Evidence for the involvement of brain GABA and serotonin systems in the anticonflict effects of chlordiazepoxide in rats

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p-Chlorophenylalanine: a specific depletor of brain serotonin.

1966 • 1,754 citations

Receptors for the Age of Anxiety: Pharmacology of the Benzodiazepines

1980 • 866 citations

The effects of meprobamate, barbiturates, d-amphetamine and promazine on experimentally induced conflict in the rat

1960 • 785 citations

Resolution of two biochemically and pharmacologically distinct benzodiazepine receptors

1979 • 408 citations

Drug Effects on Fear and Frustration: Possible Limbic Site of Action of Minor Tranquilizers

1977 • 372 citations

Benzodiazepines: Potentiation of a GABA inhibitory response in the dorsal raphe nucleus

1978 • 280 citations

Increase of ?antianxiety? activity and tolerance of behavioral depression during chronic administration of oxazepam

1968 • 232 citations

Tryptaminergic mechanisms in punished and nonpunished behavior.

1970 • 182 citations

GABA-picrotoxin interaction in the mammalian central nervous system

1969 • 164 citations

The effects of 5-HTP on para-chlorophenylalanine (p-CPA) attenuation of “conflict” behavior

1970 • 163 citations

Withdrawal Reaction From Long-term, Low-dosage Administration of Diazepam

1980 • 158 citations

Studies on the role of ACTH and of 5-HT in anxiety, using an animal model

1978 • 154 citations

Effects of benzodiazepines on central serotonergic mechanisms.

1975 • 143 citations

The effects of benzodiazepines and serotonergic manipulations on punished responding

1979 • 136 citations

Anti-anxiety action op diazepam after intraamygdaloid application in the rat

1979 • 130 citations

The effects of naloxone and picrotoxin on the sedative and anticonflict effects of benzodiazepines

1978 • 124 citations

Distribution and metabolism of muscimol in the brain and other tissues of the rat

1979 • 115 citations

A water lick conflict paradigm using drug experienced rats

1981 • 103 citations

Comparison of anti-conflict drug effects in three experimental animal models of anxiety

1981 • 101 citations

The effects of chlordiazepoxide HCl administration upon punishment and conditioned suppression in the rat

1980 • 80 citations

Synaptic pharmacology of barbiturates and benzodiazepines

1977 • 69 citations

Mechanisms of action of benzodiazepines

1990 • 55 citations

Anorexic effects of ethanolamine-O-sulfate and muscimol in the rat: Evidence that GABA inhibits ingestive behavior

1980 • 54 citations

Chlordiazepoxide and GABA injected into raphé dorsalis release the conditioned behavioural suppression induced in rats by a conflict procedure without nociceptive component

1980 • 53 citations

γ-Aminobutyric acid metabolism in rat brain following chronic oral administration of ethanolamine O-sulphate

1980 • 51 citations

Effect of diazepam on cerebral 5-hydroxytryptamine synthesis

1979 • 47 citations

Rotational behaviour elicited by 5-HT in the rat: evidence for an inhibitory role of 5-HT in the substantia nigra and corpus striatum

1980 • 47 citations

Electrophysiological actions of benzodiazepines.

1980 • 31 citations

Benzodiazepines: a tool to explore the biochemical and neurophysiological basis of anxiety.

1980 • 24 citations

Effects of chronic chlordiazepoxide treatment on novel and familiar food preference in rats

1981 • 18 citations

Evidence of a role for GABA in benzodiazepine effects on food preference in rats

1981 • 18 citations