Recycling of the asialoglycoprotein receptor and the effect of lysosomotropic amines in hepatoma cells.

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

1978 • 2,146 citations

Carbohydrate-Specific Receptors of the Liver

1982 • 1,895 citations

Endocytosis and the recycling of plasma membrane.

1983 • 1,447 citations

125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts.

1976 • 1,293 citations

Intracellular site of asialoglycoprotein receptor-ligand uncoupling: Double-label immunoelectron microscopy during receptor-mediated endocytosis

1983 • 816 citations

Chloroquine inhibits lysosomal enzyme pinocytosis and enhances lysosomal enzyme secretion by impairing receptor recycling.

1980 • 743 citations

Effect of weak bases on the intralysosomal pH in mouse peritoneal macrophages.

1981 • 736 citations

Rapid acidification of endocytic vesicles containing α2-macroglobulin

1982 • 672 citations

PROTEIN DEGRADATION IN CULTURED CELLS

1974 • 603 citations

Monensin interrupts the recycling of low density lipoprotein receptors in human fibroblasts

1981 • 593 citations

Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts.

1982 • 569 citations

Kinetics of internalization and recycling of transferrin and the transferrin receptor in a human hepatoma cell line. Effect of lysosomotropic agents.

1983 • 558 citations

Kinetics of internalization and recycling of the asialoglycoprotein receptor in a hepatoma cell line.

1982 • 357 citations

Acidification of macrophage and fibroblast endocytic vesicles in vitro.

1983 • 331 citations

Characterization of the asialoglycoprotein receptor in a continuous hepatoma line.

1981 • 273 citations

Chloroquine and ammonium ion inhibit receptor-mediated endocytosis of mannose-glycoconjugates by macrophages: Apparent inhibition of receptor recycling

1980 • 252 citations

Mannose-specific endocytosis receptor of alveolar macrophages: demonstration of two functionally distinct intracellular pools of receptor and their roles in receptor recycling.

1982 • 211 citations

The asialoglycoprotein receptor internalizes and recycles independently of the transferrin and insulin receptors

1983 • 161 citations

Monensin inhibits intracellular dissociation of asialoglycoproteins from their receptor.

1983 • 157 citations

Chloroquine reduces the number of asialo-glycoprotein receptors in the hepatocyte plasma membrane

1979 • 144 citations

Difficulties in the quantification of asialoglycoprotein receptors on the rat hepatocyte.

1980 • 123 citations

Biosynthesis of the human asialoglycoprotein receptor.

1983 • 119 citations

Identification and quantification of the rat hepatocyte asialoglycoprotein receptor.

1981 • 88 citations

Analysis of the effect of amines on inhibition of receptor-mediated and fluid-phase pinocytosis in rabbit alveolar macrophages

1981 • 88 citations

Inhibition of the degradation of receptor-bound human choriogonadotropin by lysosomotropic agents, protease inhibitors, and metabolic inhibitors

1978 • 87 citations

Inhibition of receptor-mediated uptake of a lysosomal enzyme into fibroblasts by chloroquine, procaine and ammonia

1979 • 85 citations

Recycling of Cell-surface Receptors: Observations from the LDL Receptor System

1982 • 83 citations

The effects of ammonium ions and chloroquine on uptake and degradation of 125I-labeled asialo-fetuin in isolated rat hepatocytes

1980 • 71 citations

Evidence for transmembrane modulation of the ligand-binding site of the hepatocyte galactose/N-acetylgalactosamine-specific receptor.

1983 • 44 citations

The effects of low temperature and chloroquine on 125I-insulin degradation by the perfused rat liver

1981 • 14 citations