An age-related spatial learning deficit: Choline uptake distinguishes “impaired” and “unimpaired” rats

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Place navigation impaired in rats with hippocampal lesions

1982 • 6,277 citations

Hippocampal connections and spatial discrimination

1978 • 836 citations

A behavioural analysis of spatial localization following electrolytic, kainate- or colchicine-induced damage to the hippocampal formation in the rat

1983 • 590 citations

SODIUM‐DEPENDENT HIGH AFFINITY CHOLINE UPTAKE: A REGULATORY STEP IN THE SYNTHESIS OF ACETYLCHOLINE

1976 • 542 citations

Medial septal area lesions disrupt theta rhythm and cholinergic staining in medial entorhinal cortex and produce impaired radial arm maze behavior in rats

1982 • 390 citations

An evaluation of spatial information processing in aged rats.

1987 • 353 citations

Long-term enhancement of hippocampal synaptic transmission and the acquisition of spatial information

1986 • 325 citations

Cholinergic receptor blockade impairs spatial localization by use of distal cues in the rat.

1982 • 301 citations

Cholinergic receptor blockade in the rat impairs locale but not taxon strategies for place navigation in a swimming pool.

1985 • 270 citations

Spatial learning deficits in old rats: A model for memory decline in the aged

1988 • 255 citations

Regional changes in brain glucose metabolism reflect cognitive impairments in aged rats

1984 • 246 citations

Cholinergic receptor blockade in the rat impairs locale but not taxon strategies for place navigation in a swimming pool.

1985 • 242 citations

Loss of perforated synapses in the dentate gyrus: morphological substrate of memory deficit in aged rats.

1986 • 231 citations

Aging and the physiology of spatial memory

1988 • 217 citations

Aged rats need a preserved complement of perforated axospinous synapses per hippocampal neuron to maintain good spatial memory

1986 • 149 citations

Effects of training on a spatial memory task on high affinity choline uptake in hippocampus and cortex in young adult and aged rats

1988 • 124 citations

Behavior alters the uptake of [3h]choline into acetylcholinergic neurons of the nucleus basalis magnocellularis and medial septal area

1984 • 101 citations

Aging of membrane transport mechanisms in the central nervous system — high affinity choline transport in rat cortical synaptosomes

1985 • 21 citations

Strain specific alterations in hippocampal cholinergic function following acute footshock

1980 • 18 citations