Monoclonal lupus autoantibody secretion by human-human hybridomas. Selection of hybrids by conventional and novel techniques.

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

Mixed connective tissue disease-an apparently distinct rheumatic disease syndrome associated with a specific antibody to an extractable nuclear antigen (ENA)

1972 • 1,816 citations

The Anatomy of A-, B-, and Z-DNA

1982 • 645 citations

Polyspecificity of Monoclonal Lupus Autoantibodies Produced by Human-Human Hybridomas

1983 • 453 citations

Human-human hybridomas producing monoclonal antibodies of predefined antigenic specificity.

1980 • 383 citations

Production of human hybridomas secreting antibodies to measles virus

1980 • 308 citations

Production of autoantibodies by human-human hybridomas.

1982 • 228 citations

Increased immunoglobulin-secreting cells in the blood of patients with active systemic lupus erythematosus

1980 • 178 citations

Antigen-binding diversity and idiotypic cross-reactions among hybridoma autoantibodies to DNA.

1981 • 171 citations

Anti-DNA autoantibodies in (NZB X NZW)F1 mice are clonally heterogeneous, but the majority share a common idiotype.

1982 • 143 citations

Use of monoclonal antibodies to identify shared idiotypes on human antibodies to native DNA from patients with systemic lupus erythematosus.

1983 • 127 citations

Dna isolated from DNA/anti-DNA antibody immune complexes in systemic lupus erythematosus is rich in guanine-cytosine content.

1982 • 126 citations

THE ANTIGENIC DETERMINANTS OF DENATURED DNA REACTIVE WITH LUPUS ERYTHEMATOSUS SERUM

1962 • 124 citations

Immunopathogenesis of Systemic Lupus Erythematosus

1974 • 113 citations

Reaction of systemic lupus erythematosus antinative DNA antibodies with native DNA fragments from 20 to 1,200 base pairs.

1980 • 107 citations

Measurement of anti-double-stranded DNA antibodies in major immunoglobulin classes

1979 • 92 citations

The isolation of heterokaryons and hybrids by a selective system using irreversible biochemical inhibitors

1978 • 90 citations

Double-Helical Polynucleotides: Immunochemical Recognition of Differing Conformations

1970 • 89 citations

Avidity of antibodies to dsDNA: comparison of IFT on Crithidia luciliae, Farr assay, and PEG assay.

1982 • 88 citations

Antibodies to denatured deoxyribonucleic acid in lupus erythematosus serum II. Characterization of antibodies in several sera

1962 • 82 citations

T cell abnormalities in NZB mice occur independently of autoantibody production.

1981 • 77 citations

Anti DNA antibody production by lymphoid cells of mice and human systemic lupus erythematosus (SLE)

1973 • 55 citations

Antibodies to denatured deoxyribonucleic acid in lupus erythematosus serum. IV. Evidence for purine determinants in DNA

1963 • 53 citations

Antibodies to double-stranded DNA: purification and characterization of binding specificities.

1980 • 51 citations

A sensitive solid phase microradioimmunoassay for anti‐double stranded DNA antibodies

1981 • 50 citations

Specific anti-influenza virus antibody production in vitro by human peripheral blood mononuclear cells.

1981 • 49 citations

CLINICAL SIGNIFICANCE OF ANTI–DOUBLE‐STRANDED DNA ANTIBODIES DETECTED BY A SOLID PHASE ENZYME IMMUNOASSAY

1981 • 40 citations

The Production of Antibodies to Mononucleotides, Oligonucleotides, and DNA

1968 • 37 citations

The Production of Antibodies to Mononucleotides, Oligonucleotides and DNA

1966 • 26 citations

An assay for human lymphocyte mitogenic factor: B-lymphocyte stimulation by a T-lymphocyte product

1978 • 14 citations

Immunoglobulin-secreting cells in SLE: correlation with disease activity.

1980 • 13 citations

Anti-poly(G)·poly(C) antibodies in the serum of patients with systemic lupus erythematosus

1982 • 6 citations

[Effect of the secondary structure of polynucleotides on their immunological reaction].

1967 • 3 citations

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