Tropoelastin mRNA is Tissue-Specific and Developmentally Regulated

1991 • 47 citations

Isolation and characterization of insoluble and kappa elastins

1985 • 46 citations

An Aggregating Elastin-Like Pentapeptide

1993 • 44 citations

Predictions of the secondary structure and antigenicity of human and bovine tropoelastins

1992 • 39 citations

Arterial mesenchyme and arteriosclerosis. Studies on the conformation and interaction of elastin.

1974 • 38 citations

Elastin in Blood Vessels

2007 • 38 citations

Elastoderma — Disease of Elastin Accumulation within the Skin

1985 • 37 citations

Polypeptide models of elastin: CD and NMR studies on synthetic poly(X‐Gly‐Gly)

1991 • 36 citations

Concentration-dependent conformational transition of alpha-elastin in aqueous solution.

1978 • 29 citations

Use of an Intron Length Polymorphism to Localize the Tropoelastin Gene to Mouse Chromosome 5 in a Region of Linkage Conservation with Human Chromosome 7

1994 • 29 citations

Comparison of Soluble and Native Elastin Conformations by Far-ultraviolet Circular Dichroism

1970 • 29 citations

Spectroscopic studies on elastin-like synthetic polypeptides

1990 • 28 citations

Regulation of Elastin Synthesis in Pathological States

2007 • 25 citations

Conformational Modeling of Elastin Tetrapeptide Boc-Gly-Leu-Gly-Gly-NMe by Molecular Dynamics Simulations with Improvements to the Thermalization Procedure

1995 • 25 citations

Solid-state studies on synthetic fragments and analogues of elastin

1993 • 24 citations

Molecular Pathology of the Elastic Fibers.

1994 • 20 citations

Structure of the Elastin Gene

2007 • 19 citations

Phase transitions and chain dynamics, in the solid state, of a pentapeptide sequence of elastins

1992 • 19 citations

Conformational changes induced in α-elastin by cholesterol, taurocholate and unsaturated fatty acids

1980 • 19 citations

Conformational non-linear dynamical behavior of the peptide Boc-Gly-Leu-Gly-Gly-NMe

1997 • 15 citations

SOLUBLE FRAGMENTS OF ELASTIN. CIRCULAR DICHROISM STUDIES

1973 • 14 citations

Human α-elastins: lipid-induced conformational changes

1982 • 12 citations

Improvements to the molecular dynamics simulated annealing procedures: conformational search of the elastin tetrapeptide Boc-Gly-Leu-Gly-Gly-NMe

1994 • 11 citations

Extensive alternate exon usage at the 5′ end of the sheep tropoelastin gene

1995 • 9 citations

Elastin: molecular and supramolecular structure.

1981 • 8 citations

Classical and fractal description of elastin structure

1991 • 7 citations