Re-evaluation of the functional anatomy of the basal ganglia in normal and Parkinsonian states

The functional anatomy of basal ganglia disorders

1989 • 5,166 citations

Primate models of movement disorders of basal ganglia origin

1990 • 3,722 citations

Functional anatomy of the basal ganglia. II. The place of subthalamic nucleus and external pallidium in basal ganglia circuitry

1995 • 1,339 citations

Cytochrome oxidase: an endogenous metabolic marker for neuronal activity

1989 • 1,231 citations

Nonlinear relationship between impulse flow and dopamine released by rat midbrain dopaminergic neurons as studied by in vivo electrochemistry

1988 • 663 citations

Abnormal spontaneous activity of globus pallidus neurons in monkeys with MPTP-induced parkinsonism

1991 • 641 citations

Regulation of γ‐Aminobutyric Acid Synthesis in the Brain

1993 • 596 citations

Metabolic Mapping of Functional Activity in the Hypothalamo-Neurohypophysial System of the Rat

1979 • 464 citations

Neural mechanisms underlying parkinsonian symptoms based upon regional uptake of 2-deoxyglucose in monkeys exposed to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1989 • 455 citations

Altered Tonic Activity of Neurons in the Globus Pallidus and Subthalamic Nucleus in the Primate MPTP Model of Parkinsonism

1987 • 420 citations

Excitatory influence of rat subthalamic nucleus to substantia nigra pars reticulata and the pallidal complex: electrophysiological data

1990 • 343 citations

Increased subthalamic neuronal activity after nigral dopaminergic lesion independent of disinhibition via the globus pallidus

1996 • 340 citations

Efferent connections of the centromedian and parafascicular thalamic nuclei in the squirrel monkey: A PHA‐L study of subcortical projections

1992 • 339 citations

Neurons of the subthalamic nucleus in primates display glutamate but not GABA immunoreactivity

1988 • 326 citations

Basal ganglia intrinsic circuits and their role in behavior

1993 • 324 citations

Afferent connections of the subthalamic nucleus: a combined retrograde and anterograde horseradish peroxidase study in the rat

1990 • 294 citations

Intracellular study of rat globus pallidus neurons: membrane properties and responses to neostriatal, subthalamic and nigral stimulation

1991 • 285 citations

Different distributions of GAD₆₅ and GAD₆₇ mRNAS suggest that the two glutamate decarboxylases play distinctive functional roles

1993 • 285 citations

Subthalamotomy in parkinsonian monkeys Behavioural and biochemical analysis

1996 • 258 citations

Comparative distribution of mRNAs for glutamic acid decatrboxylase, tyrosine hydroxylase, and tachykinins in the basal ganglia: An in situ hybridization study in the rodent brain

1987 • 232 citations

Detection of the nicotinic acetylcholine receptor alpha-subunit mRNA by in situ hybridization at neuromuscular junctions of 15-day-old chick striated muscles.

1988 • 217 citations

Anatomy and Physiology of the Subthalamic Nucleus: A Driving Force of the Basal Ganglia

1987 • 206 citations

Unilateral lesion of the nigrostriatal pathway decreases the firing rate and alters the firing pattern of globus pallidus neurons in the rat

1988 • 183 citations

Effects of interruption of the nigrostriatal pathway and of dopaminergic agents on the spontaneous activity of globus pallidus neurons in the awake monkey

1979 • 172 citations

Differential synaptic innervation of neurons in the internal and external segments of the globus pallidus by the GABA‐ and glutamate‐containing terminals in the squirrel monkey

1995 • 157 citations

Dynamic utilization of GABA in substantia nigra: regulation by dopamine and GABA in the striatum, and its clinical and behavioral implications

1981 • 154 citations

Tissue levels and in vivo release of tachykinins and GABA in striatum and substantia nigra of rat brain after unilateral striatal dopamine denervation

1989 • 139 citations

Excitotoxic acid lesions of the primate subthalamic nucleus result in reduced pallidal neuronal activity during active holding

1992 • 128 citations

Pathophysiology of parkinsonian motor abnormalities.

1993 • 124 citations

Convergence of subthalamic and striatal efferents at pallidal level in primates: an anterograde double-labeling study with biocytin and PHA-L

1992 • 117 citations

Parallel increases in striatal glutamic acid decarboxylase activity and mRNA levels in rats with lesions of the nigrostriatal pathway

1990 • 111 citations

Concomitant increase of somatostatin, neuropeptide y and glutamate decar☐ylase in the frontal cortex of rats with decreased seizure threshold

1988 • 109 citations

Dopaminergic mechanisms in subthalamic nucleus of rat: analysis using horseradish peroxidase and microiontophoresis

1985 • 109 citations

Effects of nigrostriatal lesions on the levels of messenger RNAs encoding two isoforms of glutamate decarboxylase in the globus pallidus and entopeduncular nucleus of the rat

1992 • 103 citations

Metabolic activity of the basal ganglia in parkinsonian syndromes in human and non-human primates: A cytochrome oxidase histochemistry study

1996 • 102 citations

Neuronal expression of nuclear and mitochondrial genes for cytochrome oxidase (CO) subunits analyzed by in situ hybridization: comparison with CO activity and protein

1991 • 99 citations

Electrophysiological study of the excitatory parafascicular projection to the subthalamic nucleus and evidence for ipsi- and contralateral controls

1995 • 98 citations

Coordination of ATP production and consumption in brain: Parallel regulation of cytochrome oxidase and Na+, K+-ATPase

1992 • 95 citations

Evidence that the parafascicular projection to the subthalamic nucleus is glutamatergic

1993 • 93 citations

Synaptic innervation of neurons in the internal pallidal segment by the subthalamic nucleus and the external pallidum in monkeys

1994 • 93 citations

Consequence of nigrostriatal denervation and L-dopa therapy on the expression of glutamic acid decarboxylase messenger RNA in the pallidum

1996 • 91 citations

Increased glutamate decarboxylase mRNA levels in the striatum and pallidum of MPTP-treated primates

1994 • 82 citations

Burst stimulation of the medial forebrain bundle selectively increases Fos-like immunoreactivity in the limbic forebrain of the rat

1996 • 82 citations

Excitatory effect of iontophoretically applied dopamine on identified neurons of the rat subthalamic nucleus

1986 • 75 citations

The globus pallidus receives a projection from the parafascicular nucleus in the rat

1991 • 67 citations

Increased glutamic acid decarboxylase (GAD) mRNA and GAD activity in cerebellar Purkinje cells following lesion-induced increases in cell firing

1990 • 67 citations

Differential patterns of arborization of striatal and subthalamic fibers in the two pallidal segments in primates

1992 • 67 citations

Consequences of nigrostriatal denervation on the gamma-aminobutyric acidic neurons of substantia nigra pars reticulata and superior colliculus in parkinsonian syndromes

1996 • 66 citations

Characterization of dopamine receptor binding sites in the subthalamic nucleus

1994 • 62 citations

Effects of Nigrostriatal Denervation and L‐Dopa Therapy on the GABAergic Neurons of the Striatum in MPTP‐treated Monkeys and Parkinson's Disease: An In Situ Hybridization Study of GAD₆₇ mRNA

1995 • 59 citations

6-Hydroxydopamine lesions of the nigrostriatal pathway alter the expression of glutamate decarboxylase messenger RNA in rat globus pallidus projection neurons

1992 • 53 citations

Excitotoxic lateral pallidotomy does not relieve L-DOPA-induced dyskinesia in MPTP parkinsonian monkeys

1994 • 48 citations

Cerebral metabolism of Parkinsonian primates 21 days after MPTP

1988 • 40 citations

Delayed reduction in GABA and GAD immunoreactivity of neurons in the adult monkey dorsal lateral geniculate nucleus following monocular deprivation or enucleation

1991 • 38 citations

Current concepts in Parkinson's disease research

1995 • 31 citations

Changes in the activity of GAD in the basal ganglia of the rat after striatal dopaminergic denervation

1987 • 30 citations

Effect of subthalamic nucleus lesion on mitochondrial enzyme activity in rat basal ganglia

1995 • 26 citations

Glutamic acid decarboxylase mRNA expression in medial and lateral pallidal neurons in the MPTP-treated monkey and patients with Parkinson's disease.

1996 • 23 citations

Rapid increases in cerebellar Purkinje cell glutamic acid decar☐ylase (GAD67) mRNA after lesion-induced increases in cell firing

1993 • 17 citations

GABA levels and GAD immunoreactivity in the deep cerebellar nuclei of rats with altered olivo-cerebellar function

1992 • 15 citations

Metabolic activation of specific postsynaptic elements in superior cervical ganglion by antidromic stimulation of external carotid nerve

1985 • 15 citations

In situ hybridization of GAD mRNA in monkey and human brain: quantification at both regional and cellular levels

1993 • 12 citations

Chapter 6 Striatal and subthalamic afferents to the primate pallidum: interactions between two opposite chemospecific neuronal systems

1993 • 11 citations