Dynorphin increases in the dorsal spinal cord in rats with a painful peripheral neuropathy

A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man

1988 • 5,129 citations

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

1988 • 4,963 citations

Autotomy following peripheral nerve lesions: experimental anesthesia dolorosa

1979 • 651 citations

Further evidence for ‘pain-related’ behaviours in a model of unilateral peripheral mononeuropathy

1990 • 504 citations

The somatotopic organization of primary afferent terminals in the superficial laminae of the dorsal horn of the rat spinal cord

1985 • 446 citations

Enhancement of dynorphin gene expression in spinal cord following experimental inflammation: stimulus specificity, behavioral parameters and opioid receptor binding

1988 • 435 citations

Unilateral inflammation of the hindpaw in rats as a model of prolonged noxious stimulation: Alterations in behavior and nociceptive thresholds

1988 • 338 citations

κ-Opioid receptors and analgesia

1990 • 318 citations

Temporal analysis of increases in c-fos, preprodynorphin and preproenkephalin mRNAs in rat spinal cord

1989 • 311 citations

In situ hybridization histochemistry and immunocytochemistry reveal an increase in spinal dynorphin biosynthesis in a rat model of peripheral inflammation and hyperalgesia.

1988 • 292 citations

Deafferentation and chronic pain in animais: An evaluation of evidence suggesting autotomy is related to pain

1986 • 234 citations

Evidence that adjuvant arthritis in the rat is associated with chronic pain

1987 • 203 citations

Inflammation of the hind limb as a model of unilateral, localized pain: influence on multiple opioid systems in the spinal cord of the rat

1988 • 195 citations

Processing of Sensory Information in the Superficial Dorsal Horn of the Spinal Cord

1989 • 195 citations

Immunocytochemical analysis of serotonergic axons in laminae I and II of the lumbar spinal cord of the cat

1982 • 158 citations

Deafferentation in animals as a model for the study of pain: an alternative hypothesis

1984 • 143 citations

Prodynorphin gene expression is enhanced in the spinal cord of chronic arthritic rats

1987 • 122 citations

Opioid peptide immunoreactivity in spinal and trigeminal dorsal horn neurons projecting to the parabrachial nucleus in the rat

1986 • 121 citations

A model of chronic pain in the rat: functional correlates of alterations in the activity of opioid systems

1987 • 116 citations

Neurochemical and Anatomical Changes in the Dorsal Horn of Rats with an Experimental Painful Peripheral Neuropathy

1989 • 114 citations

Changes in dynorphin, enkephalin and cholecystokinin content of hippocampus and substantia nigra after amygdala kindling

1986 • 113 citations

Comparison of met‐enkephalin‐, dynorphin A‐, and neurotensin‐immunoreactive neurons in the cat and rat spinal cords: I. Lumbar cord

1987 • 103 citations

Induction of the gene encoding pro-dynorphin by experimentally induced arthritis enhances staining for dynorphin in the spinal cord of rats

1989 • 103 citations

Peripheral inflammation is associated with increased dynorphin immunoreactivity in both projection and local circuit neurons in the superficial dorsal horn of the rat lumbar spinal cord

1989 • 99 citations

Strychnine-enhanced transsynaptic degeneration of dorsal horn neurons in rats with an experimental painful peripheral neuropathy

1989 • 74 citations

The influence of foot-shock stress upon brain, pituitary and spinal cord pools of immunoreactive dynorphin in rats

1981 • 70 citations

The influence of chronic stress on multiple opioid peptide systems in the rat: pronounced effects upon dynorphin in spinal cord

1987 • 68 citations

Immunocytochemical identification of long ascending, peptidergic lumbar spinal neurons terminating in either the medial or lateral thalamus in the rat

1988 • 62 citations

Increased staining of immunoreactive dynorphin cell bodies in the deafferented spinal cord of the rat

1988 • 61 citations

Increased spinal cord dynorphin mRNA during peripheral inflammation.

1986 • 44 citations

Influence of dynorphin (1-13) on spinal reflexes in the rat.

1988 • 39 citations

Opioid peptide gene expression in rat trigeminal nucleus caudalis neurons: Normal distribution and effects of trigeminal deafferentation

1988 • 30 citations

Progress in opioid research. Proceedings of the 1986 International Narcotics Research Conference.

1986 • 6 citations