THERAPEUTIC APPROACH IN INSULIN RESISTANCE WITH ACANTHOSIS NIGRICANS

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

1985 • 29,733 citations

Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus. Provisional report of a WHO Consultation

1998 • 14,996 citations

Role of Insulin Resistance in Human Disease

1988 • 12,099 citations

Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study

2000 • 8,604 citations

Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)

1998 • 7,971 citations

Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus

1997 • 6,073 citations

Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: studies in subjects with various degrees of glucose tolerance and insulin sensitivity.

2000 • 2,358 citations

Pathogenesis of NIDDM: A Balanced Overview

1992 • 2,111 citations

Medical Hazards of Obesity

1993 • 1,428 citations

β-cells in type II diabetes mellitus

1991 • 582 citations

The Effects of Metformin on Body Mass Index and Glucose Tolerance in Obese Adolescents With Fasting Hyperinsulinemia and a Family History of Type 2 Diabetes

2001 • 443 citations

Manual of Pharmacologic Calculations

1981 • 359 citations

International Textbook of Diabetes Mellitus

1993 • 282 citations

Cardiovascular risk factors clustering with endogenous hyperinsulinaemia predict death from coronary heart disease in patients with Type II diabetes

2000 • 196 citations

Current views on obesity

1996 • 196 citations

Prevalence and Significance of Acanthosis Nigricans in an Adult Obese Population

1992 • 158 citations

Standardization of IVGTT to Predict IDDM

1992 • 136 citations

Predictive value of intravenous glucose tolerance test insulin secretion less than or greater than the first percentile in islet cell antibody positive relatives of Type 1 (insulin-dependent) diabetic patients

1991 • 118 citations

Pathophysiology of Type 2 Diabetes and Modes of Action of Therapeutic Interventions

1997 • 110 citations

Prognostically significant heterogeneity of cytoplasmic islet cell antibodies in relatives of patients with type I diabetes

1992 • 51 citations

Acanthosis Nigricans

1998 • 51 citations

Natural History of Impaired Glucose Tolerance: Follow‐up at Joslin Clinic

1996 • 49 citations

Acanthosis Nigricans: A Marker for Hyperinsulinemia

1995 • 32 citations

What therapy do our NIDDM patients need? Insulin releasers

1995 • 15 citations

Acanthosis nigricans, hyperinsulinaemia and risk factors for cardiovascular disease

2000 • 10 citations