Prevention of ozone-induced airway hyperresponsiveness and epithelial injury by phosphodiesterase inhibitors in guinea pigs

The biology of nitrogen oxides in the airways.

1994 • 928 citations

Mechanisms of radical formation from reactions of ozone with target molecules in the lung

1994 • 287 citations

Ozone Concentration and Pulmonary Response Relationships for 6.6-Hour Exposures with Five Hours of Moderate Exercise to 0.08, 0.10, and 0.12 ppm

1990 • 213 citations

Ozone-induced release of cytokines and fibronectin by alveolar macrophages and airway epithelial cells

1994 • 176 citations

The effects of salmeterol and salbutamol on ciliary beat frequency of cultured human bronchial epithelial cells, in vitro

1992 • 125 citations

Ozone-induced Augmentation of Eicosanoid Metabolism in Epithelial Cells from Bovine Trachea

1988 • 111 citations

Protective role of epithelium in the guinea pig airway

1989 • 99 citations

Ozone-induced Bronchial Hyperresponsiveness in the Rat Is Not Accompanied by Neutrophil Influx or Increased Vascular Permeability in the Trachea

1988 • 96 citations

Effect of cAMP on ciliary function in rabbit tracheal epithelial cells

1989 • 85 citations

Novel Selective PDE IV Inhibitors as Antiasthmatic Agents. Synthesis and Biological Activities of a Series of 1-Aryl-2,3-bis(hydroxymethyl)naphthalene Lignans

1996 • 55 citations

Mechanisms contributing to ozone-induced bronchial hyperreactivity in guinea-pigs

1992 • 50 citations

Ozone-induced airway hyperreactivity in the guinea pig

1984 • 47 citations

Expression of inducible nitric oxide synthase mRNA in Brown Norway rats exposed to ozone: effect of dexamethasone

1995 • 43 citations

Role of tachykinins in ozone-induced acute lung injury in guinea pigs

1993 • 37 citations

Phosphodiesterase IV inhibitors as therapy for eosinophil-induced lung injury in asthma.

1994 • 31 citations

The Effect of Antioxidants on Ozone-induced Airway Hyperresponsiveness in Dogs

1991 • 31 citations

Phosphodiesterase-IV inhibition, respiratory muscle relaxation and bronchodilation by WAY-PDA-641.

1994 • 30 citations

Effect of an anti-Mo1 MAb on ozone-induced airway inflammation and airway hyperresponsiveness in dogs

1992 • 25 citations

Interleukin-5 production by peripheral blood mononuclear cells of asthmatic patients is suppressed by T-440: relation to phosphodiesterase inhibition.

1996 • 22 citations

Importance of Impairment of the Airway Epithelium for Ozone-Induced Airway Hyperresponsiveness in Guinea Pigs

1995 • 17 citations

Stimulation of nitric oxide production in rat lung lavage cells by anti-Mac-1beta antibody: effects of ozone inhalation.

1996 • 11 citations

A 5-lipoxygenase inhibitor, FR110302, inhibits ozone-induced airway hyperresponsiveness in guinea pigs and dogs

1993 • 10 citations

Inhibitory Effect of a Novel Phosphodiesterase IV Inhibitor, T-440, on Antigen- and Chemical Mediator-Induced Bronchoconstrictions in Guinea Pigs In Vivo

1996 • 10 citations

Physiologic Significance of Epithelial Removal on Guinea Pig Tracheal Smooth Muscle Response to Acetylcholine and Serotonin

1993 • 10 citations

Turbulence effects upon the NO2NO conversion in the vicinity of an urban area

1996 • 9 citations

Prostaglandin E2 Attenuates Hyperoxia-induced Injury in Cultured Rabbit Tracheal Epithelial Cells

1992 • 8 citations

The pharmacology of the respiratory epithelium

1992 • 5 citations