Cytogenetic damage induced by folate deficiency in mice is enhanced by caffeine.

Quantitative comparison of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey, and man.

1966 • 1,363 citations

The induction of micronuclei as a measure of genotoxicity

1983 • 761 citations

Constitutive Fragile Sites and Cancer

1984 • 693 citations

Diet and health: Implications for reducing chronic disease risk

1990 • 646 citations

Multivitamin/folic acid supplementation in early pregnancy reduces the prevalence of neural tube defects

1989 • 629 citations

Radioprotectors and anticarcinogens

1983 • 613 citations

Heritable fragile sites on human chromosomes I. Factors affecting expression in lymphocyte culture.

1979 • 488 citations

An application of Acridine Orange fluorescent staining to the micronucleus test

1983 • 407 citations

Principles and methods of toxicology

1989 • 375 citations

Caffeine-Induced Uncoupling of Mitosis from the Completion of DNA Replication in Mammalian Cells

1986 • 328 citations

THE MUTAGENIC ACTIVITY OF 61 AGENTS AS DETERMINED BY THE MICRONUCLEUS, SALMONELLA, AND SPERM ABNORMALITY ASSAYS

1979 • 283 citations

Clastogen‐induced micronuclei in peripheral blood erythrocytes: The basis of an improved micronucleus test

1980 • 245 citations

Improvement in cervical dysplasia associated with folic acid therapy in users of oral contraceptives

1982 • 215 citations

Ten model mutagens evaluated by the micronucleus test

1976 • 202 citations

Proposed Mechanism of Inheritance and Expression of the Human Fragile-X Syndrome of Mental Retardation

1987 • 190 citations

Subnormal Serum Folate and Macrocytosis Associated with Anticonvulsant Drug Therapy

1964 • 177 citations

Towards an improved micronucleus test Studies on 3 model agents, mitomycin C, cyclophosphamide and dimethylbenzanthracene

1980 • 172 citations

Caffeine and chromosomes

1978 • 165 citations

Analysis of Folate Data from the Second National Health and Nutrition Examination Survey (NHANES II)

1985 • 149 citations

Cytogenetic Observations in Vitamin B12 and Folate Deficiency

1966 • 124 citations

Association of Marginal Folate Depletion With Increased Human Chromosomal Damage In Vivo: Demonstration by Analysis of Micronucleated Erythrocytes

1988 • 121 citations

Molecular mechanisms of DNA repair inhibition by caffeine.

1990 • 119 citations

Physiological Disposition of Caffeine

1975 • 117 citations

Mutagenesis and deoxyribonucleotide pool imbalance

1988 • 105 citations

Cytogenetic and Cytochemical Studies on Marrow Cells in B12 and Folate Deficiency

1966 • 99 citations

Factors affecting the induction of micronuclei at low doses of X-rays, MMS and dimethylnitrosamine in mouse erythroblasts

1978 • 97 citations

Studies on micronuclei time response and on the effects of multiple treatments of mutagens on induction of micronuclei

1981 • 96 citations

Methylxanthines: Toxicity to humans. 2. Caffeine

1988 • 92 citations

Goodman and Gilman's The Pharmacological Basis of Therapeutics

1981 • 91 citations

Increased chromosome fragility as a consequence of blood folate levels, smoking status, and coffee consumption

1989 • 80 citations

Assessment of cytogenetic damage by quantitation of micronuclei in human peripheral blood erythrocytes.

1986 • 72 citations

Fragile Sites in Chromosomes: Possible Model for the Study of Spontaneous Chromosome Breakage

1983 • 70 citations

Fragile sites, cancer chromosome breakpoints, and oncogenes all cluster in light G bands

1988 • 69 citations

A simple fluorescent staining procedure for micronuclei and RNA in erythrocytes using Hoechst 33258 and pyronin Y

1983 • 64 citations

No statistical association between common fragile sites and nonrandom chromosome breakpoints in cancer cells

1988 • 59 citations

Folacin and iron status and hematological findings in predominately black elderly persons from urban low-income households

1979 • 58 citations

Fragile sites: Overview, occurrence in acute nonlymphocytic leukemia and effects of caffeine on expression

1986 • 51 citations

Micronucleated erythrocytes as an index of cytogenetic damage in humans: demographic and dietary factors associated with micronucleated erythrocytes in splenectomized subjects.

1990 • 47 citations

Effects of caffeine on purine metabolism and ultraviolet light-induced lethality in cultured mammalian cells.

1979 • 28 citations

Effects of folate deficiency on the metastatic potential of murine melanoma cells.

1988 • 26 citations

The effect of caffeine in the in vivo SCE and micronucleus mutagenicity tests

1986 • 20 citations

Non-clastogenicity in mouse bone marrow of fructose/lysine and other sugar/amino acid browning products with in vitro genotoxicity

1989 • 17 citations

Sixth International Caffeine Workshop, Hong Kong, 7–10 August 1989

1990 • 3 citations