Classification system based on the functional equivalency of mitogens that regulate WI-38 cell proliferation*1

Methods in Enzymology , Vol

1966 • 26,261 citations

125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts.

1976 • 1,293 citations

Stimulation of tyrosine-specific phosphorylation by platelet-derived growth factor

1982 • 675 citations

Cellular senescence and DNA synthesis

1973 • 537 citations

Epidermal growth factor stimulates phosphorylation in membrane preparations in vitro

1978 • 448 citations

Monoclonal antibodies to receptors for insulin and somatomedin-C.

1983 • 423 citations

Somatomedin-C stimulates the phosphorylation of the beta-subunit of its own receptor.

1983 • 395 citations

RU 38486: Potent antiglucocorticoid activity correlated with strong binding to the cytosolic glucocorticoid receptor followed by an impaired activation

1984 • 372 citations

Epidermal growth factor (EGF) and somatomedin C regulate G1 progression in competent BALB/c-3T3 cells

1982 • 318 citations

Improved medium for clonal growth of human diploid fibroblasts at low concentrations of serum protein

1977 • 272 citations

Evidence from Monoclonal Antibody Studies that Insulin Stimulates Deoxyribonucleic Acid Synthesis through the Type I Somatomedin Receptor*

1985 • 160 citations

Association of bovine brain-derived growth factor receptor with protein tyrosine kinase activity.

1986 • 151 citations

The Type II Insulin-Like Growth Factor Receptor Does Not Mediate Deoxyribonucleic Acid Synthesis in Human Fibroblasts*

1987 • 108 citations

Initiation of proliferative events by human α‐thrombin requires both receptor binding and enzymic activity

1984 • 85 citations

Similar action of platelet‐derived growth factor and epidermal growth factor in the prereplicative phase of human fibroblasts suggests a common intracellular pathway

1985 • 79 citations

Insulin‐like growth factor I/somatomedin‐C (IGF‐I/SM‐C) and glucocorticoids synergistically regulate mitosis in competent human fibroblasts

1983 • 70 citations

Growth regulation of WI38 cells in a serum-free medium

1981 • 69 citations

Insulin‐like growth factor‐I: Specific binding to high and low affinity sites and mitogenic action throughout the life span of WI‐38 cells

1987 • 67 citations

Primary culture of human diploid cells and its long-term transfer in a serum-free medium

1981 • 56 citations

Multiplication of human diploid fibroblasts in a synthetic medium supplemented with EGF, insulin, and dexamethasone

1981 • 56 citations

Changes in Specific Dexamethasone Binding during Aging in WI-38 Cells*

1981 • 49 citations

Growth of human foreskin fibroblasts in a serum-free, defined medium without platelet-derived growth factor

1982 • 35 citations

Multiplication of Swiss 3T3 cells in a serum-free medium

1983 • 35 citations

The effect of dexamethasone on epidermal growth factor binding and stimulation of proliferation in young and senescent WI38 cells

1986 • 22 citations

Control of entry of Swiss 3T3 cells into S phase by fibroblast growth factor under serum-free conditions

1983 • 19 citations