Enhanced efficacy of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanine in combination with gamma interferon against herpes simplex virus type 2 in mice

A Method for Testing for Synergy with Any Number of Agents

1978 • 727 citations

9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine: a selective inhibitor of herpes group virus replication.

1983 • 384 citations

Anti-herpesvirus activity of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanine

1983 • 262 citations

Unique spectrum of activity of 9-[(1,3-dihydroxy-2-propoxy)methyl]-guanine against herpesviruses in vitro and its mode of action against herpes simplex virus type 1.

1983 • 247 citations

A new nucleoside analog, 9-[[2-hydroxy-1-(hydroxymethyl)ethoxyl]methyl]guanine, highly active in vitro against herpes simplex virus types 1 and 2

1982 • 245 citations

Activation of human monocyte cytotoxicity by natural and recombinant immune interferon.

1983 • 220 citations

Prevention of Reactivated Herpes Simplex Infection by Human Leukocyte Interferon after Operation on the Trigeminal Root

1979 • 206 citations

Activation by thymidine kinase and potent antiherpetic activity of 2′-nor-2′-deoxyguanosine (2′NDG)

1982 • 188 citations

Treatment of Cytomegaloviral Pneumonia with High-Dose Acyclovir and Human Leukocyte Interferon

1983 • 78 citations

Inhibition of human herpesviruses by combination of acyclovir and human leukocyte interferon

1981 • 70 citations

Combined Antiviral Effect of Interferon and Acyclovir on Herpes Simplex Virus Types 1 and 2

1981 • 57 citations

Relative activities of acyclovir and BW759 against Aujeszky's disease and equine rhinopneumonitis viruses

1983 • 55 citations

Combination Therapy for Dendritic Keratitis With Acyclovir and -Interferon

1983 • 49 citations

Recombinant gamma interferon enhances natural killer cell activity similar to natural gama interferon

1983 • 41 citations

Enhanced efficacy of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanine in combination with alpha-interferon against herpes simplex virus type 2 in mice

1984 • 36 citations

Effect of Treatment with Exogenous Interferon, Polyriboinosinic-Polyribocytidylic Acid, or Polyriboinosinic-Polyribocytidylic Acid-Poly-L-Lysine Complex on Herpesvirus hominis Infections in Mice

1978 • 28 citations

Combined interaction of antiherpes substances and interferon ? on the multiplication of herpes simplex virus

1982 • 27 citations

Potent synergistic inhibition of herpes simplex virus-2 by 9-[(1, 3-dihydroxy-2-propoxy) methyl]guanine in combination with recombinant interferons

1984 • 26 citations

Antiviral Activities of Cloned Human Leukocyte Interferons against Herpes Simplex Virus Type 2 Infections of Mice

1983 • 24 citations

Efficacy of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanine against primary and recrudescent genital herpes simplex virus type 2 infections in guinea pigs

1983 • 21 citations

Enhanced efficacy of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanine in combination with beta-interferon against herpes simplex virus type 2 in mice

1984 • 20 citations

Interferon in acute viral infections

1983 • 15 citations

Evaluation of interferon and interferon inducers as antiviral agents: Animal studies

1981 • 14 citations

Interferon in ocular viral diseases.

1982 • 11 citations

Treatment of murine cytomegalovirus pneumonia with acyclovir and interferon.

1983 • 10 citations