The mechanism of alkylation of DNA by 5-(3-methyl-l-triazeno) imidazole-4-carboxamide (MIC), a metabolite of dic (NSC-45388) non-involvement of diazomethane

Reagents for Organic Synthesis

1976 • 2,388 citations

Reagents for Organic Synthesis

1967 • 1,492 citations

Carcinogenic Nitroso Compounds

1967 • 1,109 citations

The structure of ribonucleic acids. 1. Cyclic nucleotides produced by ribonuclease and by alkaline hydrolysis

1952 • 780 citations

Mass spectrometry : organic chemical applications

1962 • 641 citations

Use of the glass electrode in deuterium oxide and the relation between the standardized pD (paD) scale and the operational pH in heavy water

1968 • 624 citations

Mechanisms of chemical carcinogenesis: nature of proximate carcinogens and interactions with macromolecules.

1966 • 489 citations

Chemical ionization mass spectrometry

1968 • 204 citations

Mass spectra of nucleic acid derivatives. II. Guanine, adenine, and related compounds

1967 • 182 citations

Mechanism of Alkylation of Nucleic Acids by Nitrosodimethylamine

1968 • 162 citations

Imidazoles. I. Coupling Reactions of 5-Diazoimidazole-4-carboxamide^1,2

1962 • 135 citations

5-(3,3-dimethyl-1-triazeno)-imidazole-4-carboxamide (DTIC, DIC, NSC-45388)—A new antitumor agent with activity against malignant melanoma

1972 • 119 citations

Interpretation of NMR Spectra

1965 • 116 citations

Mechanism of carcinogenesis with 1-Aryl-3,3-dialkyltriazenes. Enzymatic dealkylation by rat liver microsomal fraction in vitro

1969 • 110 citations

Chemical Ionization Mass Spectrometry

1972 • 100 citations

N-demethylation the antineoplastic agent4(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide by rats and man.

1970 • 98 citations

Antitumor activity of triazenoimidazoles

1962 • 82 citations

Photochemical Experiments in Rigid Media at Low Temperatures. II. The Reactions of Methylene, Cyclopentadienylene and Diphenylmethylene

1959 • 81 citations

Methylation of DNA by 3H-14C-methyl-labelled N-methyl-N-nitrosourea—Evidence for transfer of the intact methyl group

1973 • 72 citations

Sign of Geminal HH Coupling Constants in Methanes and the Effect of Substitution

1962 • 67 citations

Reaction of alkylating mutagens and carcinogens with nucleic acids: N-3 of guanine as a site of alkylation by N-methyl-N-nitrosourea and dimethyl sulphate

1972 • 63 citations

Methylation of nucleic acids and urinary excretion of 14C-labeled 7-methylguanine by rats and man after administration of 4(5)-(3,3-Dimethyl-1-triazeno)-imidazole 5(4)-carboxomide

1971 • 62 citations

Decomposition of Methylazoxymethanol, the Aglycone of Cycasin, in D2O

1972 • 53 citations

THE CONVERSION OF QUATERNARY PYRROLIDINIUM SALTS TO OPEN-CHAIN DIAMINES

1944 • 50 citations

Mechanism of action of 5-(3,3-dimethyl-1-triazeno)imidazole-4-caboxamide in mammalian cells in culture

1972 • 47 citations

Imidazoles. II. 5(or 4)-(Monosubstituted Triazeno)imidazole-4(or 5)-carboxamides¹

1966 • 45 citations

Metabolism of 4(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide to 4(5)-aminoimidazole-5(4)-carboxamide in man

1970 • 36 citations

Alkylation of Nucleic Acids of Rat Liver and Lung by Deuterated <italic>N</italic>-Nitrosodiethylamine <italic>In Vivo</italic><xref ref-type="fn" rid="FN1">2</xref>

1971 • 33 citations

The mode of action of N-methyl-N′-nitro-N-nitrosoguanidine in mutagenesis

1972 • 32 citations

Disposition of 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide, a new antitumor agent.

1971 • 26 citations

Metabolism of 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (NSC-45388) in human and animal tumor tissue.

1972 • 19 citations

A convenient method for the production of diazomethane-2

1972 • 14 citations

Antitumor activity of 4 (or 5)-aminoimidazole-5 (or 4)-carboxamide derivatives.

1965 • 14 citations

Further investigation on the carcinostatic activity of 4(or 5)-aminoimidazole-5(or 4)-carboxamide derivatives: structure-activity relationship.

1968 • 6 citations