Constitutive activation of PI3K is involved in the spontaneous proliferation of primary acute myeloid leukemia cells: direct evidence of PI3K activation

JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis

2004 • 659 citations

Survival of acute myeloid leukemia cells requires PI3 kinase activation

2003 • 470 citations

Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product

1998 • 456 citations

The Raf/MEK/ERK signal transduction cascade as a target for chemotherapeutic intervention in leukemia

2002 • 249 citations

Src transduces erythropoietin-induced differentiation signals through phosphatidylinositol 3-kinase

2001 • 64 citations

CD28 cross-linking augments TCR-mediated signals and costimulates superantigen responses.

1995 • 33 citations

The role of phosphatidylinositol 3'-kinase and its downstream signals in erbB-2-mediated transformation.

2003 • 31 citations