Anti-(transforming growth factor ?) antibodies with predefined specificity inhibit metastasis of highly tumorigenic human xenotransplants in nu/nu mice

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

Transforming growth factor beta

2011 • 1,990 citations

[1] Preparation of monoclonal antibodies: Strategies and procedures

1981 • 1,787 citations

Autocrine growth factors and cancer

1985 • 1,462 citations

An enzyme-release assay for natural cytotoxicity

1983 • 1,063 citations

Characteristics of human large granular lymphocytes and relationship to natural killer and K cells

1981 • 1,008 citations

Synthesis of messenger RNAs for transforming growth factors alpha and beta and the epidermal growth factor receptor by human tumors.

1987 • 895 citations

Transforming Growth Factor‐β

1990 • 696 citations

Two forms of transforming growth factor-β distinguished by multipotential haematopoietic progenitor cells

1987 • 407 citations

Anti-transforming growth factor (TGF)-beta antibodies inhibit breast cancer cell tumorigenicity and increase mouse spleen natural killer cell activity. Implications for a possible role of tumor cell/host TGF-beta interactions in human breast cancer progression.

1993 • 356 citations

An unusual feature revealed by the crystal structure at 2.2 Å resolution of human transforming growth fact or-β2

1992 • 337 citations

Resistance to inhibition of cell growth by transforming growth factor-beta and its role in oncogenesis.

1993 • 239 citations

Molecular and functional analysis of human natural killer cell-associated neural cell adhesion molecule (N-CAM/CD56).

1991 • 194 citations

Growth Dominance of the Metastatic Cancer Cell: Cellular and Molecular Aspects

1990 • 179 citations

Cytolytic and cytostatic activity on tumor cells of circulating human monocytes

1979 • 177 citations

The autocrine production of transforming growth factor-beta 1 during lymphocyte activation. A study with a monoclonal antibody-based ELISA.

1990 • 169 citations

Elevated levels of transforming growth factor beta messenger RNA and its polypeptide in human hepatocellular carcinoma.

1991 • 150 citations

Loss of growth factor dependence and conversion of transforming growth factor-beta 1 inhibition to stimulation in metastatic H-ras-transformed murine fibroblasts.

1988 • 113 citations

Transforming growth factor beta and fibroblast growth factor as promoters of tumor progression to malignancy.

1993 • 82 citations

Immunodetection and modulation of cellular growth with antibodies against native transforming growth factor-beta 1.

1987 • 68 citations

Immunocytochemically Detectable TGF-β Associated with Malignancy in Thyroid Epithelial Neoplasia

1990 • 63 citations

Aberrant TGF-β Production and Regulation in Metastatic Malignancy

1990 • 59 citations

Cytotoxicity to tumor cells of monocytes from normal individuals and cancer patients

1980 • 45 citations

Transforming growth factor beta and the cell surface in tumor progression

1993 • 41 citations

Growth of human colonic adenocarcinoma and development of serum CEA in athymic mice. I: strict correlation of tumour size and mass with serum CEA concentration during logarithmic growth

1982 • 29 citations

Growth stimulation, altered regulation of epidermal growth factor receptors, and autocrine transformation of spontaneously transformed normal rat kidney cells by transforming growth factor beta.

1989 • 25 citations

Role of Transforming Growth Factorβin Colorectal Cancer

1993 • 25 citations

Differential expression of transforming growth factor-beta 1 gene in 3LL metastatic variants.

1991 • 19 citations

Activation of Human Monocyte and Natural Killer Cell‐Mediated Tumour Cell Killing by Two Dialysable Thymic Factors

1986 • 17 citations

Identification of a mannose-acetate-specific 87-kDa receptor responsible for human NK and LAK activity

1994 • 14 citations

Induction of anchorage-independent growth by epidermal growth factor and altered sensitivity to type beta transforming growth factor in partially transformed rat kidney cells.

1986 • 12 citations

Activation of human monocyte/macrophage cytotoxicity by IL-2/IFNγ is linked to increased expression of an antitumor receptor with specificity for acetylated mannose

1993 • 11 citations

Lack of expression of a 31/33kD surface protein on human colon carcinoma cells is a marker for metastasizing potential.

1994 • 2 citations

Autoimmune expression of a cytoplasmic protein p60 in mice bearing metastasizing SV40‐transformed tumors

1988 • 2 citations