Interleukin-1α in blood has direct access to cortical brain cells

Graphical Evaluation of Blood-to-Brain Transfer Constants from Multiple-Time Uptake Data

1983 • 3,439 citations

Defective Glucose Transport across the Blood-Brain Barrier as a Cause of Persistent Hypoglycorrhachia, Seizures, and Developmental Delay

1991 • 747 citations

Murine tumor necrosis factor alpha is transported from blood to brain in the mouse

1993 • 561 citations

Transport of α-Aminoisobutyric Acid across Brain Capillary and Cellular Membranes

1983 • 510 citations

Capillary Depletion Method for Quantification of Blood–Brain Barrier Transport of Circulating Peptides and Plasma Proteins

1990 • 454 citations

Human interleukin (IL) 1 alpha, murine IL-1 alpha and murine IL-1 beta are transported from blood to brain in the mouse by a shared saturable mechanism.

1991 • 449 citations

The cell surface receptors for interleukin-1α and interleukin-1β are identical

1986 • 422 citations

Immunoregulators in the nervous system

1991 • 380 citations

Bidirectional transport of interleukin-1 alpha across the blood-brain barrier

1989 • 323 citations

Frontiers in Neuroendocrinology, 1973.

1973 • 302 citations

Interleukin 1 receptor antagonist is a member of the interleukin 1 gene family: evolution of a cytokine control mechanism.

1991 • 243 citations

Blood to brain transport of interleukin links the immune and central nervous systems

1991 • 174 citations

Central action of recombinant interleukin-1 to inhibit acid secretion in rats

1990 • 88 citations

The effects of continuous administration of murine interleukin-1α in the rat

1988 • 85 citations

Recycling kinetics and transcytosis of transferrin in primary cultures of bovine brain microvessel endothelial cells

1991 • 82 citations

The interleukins-1α, -1β, and -2 do not acutely disrupt the murine blood - brain barrier

1992 • 59 citations

Effects of interleukin-1 infused into brain are antagonized by α-MSH in a dose-dependent manner

1991 • 54 citations

Spinal transection reduces both spinal antinociception and CNS concentration of systemically administered morphine in rats

1991 • 44 citations