Point mutations are associated with a gene duplication leading to the bloodstream reexpression of a trypanosome metacyclic VSG

Dideoxy sequencing method using denatured plasmid templates

1986 • 1,537 citations

DISCONTINUOUS TRANSCRIPTION AND ANTIGENIC VARIATION IN TRYPANOSOMES

1986 • 418 citations

Misalignment-mediated DNA synthesis errors

1990 • 306 citations

An analysis of cosmid clones of nuclear DNA fromTrypanosoma bruceishows that the genes for variant surface glycoproteins are clustered in the genome

1982 • 246 citations

Avian B-Cell Development: Generation of an Immunoglobulin Repertoire by Gene Conversion

1991 • 236 citations

Structure of the growing telomeres of trypanosomes

1984 • 227 citations

Identification of a telomeric DNA sequence in Trypanosoma brucei

1984 • 190 citations

On the DNA content and ploidy of trypanosomes

1982 • 169 citations

Gene conversion as a mechanism for antigenic variation in Trypanosomes

1983 • 167 citations

High frequency of antigenic variation inTrypanosoma brucei rhodesienseinfections

1989 • 136 citations

Exonucleolytic proofreading

1988 • 133 citations

Molecular biology of trypanosome antigenic variation

1985 • 114 citations

Might gene conversion be the mechanism of somatic hypermutation of mammalian immunoglobulin genes?

1989 • 94 citations

All metacyclic variable antigen types of Trypanosoma congolense identified using monoclonal antibodies

1983 • 91 citations

Active late-appearing variable surface antigen genes in Trypanosoma equiperdum are constructed entirely from pseudogenes.

1989 • 82 citations

Surface epitope variation via mosaic gene formation is potential key to long-term survival of Trypanosoma brucei

1992 • 75 citations

Antigenic diversity by the recombination of pseudogenes.

1989 • 66 citations

Molecular biology of trypanosome antigenic variation.

1985 • 65 citations

The feeding behaviour of larvae, nymphs and adults of Rhipicephalus appendiculatus

1976 • 64 citations

Characterization of the genes specifying two metacyclic variable antigen types in Trypanosoma brucei rhodesiense.

1984 • 62 citations

Trypanosoma rhodesiense blood forms express all antigen specificities relevant to protection against metacyclic (insect form) challenge.

1982 • 50 citations

Point mutations during generation of expression-linked extra copy of trypanosome surface glycoprotein gene

1982 • 46 citations

The 5′ flanking sequence of a Trypanosoma brucei variable surface glycoprotein gene

1987 • 45 citations

Metacyclic Variant Surface Glycoprotein Genes of Trypanosoma brucei Subsp. rhodesiense Are Activated In Situ, and Their Expression Is Transcriptionally Regulated

1986 • 43 citations

Mutation in a reporter gene depends on proximity to and transcription of immunoglobulin variable transgenes.

1991 • 39 citations

Genetic Rearrangement

1984 • 36 citations

Isolation and Characterization of a new Serodeme of Trypanosoma Rhodesiense *

1979 • 33 citations

Duplicative activation mechanisms of two trypanosome telomeric VSG genes with structurally simple 5′ flanks

1990 • 33 citations

Exposed epitopes on a Trypanosoma equiperdum variant surface glycoprotein altered by point mutations.

1991 • 32 citations

Control of antigenic variation in African trypanosomes.

1991 • 30 citations

Independent expression of the metacyclic and bloodstream variable antigen repertoires ofTrypanosoma brucei rhodesiense

1986 • 30 citations

Metacyclic variant surface glycoprotein genes of Trypanosoma brucei subsp. rhodesiense are activated in situ, and their expression is transcriptionally regulated.

1986 • 29 citations

Characterization of genes coding for two major metacyclic surface antigens in Trypanosoma brucei

1987 • 15 citations

Bloodstream and metacyclic variant surface glycoprotein gene expression sites of Trypanosoma brucei gambiense

1990 • 15 citations

A novel telomeric gene conversion in Trypanosoma brucei

1989 • 12 citations

Characterization and nomenclature of trypanosome serodemes and zymodemes: Report of a meeting held in Edinburgh, September 1978

1982 • 11 citations

Sequences of three VSG mRNAs expressed in a mixed population of Trypanosoma brucei rhodesiense

1990 • 5 citations