Levels of angiotensin and molecular biology of the tissue renin angiotensin systems

Isolation of a cDNA encoding the vascular type-1 angiotensin II receptor

1991 • 1,247 citations

Identification of angiotensin II receptor subtypes

1989 • 825 citations

Cloning and expression of a complementary DNA encoding a bovine adrenal angiotensin II type-1 receptor

1991 • 808 citations

Functions of Angiotensin in the Central Nervous System

1987 • 726 citations

Increased rat cardiac angiotensin converting enzyme activity and mRNA expression in pressure overload left ventricular hypertrophy. Effects on coronary resistance, contractility, and relaxation.

1990 • 607 citations

Angiotensinogen gene is expressed and differentially regulated in multiple tissues of the rat.

1986 • 484 citations

Renin-angiotensin system involvement in pressure-overload cardiac hypertrophy in rats

1990 • 409 citations

The mas oncogene encodes an angiotensin receptor

1988 • 390 citations

Converting Enzyme Inhibition Specifically Prevents the Development and Induces Regression of Cardiac Hypertrophy in Rats

1989 • 344 citations

Astrocytes Synthesize Angiotensinogen in Brain

1988 • 321 citations

Angiotensin II type-1 receptor subtype cDNAs: Differential tissue expression and hormonal regulation

1992 • 317 citations

Mapping of angiotensin II receptor subtype heterogeneity in rat brain

1992 • 308 citations

Cloning and expression of a novel angiotensin II receptor subtype.

1992 • 270 citations

Discovery of a distinct binding site for angiotensin II (3–8), a putative angiotensin IV receptor

1992 • 265 citations

A Comparative Study of the Distributions of Renin and Angiotensinogen Messenger Ribonucleic Acids in Rat and Mouse Tissues*

1987 • 260 citations

Tissue distribution of rat angiotensinogen mRNA and structural analysis of its heterogeneity.

1986 • 256 citations

Analysis by immunocytochemistry and in situ hybridization of renin and its mRNA in kidney, testis, adrenal, and pituitary of the rat.

1986 • 250 citations

Angiotensin II: Rapid Localization in Nuclei of Smooth and Cardiac Muscle

1971 • 241 citations

Isolation and characterization of renin-like enzymes from mouse submaxillary glands

1972 • 215 citations

Prorenin in High Concentrations in Human Ovarian Follicular Fluid

1986 • 209 citations

Angiotensin II induces c-fos expression in smooth muscle via transcriptional control.

1989 • 206 citations

Localization of angiotensin converting enzyme in rat heart.

1991 • 205 citations

Angiotensin II increases spontaneous contractile frequency and stimulates calcium current in cultured neonatal rat heart myocytes: insights into the underlying biochemical mechanisms.

1988 • 199 citations

Molecular mechanisms of vascular renin-angiotensin system in myointimal hyperplasia.

1991 • 195 citations

Endothelial renin-angiotensin pathway: evidence for intracellular synthesis and secretion of angiotensins.

1987 • 190 citations

Identification of renin and angiotensinogen messenger RNA sequences in mouse and rat brains.

1986 • 190 citations

[Sar1]angiotensin II receptor-mediated stimulation of protein synthesis in chick heart cells

1990 • 188 citations

Evidence for an endogenous brain renin-angiotensin system.

1979 • 174 citations

Sodium regulation of angiotensinogen mRNA expression in rat kidney cortex and medulla.

1986 • 160 citations

Molecular biology of the renin-angiotensin system

1988 • 156 citations

Localization of preangiotensinogen messenger RNA sequences in the rat brain.

1986 • 156 citations

Angiotensin II Receptors in Normal and Failing Human Hearts*

1989 • 153 citations

Cardiac angiotensinogen and its local activation in the isolated perfused beating heart.

1990 • 152 citations

Cellular Localization of Angiotensinogen Gene Expression in Brown Adipose Tissue and Mesentery: Quantification of Messenger Ribonucleic Acid Abundance Using Hybridization in Situ*

1987 • 147 citations

Identification and characterization of functional angiotensin II receptors on cultured heart myocytes.

1986 • 145 citations

Induction of the proto-oncogene c-jun by angiotensin II.

1990 • 143 citations

Tissue and gene specificity of mouse renin expression.

1984 • 138 citations

Localization of angiotensinogen messenger RNA in rat aorta.

1988 • 136 citations

Quantitative Autoradiography Reveals Different Angiotensin II Receptor Subtypes in Selected Rat Brain Nuclei

1991 • 134 citations

Extra-renal transcription of the renin genes in multiple tissues of mice and rats.

1989 • 127 citations

Structure of Testicular Angiotensin-converting Enzyme

1989 • 126 citations

Recruitment of renin gene-expressing cells in adult rat kidneys

1990 • 123 citations

Renin, angiotensins, and angiotensin-converting enzyme in neuroblastoma cells: evidence for intracellular formation of angiotensins.

1981 • 122 citations

Identification and characterization of angiotensin II receptor subtypes in rabbit ventricular myocardium

1990 • 122 citations

Identification and characterization of the rabbit angiotensin II myocardial receptor.

1984 • 122 citations

The ovarian renin-angiotensin system: Renin-like activity and angiotensin II/III immunoreactivity in gonadotropin-stimulated and unstimulated human follicular fluid

1987 • 117 citations

Structure, expression, and regulation of the murine renin genes.

1991 • 115 citations

Localization of angiotensin II receptors in ovarian follicles and the identification of angiotensin II in rat ovaries.

1987 • 114 citations

Arterial wall uptake of renal renin and blood pressure control.

1983 • 111 citations

Evidence for an intrinsic angiotensin system in the canine pancreas

1991 • 109 citations

Human prorenin.

1991 • 108 citations

Localization of brain angiotensinogen mRNA by hybridization histochemistry

1987 • 108 citations

Angiotensin II receptors in chromatin fragments generated by micrococcal nuclease

1984 • 106 citations

Renin and Angiotensin: the Complete System Within the Neuroblastoma × Glioma Cell

1981 • 102 citations

Immunocytochemistry of the renin-angiotensin system: renin, angiotensinogen, angiotensin I, angiotensin II, and converting enzyme in the kidneys of mice, rats, and tree shrews.

1982 • 95 citations

Angiotensin II in rat brain comigrates with authentic angiotensin II in high pressure liquid chromatography.

1985 • 92 citations

Angiotensinogen gene expression in extrahepatic rat tissues: Application of a solution hybridization assay

1988 • 90 citations

Tissue Renin-Angiotensin System

1987 • 90 citations

Tissue Renin-Angiotensin Systems: Focus on the Heart

1987 • 88 citations

The Brain Renin-Angiotensin System: Localization and General Significance

1992 • 87 citations

INCREASED CARDIAC ANGIOTENSIN‐CONVERTING ENZYME IN RATS WITH CHRONIC HEART FAILURE

1990 • 84 citations

Human ovarian theca cells are a source of renin.

1988 • 83 citations

Angiotensin II binding sites in the conduction system of rat hearts

1987 • 83 citations

Discrimination of angiotensin II receptor subtype distribution in the rat brain using non-peptidic receptor antagonists

1991 • 82 citations

Binding Sites for Angiotensin II in Human Mononuclear Leucocytes1

1978 • 80 citations

Autoradiographic localization of mas proto-oncogene mRNA in adult rat brain using in situ hybridization

1990 • 76 citations

Characterization of the rabbit ventricular myocardial receptor for angiotensin II. Evidence for two sites of different affinities and specificities.

1983 • 74 citations

Distinct angiotensin II receptor in primary cultures of glial cells from rat brain.

1987 • 71 citations

Suppression of the vascular response to injury: The role of angiotensin-converting enzyme inhibitors

1991 • 71 citations

Adrenal Renin: A Possible Regulator of Aldosterone Production

1983 • 70 citations

Action of atrial natriuretic peptide and angiotensin II on the myocardium: Studies in isolated rat ventricular cardiomyocytes

1989 • 68 citations

Regulation of renin angiotensins by gonadotropic hormones in cultured murine Leydig tumor cells. Release of angiotensin but not renin.

1986 • 68 citations

Quantification of renin mRNA in various mouse tissues by a novel solution hybridization assay

1988 • 67 citations

Presence of renin in primary neuronal and glial cells from rat brain

1987 • 63 citations

Sulfhydryl reducing agents distinguish two subtypes of angiotensin II receptors in the rat brain

1991 • 62 citations

Regulation of liver angiotensinogen and kidney renin mRNA levels by angiotensin II

1990 • 62 citations

Renin Gene Expression in Rat Tissues: A New Quantitative Assay Method for Rat Renin mRNA Using Synthetic cRNA

1988 • 58 citations

Angiotensinogen is secreted by pure rat neuronal cell cultures

1992 • 56 citations

Molecular cloning of human angiotensinogen cDNA and evidence for the presence of its mRNA in rat heart.

1987 • 53 citations

Genetic control of renin activity in the submaxillary gland of the mouse.

1977 • 51 citations

Immunoreactive renin in mouse adrenal gland. Localization in the inner cortical region.

1984 • 51 citations

Altered sodium regulation of renal angiotensinogen mRNA in the spontaneously hypertensive rat

1989 • 50 citations

Rat brain cells in primary culture: Characterization of angiotensin II binding sites

1981 • 50 citations

The myocardial intracellular renin-angiotensin system

1987 • 48 citations

Changes in gene expression of the renin???angiotensin system in two-kidney, one clip hypertensive rats

1991 • 47 citations

Renin in the human kidney

1981 • 44 citations

Detection of Renin Messenger RNA in Rat Tissues: Increased Sensitivity Using an RNAse Protection Technique

1987 • 42 citations

Immunocytochemical and Biochemical Characterization of Angiotensin I and II in Cultured Neuronal and Glial Cells from Rat Brain

1988 • 41 citations

Angiotensin II stimulation of plasminogen activator inhibitor-1 gene expression in astroglial cells from the brain.

1992 • 40 citations

Renin release regulation during acute renin inhibition in normal volunteers.

1991 • 39 citations

The AT2 angiotensin receptor subtype predominates in the 18 day gestation fetal rat brain

1991 • 39 citations

Tissue Renin—Angiotensin Systems

1991 • 38 citations

Hypothalamic angiotensinergic fibre systems terminate in the neurohypophysis

1989 • 38 citations

Release of immunoreactive angiotensin II from neuronal cultures: adrenergic influences

1989 • 37 citations

Enhanced cardiac angiotensinogen gene expression and angiotensin converting enzyme activity in tachypacing-induced heart failure in rats

1991 • 36 citations

Molecular biology of renin I: Gene and protein structure, synthesis and processing

1992 • 36 citations

Evidence that angiotensin II is a paracrine agent mediating gonadotrophin-releasing hormone-stimulated inositol phosphate production and prolactin secretion in the rat

1988 • 33 citations

Tissue Renin—Angiotensin Systems

1991 • 32 citations

Isolation of renin-rich rat kidney cells.

1987 • 29 citations

Expression of angiotensin converting enzyme mRNA in rat brain

1991 • 29 citations

Effect of angiotensin II on renin production by rat adrenal glomerulosa cells in culture.

1992 • 28 citations

Renin in the Brain and Neuroblastoma Cells: An Endogenous and Intracellular System

1982 • 27 citations

The effect of chronic bilateral nephrectomy on plasma and brain angiotensin

1992 • 26 citations

Alterations of lymphocyte populations during development in the spontaneously hypertensive rat

1992 • 24 citations

Cellular mechanisms of growth in cardiovascular tissue

1987 • 24 citations

Renin in the Rat Pituitary Coexists with Angiotensin II and Depends on Testosterone*

1986 • 23 citations

The Angiotensin I-Converting Enzyme (Kininase II)

1990 • 23 citations

Biosynthesis of Angiotensinogen and Angiotensins by Brain Cells in Primary Culture

1988 • 21 citations

Molecular biology of renin II: Gene control by messenger RNA, transfection and transgenic studies

1992 • 21 citations

The Angiotensin I-Converting Enzyme (Kininase II)

1990 • 20 citations

Significance of vascular renin for local generation of angiotensins.

1991 • 20 citations

Purification of renin and prorenin.

1991 • 17 citations

Suppression of Renin-Angiotensin System in the Heart of Spontaneously Hypertensive Rats

1987 • 16 citations

Characterization of angiotensin II receptor subtypes in the rat kidney and heart using the non-peptide antagonists DuP753 and PD123 177

1991 • 14 citations

Measurement of Brain Peptides: Angiotensin and Atrial Natriuretic Peptide in Tissue and Cell Culture

1991 • 14 citations

Autoradiographic localization and characterization of angiotensin II binding sites in the spleen of rats and mice

1987 • 12 citations

Angiotensin Peptides in Brain and Pituitary of Rat and Sheep

1992 • 12 citations

Angiotensin II stimulation of plasminogen activator inhibitor-1 gene expression in astroglial cells from the brain

1992 • 11 citations

<b>LOCALIZATION OF RENIN mRNA IN THE MOUSE SUBMANDIBULAR GLAND BY <i>IN SITU</i> HYBRIDIZATION </b><b>HISTOCHEMISTRY </b>

1983 • 10 citations

Molecular and Cell Biology of Angiotensin Receptors

1991 • 8 citations

Electrophysiological expression of endothelin and angiotensin receptors in Xenopus oocytes injected with rat heart mRNA

1989 • 7 citations

Molecular and Cell Biology of Angiotensin Receptors

1991 • 7 citations

Distinct Localization of Renin and Angiotensins in Separate Subcellular Fractions of the Rat Adrenal Cortex.

1991 • 4 citations

Renin purification and cloning.

1991 • 4 citations

Chromatographic methods for characterization of angiotensin in brain tissue

1989 • 2 citations

Deleted Work

1955 • 0 citations