DNA repair in cultured human fibroblasts does not decline with donor age

DNA Repair in Bacteria and Mammalian Cells

1979 • 854 citations

DNA Damage as the Primary Cause of Aging

1981 • 248 citations

Evidence for an adaptive DNA repair pathway in CHO and human skin fibroblast cell lines

1980 • 218 citations

Age-Associated Changes in the DNA of Mouse Tissue

1971 • 203 citations

Psoralen monoadducts and interstrand cross-links in DNA

1971 • 199 citations

Pyrimidine dimer formation and repair in human skin.

1980 • 178 citations

Defect in DNA Synthesis in Skin of Patients with Xeroderma Pigmentosum Demonstrated in vivo

1970 • 147 citations

The influence of caffeine on cell survival in excision-proficient and excision-deficient xeroderma pigmentosum and normal human cell strains following ultraviolet-light irradiation

1975 • 140 citations

Age-related decrease of ultraviolet light-induced DNA repair synthesis in human peripheral leukocytes.

1979 • 129 citations

Rate of DNA repair in progeric and normal human fibroblasts

1974 • 90 citations

Is the ability to repair damage to DNA related to the proliferative capacity of a cell? The rejoining of X-ray-produced strand breaks

1973 • 83 citations

Rate and extent of DNA repair in nondividing human diploid fibroblasts.

1981 • 83 citations

The kinetics of thymine dimer excision in ultraviolet-irradiated human cells

1978 • 81 citations

Single-stranded regions in DNA of old mice

1975 • 78 citations

Age-dependent excision repair of damaged thymine from γ-irradiated DNA by isolated nuclei from human fibroblasts

1975 • 72 citations

Time course of O6-methylguanine removal from DNA of N-methyl-N-nitrosourea-treatedhuman fibroblasts

1981 • 69 citations

Relationship between DNA Repair Capacity and Cellular Aging

1976 • 63 citations

Repair of X-ray damage in aging WI-38 cells

1974 • 61 citations

Repair by human cells of adenovirus-2 damaged by psoralen plus near ultraviolet light treatment

1975 • 57 citations

Decreased repair of gamma ray damaged DNA in progeria

1977 • 44 citations

In vivo repair of rat intestinal dna damage by alkylating agents

2006 • 36 citations

DNA Repair Processes Protect Human Beings from Premature Solar Skin Damage: Evidence from Studies on Xeroderma Pigmentosum

1979 • 34 citations

Evidence for repair of ultraviolet light-damaged herpes virus in human fibroblasts by a recombination mechanism

1980 • 33 citations

Effect of low dose rate ionizing radiation on the division potential of cells in vitro

1977 • 33 citations

Repair of X-ray-induced DNA damage in aging human diploid cells

1980 • 32 citations

Defective reactivation of ultraviolet light-irradiated herpesvirus by a Bloom's syndrome fibroblast strain.

1979 • 30 citations

Aging and sister chromatid exchange I. The effect of aging on mitomycin-C induced sister chromatid exchange frequencies in mouse and rat bone marrow cells in vivo

1978 • 24 citations

Evidence for an increased level of DNA damage in high doubling level human diploid cells in culture

1981 • 24 citations

DNA repair synthesis in rat retinal ganglion cells treated with chemical carcinogens or ultraviolet light in vitro, with special reference to aging and repair level.

1978 • 22 citations

Host-cell reactivation of UV-irradiated and chemically-treated herpes simplex virus-1 by xeroderma pigmentosum, XP heterozygotes and normal skin fibroblasts

1978 • 22 citations

Repair of psoralen-treated DNA by genetic recombination in human cells infected with herpes simplex virus.

1981 • 21 citations

The effect of hamster age on u.v.-induced unscheduled DNA synthesis in freshly isolated lung and kidney cells

1981 • 16 citations

Changes in DNA alkali-sensitive sites during senescence and establishment of fibroblasts in vitro

1980 • 13 citations

Enhanced transformation of xeroderma pigmentosum variant cells by ultraviolet light-irradiated simian virus 40.

1979 • 7 citations