Ca2+ as messenger of 5HT2-receptor stimulation in human blood platelets

Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves.

1978 • 2,400 citations

Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator.

1982 • 2,255 citations

A non-disruptive technique for loading calcium buffers and indicators into cells

1981 • 1,121 citations

Enzyme changes in neonatal skeletal muscle: effect of thyroid deficiency

1978 • 1,103 citations

[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role.

1982 • 1,049 citations

Forskolin: a unique diterpene activator of cyclic AMP-generating systems.

1981 • 716 citations

Two Distinct Central Serotonin Receptors with Different Physiological Functions

1981 • 640 citations

A nonlinear regression program for small computers

1981 • 563 citations

Cytoplasmic free Ca²⁺ in human platelets: Ca²⁺ thresholds and Ca‐independent activation for shape‐change and secretion

1982 • 537 citations

Adenylate cyclase assay.

1979 • 485 citations

Stimulation of calcium uptake in platelet membrane vesicles by adenosine 3′,5′-cyclic monophosphate and protein kinase

1977 • 311 citations

Advances in cyclic nucleotide research Vol. 14

1982 • 225 citations

The cytoplasmic concentration of free calcium in platelets is controlled by stimulators of cyclic AMP production (PGD2, PGE1, forskolin)

1983 • 217 citations

Inhibition of 5-hydroxytryptamine-induced and-amplified human platelet aggregation by ketanserin (R 41 468), a selective 5-HT2-receptor antagonist

1982 • 165 citations

Release of intracellular membrane-bound calcium precedes the onset of stimulus-induced exocytosis in platelets

1980 • 109 citations

Correlations between different measures of antiserotonin activity of drugs

1982 • 100 citations

Direct evidence for a role for Ca2+ in amine storage granule secretion by human platelets

1980 • 99 citations

Serotonin-sensitive adenylate cyclase and [3]serotonin binding sites in the CNS of the rat—I

1980 • 98 citations

The Gating Behavior of a Channel for Ca2+-Induced Ca2+ Release in Fragmented Sarcoplasmic Reticulum1

1983 • 95 citations

A study of the release of calcium from human blood platelets and its inhibition by metabolic inhibitors, N-ethylmaleimide and aspirin

1970 • 81 citations

The localization of calcium and phosphorus in human platelets

1974 • 75 citations

Pharmacological Evaluation of a New Ca<sup>++</sup> Antagonist, 8-(N, N-Diethylamino)Octyl 3,4,5-Trimethoxybenzoate Hydrochloride (TMB-8): Studies in Skeletal Muscles

1974 • 69 citations

5-hydroxytryptamine and vascular disease.

1983 • 56 citations

Membrane biochemistry. A laboratory manual on transport and bioenergetics

1980 • 51 citations

SHAPE CHANGE OF BLOOD PLATELETS—A MODEL FOR CEREBRAL 5‐HYDROXYTRYPTAMINE RECEPTORS?

1979 • 45 citations

Excitatory and inhibitory modulation of intracellular free calcium in human platelets by hormones and drugs

1983 • 40 citations

The effect of D2O and chlortetracycline on ADP-induced platelet shape change and aggregation

1976 • 32 citations

Desensitisation in Human and Rabbit Blood Platelets

1982 • 27 citations

Blood platelets isolated by polysaccharide gradients: reaction to 5-hydroxytryptamine.

1979 • 23 citations

Effect of three calcium antagonists on platelet secretion and metabolism

1981 • 23 citations

Transmitter-induced calcium current.

1981 • 14 citations

Rheo-Optical Shape Analysis of Human Blood Platelets

1982 • 10 citations

Increase of cyclic GMP in blood platelets by biogenic amines - a receptor-mediated effect?

1980 • 6 citations

Determination of the Membrane Potential and pH Difference Across the Inner Mitochondrial Membrane

1979 • 2 citations